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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_1005 [new locus tag: SAUSA300_RS05410 ]
  • pan locus tag?: SAUPAN003331000
  • symbol: SAUSA300_1005
  • pan gene symbol?: mntH
  • synonym:
  • product: manganese transport protein MntH

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_1005 [new locus tag: SAUSA300_RS05410 ]
  • symbol: SAUSA300_1005
  • product: manganese transport protein MntH
  • replicon: chromosome
  • strand: -
  • coordinates: 1100206..1101558
  • length: 1353
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGAATAATAAACGACATTCAACAAATGAACAATTAAGTTTAGACGAAATAAACAATACA
    ATTAAATTCGATCATCGCAGTTCAAATAAACAGAAATTTTTATCATTTCTTGGACCTGGG
    TTATTAGTCGCTGTTGGTTACATGGATCCCGGAAACTGGATAACATCAATGCAAGGTGGC
    GCCCAATATGGCTATACTTTGCTATTCGTAATTCTTATTTCAAGTTTATCAGCAATGTTA
    CTTCAAAGCATGACAGTGAGATTAGGAATAGCAACAGGTATGGACTTAGCTCAAATGACA
    CGACATTATTTATCAAGACCTATTGCTATAATCTTTTGGATCATTGCAGAACTAGCAATT
    ATCGCTACAGATATTGCTGAGGTTATTGGTAGTGCTATTGCTCTTAATCTCCTATTTAAC
    ATACCTTTAATCGTCGGTGCACTAATAACTGTACTTGATGTATTTTTACTACTTTTTATA
    ATGAAATATGGTTTTAGAAAAATTGAAGCTATTGTTGGTACATTAATTTTCACAGTGTTA
    TTCATCTTTATATTTGAAGTCTATATTTCATCACCACAGTTGAATGCTGTGTTAAATGGA
    TTTATACCACATAGTGAAATCATTACAAATAACGGCATTCTCTATATTGCATTAGGTATT
    ATTGGCGCTACAATTATGCCTCATAATTTGTACTTACATTCATCAATTGTACAATCTAGA
    ACATACTCAAGACATAACAATGAAGAAAAAGCGCAAGCGATTAAATTTGCTACGATAGAT
    TCGAACATTCAGTTATCAATCGCATTTGTAGTCAATTGCTTATTATTAGTGTTAGGAGCA
    TCACTATTTTTCAACTCAAATGCTGACGATTTAGGTGGTTTCTATGATTTATATCACGCC
    TTAAAAACTGAACCTGTACTAGGTGCAACAATGGGTGCAATCATGAGTACATTATTTGCA
    GTTGCATTATTAGCGTCAGGTCAAAATTCAACGATTACTGGTACTTTAGCAGGACAAATT
    GTAATGGAAGGATTTTTAAGATTACACATACCAAATTGGTTAAGACGTTTAATTACACGT
    TCTCTTGCTGTCATTCCTGTTATCGTATGCTTAATCATTTTTAAAGGTAATGCAGCTAAA
    ATTGAGCAACTACTTGTATTCTCTCAAGTATTTTTAAGTATTGCTCTGCCATTCTGTTTA
    ATACCATTACAATTGGCTACTAGTAATAAAGACTTGATGGGACCTTTCTATAATAAAACA
    TGGGTTAATATCATTTCATGGACACTTATTATTATTCTAAGTATTTTAAATGTCTATTTA
    ATCGTTCAAACATTCCAAGAACTACAAAGTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1353

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_1005 [new locus tag: SAUSA300_RS05410 ]
  • symbol: SAUSA300_1005
  • description: manganese transport protein MntH
  • length: 450
  • theoretical pI: 8.08989
  • theoretical MW: 49723.5
  • GRAVY: 0.717778

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family (TIGR01197; HMM-score: 388.6)
  • TheSEED  :
    • Manganese transport protein MntH
  • PFAM:
    APC (CL0062) Nramp; Natural resistance-associated macrophage protein (PF01566; HMM-score: 404.4)
    and 1 more
    UcrQ-like (CL0429) UcrQ; UcrQ family (PF02939; HMM-score: 11.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 11
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.025097
    • TAT(Tat/SPI): 0.046205
    • LIPO(Sec/SPII): 0.002754
  • predicted transmembrane helices (TMHMM): 10

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAMLLQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFIMKYGFRKIEAIVGTLIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSRTYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFAVALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCLIPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: MntR* (repression) regulon
    MntR*(TF)important in Manganese homeostasis; RegPrecise 

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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