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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

organism: Staphylococcus aureus USA300_FPR3757
locus tag: SAUSA300_RS13705 [old locus tag: SAUSA300_2470 ]
pan locus tag^?: SAUPAN006184000
symbol: SAUSA300_RS13705
pan gene symbol^?: sdaAB
synonym:
product: L-serine dehydratase, iron-sulfur-dependent subunit beta

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

type: CDS
locus tag: SAUSA300_RS13705 [old locus tag: SAUSA300_2470 ]
symbol: SAUSA300_RS13705
product: L-serine dehydratase, iron-sulfur-dependent subunit beta
replicon: chromosome
strand: -
coordinates: 2666319..2666999
length: 681
essential: unknown other strains

⊟Accession numbers[edit | edit source]

Location: NC_007793 (2666319..2666999) NCBI
BioCyc: SAUSA300_RS13705 BioCyc
MicrobesOnline: see SAUSA300_2470

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

1
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541
601
661
ATGGCAAAGAGCTATGATTATCAAAGTGCTTTCGATATTATCGGACCAGTTATGATGGGC
CCTTCAAGTTCTCATACGGCTGGTGCAGTAAAGATTGGGAATTCAGCACGCGCAATATTG
GGAGATATTCCTAAAAATATTGAAATACATTATTATGAATCATTTGCTCAAACACACCAA
GGACATGGTACAGATGTCGCTATTGTGGGTGGAGCAATGGGATATTCAACATTTGATAAC
CGAATTAAATCTTCATTAGAAATTGCAGCTGATGATGGTATTAAAATAGATATCATCGAA
GAAGAAGGCGATAGTATTGGTCAACATCCAAACTGTGCTTATATCAAATCATCTCGTAAT
GATGGTCGCTACATTGAAATTATCGGTATTTCAATCGGTGGTGGTACAATTAAAATTAAA
GGTATTCATATAAATGGACTAGAAGTAGATTTAAATCATGGATTACCAATTTTAGTTGTT
GACGGAAATATGACTAAAGCACAAGTAAATCATTTCATCAATGATATCAACGATATGAAA
TTAGACTGTAAAGATGAATTTATTAAGATAGATGAAGATAAATGCTTGGTTGTAATACCA
TTAAATAAAGCAATCTCAGAATCAACATTAAATACAATTAAAGAGAAATACAGTGACGTA
AACGTTTCCTATATAAATTAG
60
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681

⊟Protein[edit | edit source]

⊟General[edit | edit source]

locus tag: SAUSA300_RS13705 [old locus tag: SAUSA300_2470 ]
symbol: SAUSA300_RS13705
description: L-serine dehydratase, iron-sulfur-dependent subunit beta
length: 226
theoretical pI: 4.93024
theoretical MW: 24557.6
GRAVY: -0.15531

⊟Function[edit | edit source]

reaction:
EC 4.3.1.17? ExPASy
L-serine ammonia-lyase L-serine = pyruvate + NH₃
TIGRFAM:
Metabolism Energy metabolism Amino acids and amines L-serine dehydratase, iron-sulfur-dependent, beta subunit (TIGR00719; EC 4.3.1.17; HMM-score: 170.8)
Metabolism Energy metabolism Glycolysis/gluconeogenesis L-serine dehydratase, iron-sulfur-dependent, beta subunit (TIGR00719; EC 4.3.1.17; HMM-score: 170.8)
and 2 more
Metabolism Energy metabolism Amino acids and amines L-serine ammonia-lyase (TIGR00720; EC 4.3.1.17; HMM-score: 32.4)
Metabolism Energy metabolism Glycolysis/gluconeogenesis L-serine ammonia-lyase (TIGR00720; EC 4.3.1.17; HMM-score: 32.4)
TheSEED: see SAUSA300_2470
PFAM:
no clan defined SDH_beta; Serine dehydratase beta chain (PF03315; HMM-score: 46.2)
and 1 more
Ribokinase (CL0118) ADP_PFK_GK; ADP-specific Phosphofructokinase/Glucokinase conserved region (PF04587; HMM-score: 11.6)

⊟Structure, modifications & cofactors[edit | edit source]

domains:
modifications:
cofactors:
effectors:

⊟Localization[edit | edit source]

PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
LocateP:
SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.075135
- TAT(Tat/SPI): 0.026519
- LIPO(Sec/SPII): 0.003757
predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

GI: 447062978 NCBI
RefSeq: WP_001140234 NCBI
UniProt: see SAUSA300_2470

⊟Protein sequence[edit | edit source]

MAKSYDYQSAFDIIGPVMMGPSSSHTAGAVKIGNSARAILGDIPKNIEIHYYESFAQTHQGHGTDVAIVGGAMGYSTFDNRIKSSLEIAADDGIKIDIIEEEGDSIGQHPNCAYIKSSRNDGRYIEIIGISIGGGTIKIKGIHINGLEVDLNHGLPILVVDGNMTKAQVNHFINDINDMKLDCKDEFIKIDEDKCLVVIPLNKAISESTLNTIKEKYSDVNVSYIN

⊟Experimental data[edit | edit source]

experimentally validated: data available for NCTC8325
protein localization:
quantitative data / protein copy number per cell:
interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

regulator: CcpA see SAUSA300_2470

⊟Transcription pattern[edit | edit source]

S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

Aureolib: no data available

⊟Protein stability[edit | edit source]

half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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