PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS00735 [old locus tag: SA0116 ]
• pan locus tag^?: SAUPAN000919000
• symbol: SA_RS00735
• pan gene symbol^?: sbnE
• synonym:
• product: IucA/IucC family siderophore biosynthesis protein

⊟Additional information (user-provided)

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS00735 [old locus tag: SA0116 ]
• symbol: SA_RS00735
• product: IucA/IucC family siderophore biosynthesis protein
• replicon: chromosome
• strand: +
• coordinates: 133773..135509
• length: 1737
• essential: no DEG other strains

⊟Accession numbers

• Location: NC_002745 (133773..135509) NCBI
• BioCyc: SA_RS00735 BioCyc
• MicrobesOnline: see SA0116

⊟Phenotype

⊟Additional information (user-provided)

⊟DNA sequence

• 1
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  1561
  1621
  1681
  
  GTGCAAAATAAAGAATTAATACAACATGCAGCGTATGCGGCTATCGAACGCATTTTAAAT
  GAATATTTTAGAGAAGAAAATTTATATCAAGTACCACCTCAAAATCATCAATGGTCTATA
  CAATTATCAGAGCTCGAAACTTTAACGGGTGAATTTCGCTATTGGTCTGCGATGGGGCAT
  CATATGTATCATCCAGAGGTATGGCTTATCGATGGAAAAAGTAAAAAAATAACAACTTAT
  AAAGAAGCAATTGCGCGTATTTTGCAACATATGGCTCAAAGTGCAGATAATCAAACGGCA
  GTGCAACAACATATGGCGCAAATTATGTCTGACATCGATAATAGCATTCATCGCACGGCG
  CGTTATTTGCAAAGTAACACAATAGACTACGTAGAGGATCGTTATATCGTTTCAGAACAA
  TCTTTATACTTAGGTCATCCATTTCATCCGACTCCTAAGAGTGCAAGTGGGTTTTCAGAA
  GCAGATTTAGAGAAATATGCACCCGAATGTCATACATCATTCCAATTGCATTATTTAGCT
  GTGCATCAAGATGTTCTGCTCACGCGCTATGTAGAAGGTAAAGAAGATCAGGTTGAGAAA
  GTGTTGTATCAATTAGCAGACATAGATATATCAGAGATACCCAAAGATTTTATTTTATTA
  CCAACACATCCTTATCAAATCAATGTGTTGCGACAGCATCCACAGTATATGCAATATAGT
  GAACAAGGTTTAATAAAAGACCTTGGCGTTTCCGGTGATTTAGTGTACCCGACGTCTTCG
  GTTAGAACTGTATTTTCAAAAGCATTAAACATTTATTTAAAATTACCGATACACGTTAAA
  ATTACTAATTTTATACGTACGAATGATCTTGAACAAATTGAACGGACAATTGATGCCGCG
  CAAGTTATCGCATCAGTCAAAGATGAGGTTGAAACACCCCATTTTAAATTGATGTTTGAA
  GAAGGATATCGTGCATTGTTACCGAATCCATTAGGGCAAACAGTTGAACCTGAAATGGAT
  TTATTAACAAATAGTGCCATGATTGTTCGTGAAGGGATACCGAATTACCATGCTGATAAA
  GATATTCATGTATTGGCGTCATTATTTGAAACGATGCCTGATTCACCGATCTCTAAGTTA
  GCACAAGTGATTGAGCAAAGTGGTTTAGCACCAGAAGCATGGCTTGAATGTTATTTGGAT
  CGTACATTATTGCCGATATTAAAGTTGTTTAGTAACACAGGCATTAGTCTAGAAGCACAT
  GTACAAAATACATTAATTGAATTAAAAGATGGCATACCCGACGTATGCTTTGTCAGAGAT
  CTTGAAGGCATTTGTCTATCTAGAACGATTGCTACTGAAAAACAGCTTGTGCCAAATGTT
  GTGGCAGCATCAAGCCCTGTTGTATATGCACATGATGAAGCATGGCATCGTCTTAAATAT
  TATGTTGTAGTAAATCACTTAGGACATTTAGTATCAACTATTGGTAAAGCAACTAGAAAT
  GAAGTTGTGTTATGGCAACTTGTAGCGCATCGTCTTATGACTTGGAAAAAAGAATACGCG
  AATAACGCAGTATTTGTTGACTGTGTAGAAGATTTATATCAAACGCCGACCATTGCGGCT
  AAAGCGAATTTGATGAGTAAATTGAATGATTGTGGTGCAAACCCTATTTATACACATATA
  CCAAATCCAATTTGTTATAACAAGGAGGTATCGTATTGTGAATCAAACAATTCTTAA
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  1560
  1620
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  1737
  

⊟Protein

⊟General

• locus tag: SA_RS00735 [old locus tag: SA0116 ]
• symbol: SA_RS00735
• description: IucA/IucC family siderophore biosynthesis protein
• length: 578
• theoretical pI: 5.69444
• theoretical MW: 66017.8
• GRAVY: -0.251038

⊟Function

• TIGRFAM:
• TheSEED: see SA0116
• PFAM:
  PKinase (CL0016) IucA_IucC; IucA / IucC family (PF04183; HMM-score: 174.1)
  and 3 more
  no clan defined FhuF; Ferric iron reductase FhuF-like transporter (PF06276; HMM-score: 97.9)
  Ubiquitin (CL0072) ForC_N; Formin C, N-terminal domain (PF21573; HMM-score: 13.7)
  THBO-biosyn (CL0334) FolB; Dihydroneopterin aldolase (PF02152; HMM-score: 10.5)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9419
  • Cytoplasmic Membrane Score: 0.0346
  • Cell wall & surface Score: 0.0002
  • Extracellular Score: 0.0234
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.004695
  • TAT(Tat/SPI): 0.00016
  • LIPO(Sec/SPII): 0.000525
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 447102630 NCBI
• RefSeq: WP_001179886 NCBI
• UniProt: see SA0116

⊟Additional information (user-provided)

⊟Protein sequence

• MQNKELIQHAAYAAIERILNEYFREENLYQVPPQNHQWSIQLSELETLTGEFRYWSAMGHHMYHPEVWLIDGKSKKITTYKEAIARILQHMAQSADNQTAVQQHMAQIMSDIDNSIHRTARYLQSNTIDYVEDRYIVSEQSLYLGHPFHPTPKSASGFSEADLEKYAPECHTSFQLHYLAVHQDVLLTRYVEGKEDQVEKVLYQLADIDISEIPKDFILLPTHPYQINVLRQHPQYMQYSEQGLIKDLGVSGDLVYPTSSVRTVFSKALNIYLKLPIHVKITNFIRTNDLEQIERTIDAAQVIASVKDEVETPHFKLMFEEGYRALLPNPLGQTVEPEMDLLTNSAMIVREGIPNYHADKDIHVLASLFETMPDSPISKLAQVIEQSGLAPEAWLECYLDRTLLPILKLFSNTGISLEAHVQNTLIELKDGIPDVCFVRDLEGICLSRTIATEKQLVPNVVAASSPVVYAHDEAWHRLKYYVVVNHLGHLVSTIGKATRNEVVLWQLVAHRLMTWKKEYANNAVFVDCVEDLYQTPTIAAKANLMSKLNDCGANPIYTHIPNPICYNKEVSYCESNNS

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator: Fur* see SA0116

⊟Additional information (user-provided)

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Additional information (user-provided)

⊟Other information (user-provided)

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications