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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS07135 [old locus tag: SAUSA300_1310 ]
  • pan locus tag?: SAUPAN003842000
  • symbol: SAUSA300_RS07135
  • pan gene symbol?: pgpB
  • synonym:
  • product: phosphatase PAP2 family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_RS07135 [old locus tag: SAUSA300_1310 ]
  • symbol: SAUSA300_RS07135
  • product: phosphatase PAP2 family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1443799..1444413
  • length: 615
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGAGTCAATGGAAACGTATCTCTTTGCTCATCGTTTTTACATTGGTTTTTGGAATTATC
    GCGTTTTTCCACGAATCAAGACTTGGGAAATGGATTGATAATGAAGTTTATGAGTTTGTA
    TATTCATCAGAGAGCTTTATTACGACATCTATCATGCTTGGGGCTACTAAAGTAGGTGAA
    GTCTGGGCAATGTTATGTATTTCATTACTTCTTGTGGCATATCTCATGTTAAAGCGCCAC
    AAAATTGAAGCATTATTTTTTGCATTAACAATGGCATTATCTGGAATTTTGAATCCAGCA
    TTAAAAAATATATTCGATAGAGAAAGACCTACATTGCTGCGTTTAATTGATATAACAGGA
    TTTAGTTTTCCTAGCGGTCATGCTATGGGATCAACTGCATATTTTGGAAGTGGTATCTAT
    CTATTAAATCGATTAAATCAAGGTAATTCAAAAGGTATTCTTATAGGGTTATGTGCAGCT
    ATGATTTTATTGATTTCCATATCACGTGTATATCTAGGTGTACATTATCCAACAGATATT
    ATTGCCGGCATTATTGGTGGATTATTTTGCATTATTTTATCAACGTTATTACTTAGAAAT
    AAATTAATAAATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    615

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_RS07135 [old locus tag: SAUSA300_1310 ]
  • symbol: SAUSA300_RS07135
  • description: phosphatase PAP2 family protein
  • length: 204
  • theoretical pI: 9.63103
  • theoretical MW: 22715.1
  • GRAVY: 0.770588

⊟Function[edit | edit source]

  • reaction:
    EC 3.1.3.27?  ExPASy
    Phosphatidylglycerophosphatase Phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate
  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking signal peptidase II (TIGR00077; EC 3.4.23.36; HMM-score: 14.8)
    and 1 more
    Cell structure Cell envelope Other TIGR01666 family membrane protein (TIGR01666; HMM-score: 9.2)
  • TheSEED: see SAUSA300_1310
  • PFAM:
    pap2 (CL0525) PAP2; PAP2 superfamily (PF01569; HMM-score: 76.3)
    and 4 more
    PAP2_3; PAP2 superfamily (PF14378; HMM-score: 34.9)
    PAP2_C; PAP2 superfamily C-terminal (PF14360; HMM-score: 8.1)
    no clan defined Tmemb_170; Putative transmembrane protein 170 (PF10190; HMM-score: 7.7)
    Peptidase_A8; Signal peptidase (SPase) II (PF01252; HMM-score: 6.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.077608
    • TAT(Tat/SPI): 0.000521
    • LIPO(Sec/SPII): 0.01373
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSQWKRISLLIVFTLVFGIIAFFHESRLGKWIDNEVYEFVYSSESFITTSIMLGATKVGEVWAMLCISLLLVAYLMLKRHKIEALFFALTMALSGILNPALKNIFDRERPTLLRLIDITGFSFPSGHAMGSTAYFGSGIYLLNRLNQGNSKGILIGLCAAMILLISISRVYLGVHYPTDIIAGIIGGLFCIILSTLLLRNKLIN

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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