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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_2323 [new locus tag: SAUSA300_RS12840 ]
  • pan locus tag?: SAUPAN005896000
  • symbol: cobI
  • pan gene symbol?: corA2
  • synonym:
  • product: CorA family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_2323 [new locus tag: SAUSA300_RS12840 ]
  • symbol: cobI
  • product: CorA family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2496801..2497745
  • length: 945
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGATTACTTCATTCAGACATTCTGAAGATATAGATAAACATATTATAAAAACACCATTA
    GATCATACAGCGTCATGGATTAATGTAGTAGAACCAGACCGAGAAGAAATTGAAAATCTT
    ATGGAACAATATAATATACCTGAAGACTTTATACGTGACCCTTTGGACTCAGAAGAAAGT
    TCCCGTATTGAATATGACGAAGATACTGGTTACTCATTAATCATTATTGATTTACCTATC
    GTCAATTCAACTAATCGTAGCGTTCTATCTTTTGTAACGATTCCATTAGGCATTATTATT
    GGCAACGGTATTATCGTAACAGTTTGTGACGCTGAAAATGAATTTTTAGAAAATTTACCT
    AAGCGTGATATTAATTTAAAATTTCACAGCAGATTTGCATTAGAAATTTTAACTACTATT
    GCCGACCATTATAATCGTAACTTACGATTACTTAATAAAAGTAGAATTCGTATTGAGAAA
    GAACTAAAAAATAACATTACTAACAAACAACTTTTCAAATTAATGGAAGTTGAAAAAAGT
    TTAGTATACTTTTTAGCTGCCTTAAAAGGTAACGATACAATTATTAAAAAGTTATTCCGT
    TTACCTGCAATTAAACGTTTTGAAGAAGATGAAGAATTACTAGAAGATTTAATCATTGAA
    AATAACCAAGCCATCGAAACAACAGAATTACATCAACGTATCTTAGAAAGTATCACAACA
    TCATACGCTTCCTTATTATCTAATGATATGAATACGATTATGAAGACATTAACACTTTTC
    ACGGTACTATTAACGTTACCAACACTCGTATTTAGTTTCTTCGGTATGAATGTGCCGTTG
    CCAATTGATGACCATAGTTATATATCTTGGATTATTGTGGTAGGTATTTCATTAATTCTT
    GTCGTAATTGTTAGTATTTTCTTATGGCGTAAACAGAAATTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    945

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_2323 [new locus tag: SAUSA300_RS12840 ]
  • symbol: CobI
  • description: CorA family protein
  • length: 314
  • theoretical pI: 4.71169
  • theoretical MW: 36360.8
  • GRAVY: 0.038535

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds magnesium and cobalt transport protein CorA (TIGR00383; HMM-score: 100.9)
  • TheSEED  :
    • Magnesium and cobalt transport protein CorA
  • PFAM:
    no clan defined CorA; CorA-like Mg2+ transporter protein (PF01544; HMM-score: 198)
    and 4 more
    DUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 20.2)
    SIT; SHP2-interacting transmembrane adaptor protein, SIT (PF15330; HMM-score: 10.5)
    CPA_AT (CL0064) Mem_trans; Membrane transport protein (PF03547; HMM-score: 10.3)
    Tetraspannin (CL0347) CD20; CD20-like family (PF04103; HMM-score: 9.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 2
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002237
    • TAT(Tat/SPI): 0.000297
    • LIPO(Sec/SPII): 0.000766
  • predicted transmembrane helices (TMHMM): 2

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MITSFRHSEDIDKHIIKTPLDHTASWINVVEPDREEIENLMEQYNIPEDFIRDPLDSEESSRIEYDEDTGYSLIIIDLPIVNSTNRSVLSFVTIPLGIIIGNGIIVTVCDAENEFLENLPKRDINLKFHSRFALEILTTIADHYNRNLRLLNKSRIRIEKELKNNITNKQLFKLMEVEKSLVYFLAALKGNDTIIKKLFRLPAIKRFEEDEELLEDLIIENNQAIETTELHQRILESITTSYASLLSNDMNTIMKTLTLFTVLLTLPTLVFSFFGMNVPLPIDDHSYISWIIVVGISLILVVIVSIFLWRKQKL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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