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NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus USA300_FPR3757
- locus tag: SAUSA300_1256 [new locus tag: SAUSA300_RS06825 ]
- pan locus tag?: SAUPAN003750000
- symbol: msrA
- pan gene symbol?: msrA2
- synonym:
- product: methionine sulfoxide reductase A
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SAUSA300_1256 [new locus tag: SAUSA300_RS06825 ]
- symbol: msrA
- product: methionine sulfoxide reductase A
- replicon: chromosome
- strand: -
- coordinates: 1384179..1384688
- length: 510
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3913501 NCBI
- RefSeq: YP_493953 NCBI
- BioCyc: see SAUSA300_RS06825
- MicrobesOnline: 1292771 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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481ATGAATATTAATACAGCTTATTTTGCCGGAGGTTGCTTTTGGTGTATGACGAAACCATTT
GACACCTTTGACGGCATAGAAAAAGTAACTTCTGGATATATGGGCGGACATATTGAAAAT
CCTACTTACGAACAAGTAAAATCAGGTACGAGTGGTCATTTAGAAACTGTTGAAATTCAA
TATGATGTTGCATTATTCTCATACAATAAGTTATTAGAAATATTTTTCTCAGTCATTGAC
CCATTAGATACAGGTGGTCAATATCAAGACCGTGGTCCTCAATATCAAACAGCTATTTTC
TACACTAATGATCATCAAAAAGAACTCGCTGAGACTTATATCGAGCAGCTTAAAAATACG
ATTAATGCTGATAAGGCAATTGCAACAAAAATATTACCAGCGTCACAATTTTACAAAGCC
GAAGACTATCACCAAGATTTTTATAAGAAAAATCCAGAGCGCTATGCAGAAGAACAAAAA
ATACGCCAAGAATACAAAAATAAGCAATAA60
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510
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SAUSA300_1256 [new locus tag: SAUSA300_RS06825 ]
- symbol: MsrA
- description: methionine sulfoxide reductase A
- length: 169
- theoretical pI: 4.86349
- theoretical MW: 19610.7
- GRAVY: -0.739645
⊟Function[edit | edit source]
- reaction: EC 1.8.4.11? ExPASyPeptide-methionine (S)-S-oxide reductase Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin
- TIGRFAM: Cellular processes Adaptations to atypical conditions peptide-methionine (S)-S-oxide reductase (TIGR00401; EC 1.8.4.11; HMM-score: 188.7)Protein fate Protein modification and repair peptide-methionine (S)-S-oxide reductase (TIGR00401; EC 1.8.4.11; HMM-score: 188.7)
- TheSEED :
- Peptide-methionine (S)-S-oxide reductase MsrA (EC 1.8.4.11)
- PFAM: no clan defined PMSR; Peptide methionine sulfoxide reductase (PF01625; HMM-score: 198.7)and 2 moreRCDG1; Renal cancer differentiation gene 1 protein (PF15725; HMM-score: 14.4)DUF4298; Domain of unknown function (DUF4298) (PF14131; HMM-score: 13)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.047787
- TAT(Tat/SPI): 0.000356
- LIPO(Sec/SPII): 0.012765
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MNINTAYFAGGCFWCMTKPFDTFDGIEKVTSGYMGGHIENPTYEQVKSGTSGHLETVEIQYDVALFSYNKLLEIFFSVIDPLDTGGQYQDRGPQYQTAIFYTNDHQKELAETYIEQLKNTINADKAIATKILPASQFYKAEDYHQDFYKKNPERYAEEQKIRQEYKNKQ
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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