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PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS10745 [old locus tag: SAUSA300_1959 ]
  • pan locus tag?: SAUPAN001396000
  • symbol: SAUSA300_RS10745
  • pan gene symbol?: —
  • synonym:
  • product: MBL fold metallo-hydrolase

⊟Additional information (user-provided)[edit | edit source]

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_RS10745 [old locus tag: SAUSA300_1959 ]
  • symbol: SAUSA300_RS10745
  • product: MBL fold metallo-hydrolase
  • replicon: chromosome
  • strand: -
  • coordinates: 2116032..2116649
  • length: 618
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATAAAATTTGAACGTGTTCAAAAGCATTTCAAATATAAAACAAGACATATAGCAGGGTGT
    CTTATCACACACGAACATGGTGATCATGCAAAGTATACAAAGCAGTTTGTCGACAATGGT
    GTAATCAGCTATATGACTGCTGGAACACAACAAGCTATGAATTTTGAAAGTCATCGCTTA
    TGCACGATTAAGGCAAAGCAAGAGCTGCGAATAGGTACATGGTCAATTCTACCGTTTGAC
    ATCGAACATGATGCTAACGAGCCTGTGGCTTTCTTATTACAAAGCACACTAGGTTATAAG
    GTTCTGTATGTTACTGATACAAAGTATTTGAAATACAAATTTAATGGCATTACGCACATG
    ATGCTAGAAGTTAATTATATCTATGAACAAATGCAAGAAAACATAAAAAACGGCAGTGTG
    CACAGCACATTAGCAAACAGAATTATGGAGTCTCATTTTAGCTTAGAACATGCTATCGGA
    ATGTTAAAAGCAAATGATTTAACTAGACTCGAAGAAATACATTTAATTCATTTAAGTAGT
    CAAAATTCAAATGCAAAATACATTAAAAGTGAAATACAAAAAGTGACGGGCGCGCCCGTT
    TATTTTGGAGGTTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    618


⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_RS10745 [old locus tag: SAUSA300_1959 ]
  • symbol: SAUSA300_RS10745
  • description: MBL fold metallo-hydrolase
  • length: 205
  • theoretical pI: 8.92554
  • theoretical MW: 23641
  • GRAVY: -0.357073

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Detoxification hydroxyacylglutathione hydrolase (TIGR03413; EC 3.1.2.6; HMM-score: 18.6)
    and 1 more
    Genetic information processing Transcription RNA processing ribonuclease Z (TIGR02651; EC 3.1.26.11; HMM-score: 11)
  • TheSEED: see SAUSA300_1959
  • PFAM:
    Metallo-HOrase (CL0381) Lactamase_B_2; Beta-lactamase superfamily domain (PF12706; HMM-score: 34.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9328
    • Cytoplasmic Membrane Score: 0.0328
    • Cell wall & surface Score: 0.0004
    • Extracellular Score: 0.034
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.013026
    • TAT(Tat/SPI): 0.000949
    • LIPO(Sec/SPII): 0.002487
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKFERVQKHFKYKTRHIAGCLITHEHGDHAKYTKQFVDNGVISYMTAGTQQAMNFESHRLCTIKAKQELRIGTWSILPFDIEHDANEPVAFLLQSTLGYKVLYVTDTKYLKYKFNGITHMMLEVNYIYEQMQENIKNGSVHSTLANRIMESHFSLEHAIGMLKANDLTRLEEIHLIHLSSQNSNAKYIKSEIQKVTGAPVYFGGL

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Additional information (user-provided)[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Other information (user-provided)[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]


⊟Relevant publications[edit | edit source]