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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS02180 [old locus tag: SA0381 ]
  • pan locus tag?: SAUPAN002102000
  • symbol: SA_RS02180
  • pan gene symbol?: —
  • synonym:
  • product: NAD(P)-dependent oxidoreductase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS02180 [old locus tag: SA0381 ]
  • symbol: SA_RS02180
  • product: NAD(P)-dependent oxidoreductase
  • replicon: chromosome
  • strand: -
  • coordinates: 439785..440630
  • length: 846
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (439785..440630) NCBI
  • BioCyc: SA_RS02180 BioCyc
  • MicrobesOnline: see SA0381

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAATATTATGTTAACAGGTGCTACAGGTCATTTAGGCACACATATTACAAATCAAGCC
    ATTGCAAATCACATAGATCATTTTCACATTGGTGTTAGAAATGTTGAGAAAGTTCCAGAT
    GATTGGCGTGGAAAAGTTTCTGTTCGACAATTAGATTATTTTAATCAAGAAAGCATGGTA
    GAAGCATTTAAAGGAATGGATACCGTTGTGTTTATTCCAAGTATTATCCATCCATCATTC
    AAACGTATTCCTGAAGTGGAAAATTTAGTATATGCGGCAAAGCAGAGCGGCGTTGCTCAT
    ATCATTTTCATAGGTTATTACGCAGATCAGCATAATAATCCATTCCATATGAGCCCTTAT
    TTCGGATATGCATCACGTTTATTGTCAACAAGTGGCATTGATTATACGTATGTAAGAATG
    GCAATGTACATGGATCCACTTAAACCCTATTTACCAGAATTGATGAATATGCATAAACTG
    ATTTATCCAGCTGGTGATGGTCGTATTAATTATATTACTAGAAATGATATTGCTAGAGGT
    GTCATTGCTATTATTAAAAATCCAGATACTTGGGGCAAACGCTATTTATTATCAGGCTAT
    AGTTATGATATGAAAGAACTTGCTGCTATTTTATCTGAGGCATCAGGCACAGAAATTAAA
    TATGAACCCGTTTCATTAGAGACATTTGCAGAAATGTACGATGAACCTAAAGGCTTTGGT
    GCATTATTGGCATCAATGTACCACGCAGGAGCAAGAGGACTATTAGACCAAGAATCCAAT
    GATTTCAAACAATTAGTCAATGATCAACCACAGACACTGCAATCATTTTTACAAGAAAAT
    ATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    846

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS02180 [old locus tag: SA0381 ]
  • symbol: SA_RS02180
  • description: NAD(P)-dependent oxidoreductase
  • length: 281
  • theoretical pI: 6.28363
  • theoretical MW: 31857.1
  • GRAVY: -0.235943

⊟Function[edit | edit source]

  • TIGRFAM:
    ergot alkaloid biosynthesis protein, AFUA_2G17970 family (TIGR03649; HMM-score: 51.3)
    and 5 more
    hopanoid-associated sugar epimerase (TIGR03466; HMM-score: 17.7)
    Hypothetical proteins Conserved TIGR01777 family protein (TIGR01777; HMM-score: 16.8)
    thioester reductase domain (TIGR01746; HMM-score: 14.5)
    NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family (TIGR04180; HMM-score: 13.6)
    UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase (TIGR04130; EC 4.2.1.-,5.1.3.-; HMM-score: 10.9)
  • TheSEED: see SA0381
  • PFAM:
    NADP_Rossmann (CL0063) NAD_binding_10; NAD(P)H-binding (PF13460; HMM-score: 80.7)
    NmrA; NmrA-like family (PF05368; HMM-score: 71)
    and 4 more
    Epimerase; NAD dependent epimerase/dehydratase family (PF01370; HMM-score: 22.2)
    3Beta_HSD; 3-beta hydroxysteroid dehydrogenase/isomerase family (PF01073; HMM-score: 12.7)
    RmlD_sub_bind; RmlD substrate binding domain (PF04321; HMM-score: 12.7)
    NAD_binding_4; Male sterility protein (PF07993; HMM-score: 11.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.02996
    • TAT(Tat/SPI): 0.000693
    • LIPO(Sec/SPII): 0.002276
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNIMLTGATGHLGTHITNQAIANHIDHFHIGVRNVEKVPDDWRGKVSVRQLDYFNQESMVEAFKGMDTVVFIPSIIHPSFKRIPEVENLVYAAKQSGVAHIIFIGYYADQHNNPFHMSPYFGYASRLLSTSGIDYTYVRMAMYMDPLKPYLPELMNMHKLIYPAGDGRINYITRNDIARGVIAIIKNPDTWGKRYLLSGYSYDMKELAAILSEASGTEIKYEPVSLETFAEMYDEPKGFGALLASMYHAGARGLLDQESNDFKQLVNDQPQTLQSFLQENI

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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