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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS14395 [old locus tag: SAUSA300_2589 ]
  • pan locus tag?: SAUPAN006390000
  • symbol: SAUSA300_RS14395
  • pan gene symbol?: sasA
  • synonym:
  • product: serine-rich repeat glycoprotein adhesin SasA

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_RS14395 [old locus tag: SAUSA300_2589 ]
  • symbol: SAUSA300_RS14395
  • product: serine-rich repeat glycoprotein adhesin SasA
  • replicon: chromosome
  • strand: -
  • coordinates: 2811367..2818182
  • length: 6816
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    5701
    5761
    5821
    5881
    5941
    6001
    6061
    6121
    6181
    6241
    6301
    6361
    6421
    6481
    6541
    6601
    6661
    6721
    6781
    ATGAGTAAAAGACAGAAAGCATTTCATGACAGCTTAGCAAACGAAAAAACAAGAGTAAGA
    CTTTATAAATCTGGAAAAAATTGGGTAAAATCCGGAATTAAAGAAATAGAAATGTTCAAA
    ATTATGGGGCTACCATTTATTAGTCATAGTTTAGTGAGTCAAGATAATCAAAGCATTAGT
    AAAAAAATGACGGGATACGGACTGAAAACTACGGCGGTTATTGGTGGTGCATTCACGGTA
    AATATGTTGCATGACCAGCAAGCTTTTGCGGCTTCTGATGCACCATTAACTTCTGAATTA
    AACACACAAAGTGAAACAGTAGGTAATCAAAACTCAACGACAATCGAAGCATCAACATCA
    ACAGCCGATTCCACAAGTGTAACGAAAAATAGTAGTTCGGTACAAACATCAAATAGTGAC
    ACAGTCTCAAGTGAAAAGTCTGAAAAGGTCACTTCGACAACTAATAGTACAAGCAATCAA
    CAAGAGAAATTGACATCTACATCAGAATCAACATCCTCAAAGAATACTACATCAAGTTCT
    GATACTAAATCTGTAGCTTCAACTTCAAGTACAGAACAACCAATTAATACATCAACAAAT
    CAAAGTACTGCATCAAATAACACTTCACAAAGCACAACGCCATCTTCGGTCAACTTAAAC
    AAAACTAGCACAACGTCAACTAGCACCGCACCAGTAAAACTTCGAACTTTCAGTCGCTTA
    GCTATGTCAACATTTGCGTCAGCAGCGACGACAACCGCAGTAACTGCTAATACAATTACA
    GTTAATAAAGATAACTTAAAACAATATATGACAACGTCAGGTAATGCTACCTATGATCAA
    AGTACCGGTATTGTGACGTTAACACAGGATGCATACAGCCAAAAAGGTGCTATTACATTA
    GGAACACGTATTGACTCTAATAAGAGTTTTCATTTTTCTGGAAAAGTAAATTTAGGTAAC
    AAATATGAAGGGCATGGAAATGGTGGAGATGGTATCGGTTTTGCCTTTTCACCAGGTGTA
    TTAGGTGAAACAGGGTTAAACGGTGCCGCAGTAGGTATTGGTGGCTTAAGTAACGCATTT
    GGCTTCAAATTGGATACGTATCACAATACATCTAAACCAAATTCAGCTGCAAAGGCGAAT
    GCTGACCCATCTAATGTAGCTGGTGGAGGTGCGTTTGGTGCATTTGTAACAACAGATAGT
    TATGGTGTTGCGACAACGTATACATCAAGTTCAACAGCTGATAATGCTGCGAAGTTAAAT
    GTTCAACCTACAAATAACACGTTCCAAGATTTTGATATTAACTATAATGGTGATACAAAG
    GTTATGACTGTCAAATATGCAGGTCAAACATGGACACGTAATATTTCAGATTGGATTGCG
    AAAAGTGGTACGACCAACTTTTCATTATCAATGACAGCCTCAACAGGTGGCGCGACAAAT
    TTACAACAAGTACAATTTGGAACATTCGAATATACAGAGTCTGCTGTTACACAAGTGAGA
    TACGTTGATGTAACAACAGGTAAAGATATTATTCCACCAAAAACATATTCAGGAAATGTT
    GATCAAGTCGTGACAATCGATAATCAGCAATCTGCATTGACTGCTAAAGGATATAACTAC
    ACGTCCGTCGATAGTTCATATGCGTCAACTTATAATGATACAAATAAAACTGTAAAAATG
    ACGAATGCTGGACAATCAGTGACATATTATTTTACTGATGTAAAAGCACCAACTGTAACT
    GTAGGCAATCAAACCATAGAAGTGGGTAAAACAATGAATCCTATTGTATTGACTACAACG
    GATAATGGTACTGGGACTGTGACAAATACAGTTACAGGATTACCAAGCGGATTAAGTTAC
    GATAGTGCAACGAATTCAATCATTGGGACACCAACAAAAATTGGTCAATCAACAGTGACA
    GTTGTGTCTACTGACCAAGCAAATAACAAATCGACGACAACTTTTACAATAAATGTTGTG
    GATACGACAGCACCAACAGTGACACCAATAGGAGATCAATCATCAGAAGTGTATTCACCA
    ATATCCCCGATTAAAATTGCTACGCAAGATAACAGTGGAAATGCGGTGACGAATACAGTG
    ACTGGATTGCCATCCGGACTAACATTTGATAGTACAAATAATACTATTAGTGGTACACCA
    ACAAACATTGGTACAAGTACTATATCAATCGTTTCTACAGATGCGAGCGGTAACAAAACG
    ACGACAACTTTTAAATATGAAGTAACAAGAAATAGCATGAGTGATTCCGTATCAACATCA
    GGAAGTACACAACAATCTCAAAGTGTGTCAACAAGTAAAGCTGACTCACAAAGTGCATCA
    ACGAGTACATCAGGATCGATTGTGGTATCTACATCAGCTAGTACCTCGAAATCGACAAGT
    GTAAGCCTATCTGATTCTGTGAGTGCATCTAAGTCATTAAGCACATCTGAAAGTAATAGT
    GTATCAAGCTCAACAAGCACAAGTTTAGTGAATTCACAAAGTGTATCATCAAGCATGTCG
    GATTCAGCTAGTAAATCAACATCATTAAGCGATTCTATTTCAAACTCTAGCAGTACTGAA
    AAATCCGAAAGTCTATCAACAAGTACATCTGATTCATTGCGTACATCAACATCACTCAGT
    GACTCATTAAGTATGAGTACATCAGGAAGCTTGTCTAAGTCACAAAGCTTATCAACGAGT
    ATATCAGGGTCGTCTAGTACATCAGCATCATTAAGTGACAGTACATCGAATGCAATTAGT
    ACATCAACATCATTGAGCGAGTCAGCTAGCACCTCGGACTCTATCAGTATTTCAAATAGC
    ATAGCCAACTCTCAAAGTGCGTCAACAAGCAAATCAGATTCACAAAGTACATCAATATCA
    TTAAGTACAAGTGATTCAAAATCGATGAGTACATCAGAATCATTGAGCGATTCGACGAGC
    ACAAGTGGTTCTGTTTCTGGATCACTAAGCATAGCAGCATCACAAAGTGTCTCAACAAGT
    ACATCAGACTCGATGAGTACTTCAGAGATAGTAAGTGACTCTATCAGTACAAGTGGGTCA
    TTATCTGCATCAGACAGTAAATCAATGTCCGTAAGTAGTTCAATGAGCACGTCTCAGTCA
    GGTAGTACATCAGAATCATTAAGTGATTCACAAAGTACATCTGATTCTGATAGTAAGTCA
    TTATCACAAAGTACTAGTCAATCAGGTTCAACAAGTACATCAACGTCGACAAGTGCTTCA
    GTACGTACTTCGGAATCACAAAGTACGTCTGGTTCAATGAGTGCAAGTCAATCCGATTCA
    ATGAGCATATCAACGTCGTTTAGTGATTCAACGAGTGATAGCAAATCAGCATCAACTGCA
    TCAAGTGAATCAATATCACAAAGTGCTTTTACGAGCACATCTGGTTCGGTAAGTACTTCG
    ACATCGTTAAGTACAAGTAATTCAGAACGTACATCAACATCTATGAGTGATTCCACAAGC
    TTAAGTACATCAGAGTCTGATTCAATAAGTGAATCAACGTCAACGAGCGACTCTATAAGT
    GAAGCAATATCTGCTTCAGAGAGCACGTTTATATCATTAAGTGAATCAAATAGTACTAGC
    GATTCAGAATCACAAAGTGCATCTGCCTTTTTAAGTGAATCATTAAGTGAAAGTACGTCT
    GAATCAACATCAGAGTCAGTGAGTAGTTCGACAAGTGAGAGTACGTCATTATCAGACAGT
    ACATCAGAATCTGGTAGCACATCAACATCATTAAGTAATTCAACAAGTGGTAGTACGTCC
    ATTTCAACATCGACAAGTATCAGTGAATCAACGTCAACGTTTAAGAGCGAGAGTGTTTCA
    ACATCACTGAGTATGTCAACGAGTACAAGTTTGTCTGACTCTACAAGTTTGTCAACATCA
    TTAAGTGATTCCACAAGTGATAGTAAGTCTGATTCATTAAGTACATCAATGTCGACAAGT
    GATTCAATCAGTACAAGTAAATCTGATTCCATTAGTACATCCACATCATTAAGTGGTTCT
    ACAAGTGAAAGTGAATCCGACTCAACATCATCAAGTGAAAGTAAATCCGATTCAACATCA
    ATGAGCATAAGTATGTCTCAATCAACATCAGGAAGTACAAGTACGTCAACGAGTACAAGT
    TTGTCTGACTCAACGAGTACATCATTGTCACTAAGTGCCTCAATGAATCAAAGCGGAGTA
    GACTCAAACTCAGCAAGCCAAAGTGCCTCAAACTCAACAAGTACAAGCACGAGCGAATCC
    GATTCACAAAGCACATCATCATATACAAGTCAGTCAACAAGCCAAAGTGAATCCACATCG
    ACATCAACGTCACTAAGCGATTCAACAAGTATATCTAAAAGTACGAGTCAATCAGGTTCG
    GTAAGCACATCAGCGTCATTAAGTGGTTCAGAGAGTGAATCTGATTCACAAAGTATCTCA
    ACAAGTGCAAGTGAGTCAACATCAGAAAGTGCGTCAACATCACTCAGTGACTCAACAAGT
    ACAAGTAACTCAGGATCAGCAAGTACGTCAACATCGCTCAGTAACTCAGCAAGCGCAAGT
    GAATCCGATTTGTCGTCAACATCTTTAAGTGATTCAACATCTGCGTCAATGCAAAGCAGT
    GAATCCGATTCACAAAGCACATCAGCATCATTAAGTGATTCGCTAAGTACATCAACTTCA
    AACCGCATGTCGACCATTGCAAGTTTATCTACATCGGTAAGTACATCAGAGTCTGGCTCA
    ACATCAGAAAGTACAAGTGAATCCGATTCAACATCAACATCATTAAGCGATTCACAAAGC
    ACATCAAGAAGTACAAGTGCATCAGGATCAGCAAGTACATCAACATCAACAAGTGACTCT
    CGTAGTACATCAGCTTCAACTAGTACTTCGATGCGTACAAGTACTAGTGATTCACAAAGT
    ATGTCGCTTTCGACAAGTACATCAACAAGTATGAGTGATTCAACGTCATTATCTGATAGT
    GTTAGTGATTCAACATCAGACTCAACAAGTGCGAGTACATCTGGTTCGATGAGTGTGTCT
    ATATCGTTAAGTGATTCGACAAGTACATCAACATCGGCTAGTGAAGTAATGAGCGCAAGC
    ATATCTGATTCACAAAGTATGTCAGAATCTGTAAATGATTCAGAAAGTGTAAGTGAATCT
    AATTCTGAAAGTGACTCTAAATCGATGAGTGGCTCAACAAGTGTCAGTGATTCTGGCTCA
    TTGAGCGTCTCAACGTCATTAAGAAAATCAGAAAGTGTAAGCGAGTCAAGTTCATTGAGT
    TGCTCACAATCGATGAGCGATTCAGTAAGCACAAGCGATTCGTCATCATTAAGTGTATCG
    ACGTCACTAAGAAGTTCAGAAAGCGTGAGTGAATCTGATTCATTAAGTGATTCAAAATCA
    ACAAGTGGTTCGACTTCAACAAGTACATCTGGTTCATTGAGTACCTCAACATCATTAAGT
    GGTTCAGAAAGCGTAAGCGAGTCTACCTCGCTAAGTGATTCAATATCAATGAGTGATTCT
    ACTAGTACAAGTGACTCCGACTCATTAAGTGGATCAATATCTTTAAGTGGTTCCACAAGT
    CTTAGCACTTCGGATTCATTAAGTGATTCAAAATCATTGAGTAGCTCGCAAAGTATGAGT
    GGATCAGAATCAACGTCAACAAGTGTGAGCGATTCGCAGTCAAGCTCAACAAGTAATAGT
    CAATTTGACTCTATGAGCATCAGTGCATCAGAAAGCGACTCAATGTCTACAAGTGATTCG
    TCTAGCATCAGTGGATCAAATTCAACGAGTACATCACTTTCAACATCTGACTCAATGAGC
    GGAAGCGTATCAGTTTCAACATCGACAAGTTTAAGTGACTCAATATCAGGTTCAACAAGT
    GTAAGTGACTCGAGCTCAACAAGCACATCTACATCATTAAGTGATTCAATGTCACAAAGC
    CAGTCAACAAGTACAAGTGCATCTGGTTCCTTAAGTACATCGATATCAACATCAATGTCA
    ATGAGTGCTAGTACATCGTCATCACAAAGCACATCGGTGTCGACATCATTATCAACATCA
    GACAGTATCAGTGATTCTACTTCAATAAGTATCAGTGGTTCACAAAGTACAGTAGAATCA
    GAATCTACAAGTGATTCAACTTCTATCAGTGACTCAGAATCATTGAGTACATCAGATTCA
    GACTCGACATCGACAAGTACATCGGACTCAACAAGTGGTTCAACTTCAACAAGCATATCT
    GAATCATTAAGTACGTCTGGTTCAGGTTCAACGAGCGTATCTGACTCAACATCAATGAGT
    GAATCTAATTCATCGAGTGTTTCAATGTCACAAGACAAATCCGACTCAACATCAATTAGT
    GACTCAGAATCAGTGTCAACAAGCACATCAACGTCATTGAGCACATCCGATTCGACAAGC
    ACATCCGAATCACTGAGTACATCTATGTCTGGTTCACAAAGCATTTCTGACTCAACATCA
    ACAAGTATGTCCGGCTCAACAAGTACATCCGAATCTAACTCAATGCATCCGTCAGACTCA
    ATGAGTATGCATCATACTCACAGCACGAGCACATCTCGCTTATCAAGTGAAGCAACAACG
    AGCACGAGTGAATCTCAGTCTACATTAAGTGCAACATCTGAAGTGACTAAACATAATGGC
    ACACCAGCACAAAGTGAAAAAAGATTGCCAGATACAGGTGACTCAATAAAACAAAATGGA
    TTACTAGGTGGCGTTATGACATTATTAGTTGGTTTAGGTTTAATGAAGAGAAAGAAAAAG
    AAAGATGAAAATGATCAAGATGATTCTCAAGCATAA
    60
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    6816

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAUSA300_RS14395 [old locus tag: SAUSA300_2589 ]
  • symbol: SAUSA300_RS14395
  • description: serine-rich repeat glycoprotein adhesin SasA
  • length: 2271
  • theoretical pI: 3.97105
  • theoretical MW: 228076
  • GRAVY: -0.537517

Function[edit | edit source]

  • TIGRFAM:
    KxYKxGKxW signal peptide (TIGR03715; HMM-score: 28.4)
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 24.4)
  • TheSEED: see SAUSA300_2589
  • PFAM:
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 34.2)
    and 1 more
    E-set (CL0159) HYR; HYR domain (PF02494; HMM-score: 13.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.01278
    • TAT(Tat/SPI): 0.001466
    • LIPO(Sec/SPII): 0.001104
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MSKRQKAFHDSLANEKTRVRLYKSGKNWVKSGIKEIEMFKIMGLPFISHSLVSQDNQSISKKMTGYGLKTTAVIGGAFTVNMLHDQQAFAASDAPLTSELNTQSETVGNQNSTTIEASTSTADSTSVTKNSSSVQTSNSDTVSSEKSEKVTSTTNSTSNQQEKLTSTSESTSSKNTTSSSDTKSVASTSSTEQPINTSTNQSTASNNTSQSTTPSSVNLNKTSTTSTSTAPVKLRTFSRLAMSTFASAATTTAVTANTITVNKDNLKQYMTTSGNATYDQSTGIVTLTQDAYSQKGAITLGTRIDSNKSFHFSGKVNLGNKYEGHGNGGDGIGFAFSPGVLGETGLNGAAVGIGGLSNAFGFKLDTYHNTSKPNSAAKANADPSNVAGGGAFGAFVTTDSYGVATTYTSSSTADNAAKLNVQPTNNTFQDFDINYNGDTKVMTVKYAGQTWTRNISDWIAKSGTTNFSLSMTASTGGATNLQQVQFGTFEYTESAVTQVRYVDVTTGKDIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQSVTYYFTDVKAPTVTVGNQTIEVGKTMNPIVLTTTDNGTGTVTNTVTGLPSGLSYDSATNSIIGTPTKIGQSTVTVVSTDQANNKSTTTFTINVVDTTAPTVTPIGDQSSEVYSPISPIKIATQDNSGNAVTNTVTGLPSGLTFDSTNNTISGTPTNIGTSTISIVSTDASGNKTTTTFKYEVTRNSMSDSVSTSGSTQQSQSVSTSKADSQSASTSTSGSIVVSTSASTSKSTSVSLSDSVSASKSLSTSESNSVSSSTSTSLVNSQSVSSSMSDSASKSTSLSDSISNSSSTEKSESLSTSTSDSLRTSTSLSDSLSMSTSGSLSKSQSLSTSISGSSSTSASLSDSTSNAISTSTSLSESASTSDSISISNSIANSQSASTSKSDSQSTSISLSTSDSKSMSTSESLSDSTSTSGSVSGSLSIAASQSVSTSTSDSMSTSEIVSDSISTSGSLSASDSKSMSVSSSMSTSQSGSTSESLSDSQSTSDSDSKSLSQSTSQSGSTSTSTSTSASVRTSESQSTSGSMSASQSDSMSISTSFSDSTSDSKSASTASSESISQSAFTSTSGSVSTSTSLSTSNSERTSTSMSDSTSLSTSESDSISESTSTSDSISEAISASESTFISLSESNSTSDSESQSASAFLSESLSESTSESTSESVSSSTSESTSLSDSTSESGSTSTSLSNSTSGSTSISTSTSISESTSTFKSESVSTSLSMSTSTSLSDSTSLSTSLSDSTSDSKSDSLSTSMSTSDSISTSKSDSISTSTSLSGSTSESESDSTSSSESKSDSTSMSISMSQSTSGSTSTSTSTSLSDSTSTSLSLSASMNQSGVDSNSASQSASNSTSTSTSESDSQSTSSYTSQSTSQSESTSTSTSLSDSTSISKSTSQSGSVSTSASLSGSESESDSQSISTSASESTSESASTSLSDSTSTSNSGSASTSTSLSNSASASESDLSSTSLSDSTSASMQSSESDSQSTSASLSDSLSTSTSNRMSTIASLSTSVSTSESGSTSESTSESDSTSTSLSDSQSTSRSTSASGSASTSTSTSDSRSTSASTSTSMRTSTSDSQSMSLSTSTSTSMSDSTSLSDSVSDSTSDSTSASTSGSMSVSISLSDSTSTSTSASEVMSASISDSQSMSESVNDSESVSESNSESDSKSMSGSTSVSDSGSLSVSTSLRKSESVSESSSLSCSQSMSDSVSTSDSSSLSVSTSLRSSESVSESDSLSDSKSTSGSTSTSTSGSLSTSTSLSGSESVSESTSLSDSISMSDSTSTSDSDSLSGSISLSGSTSLSTSDSLSDSKSLSSSQSMSGSESTSTSVSDSQSSSTSNSQFDSMSISASESDSMSTSDSSSISGSNSTSTSLSTSDSMSGSVSVSTSTSLSDSISGSTSVSDSSSTSTSTSLSDSMSQSQSTSTSASGSLSTSISTSMSMSASTSSSQSTSVSTSLSTSDSISDSTSISISGSQSTVESESTSDSTSISDSESLSTSDSDSTSTSTSDSTSGSTSTSISESLSTSGSGSTSVSDSTSMSESNSSSVSMSQDKSDSTSISDSESVSTSTSTSLSTSDSTSTSESLSTSMSGSQSISDSTSTSMSGSTSTSESNSMHPSDSMSMHHTHSTSTSRLSSEATTSTSESQSTLSATSEVTKHNGTPAQSEKRLPDTGDSIKQNGLLGGVMTLLVGLGLMKRKKKKDENDQDDSQA

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]