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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS02425 [old locus tag: SA0426 ]
  • pan locus tag?: SAUPAN002182000
  • symbol: SA_RS02425
  • pan gene symbol?: —
  • synonym:
  • product: N-acetyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS02425 [old locus tag: SA0426 ]
  • symbol: SA_RS02425
  • product: N-acetyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 486933..487418
  • length: 486
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (486933..487418) NCBI
  • BioCyc: SA_RS02425 BioCyc
  • MicrobesOnline: see SA0426

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGACAAATAATGACACCATCATGTTACGACATTATGTCCCACAAGATTATTCGATGTTA
    GAAGCTTTTCAATTAAGTGAAAGTGATTTGAAGTTTGTTAAAACGCCAGAGGAAAATATT
    ACAGCTGCAATGTCTGATAATGAAAGGTATCCCATCGTTGTAATGGATGGCAGGCAATGT
    GTGGCCTTTTTTACATTACATCGTGGAAAAGGGGTCGCACCATTTAGCGATAACCAAGAT
    GCAGTATTTTTCAGGTCATTTAGTGTTGATCAACGTTATCGTAATAGAGGAATAGGTAAA
    GTGGTAATGGAAAAATTGGCGTCATTTATCACTTCAACATTTCAGGATATTAATGAGATT
    GTGTTAACGGTTAATACTGACAATCCACATGCCATGGCACTTTATCGCCAACAAGGATAT
    CAATATATGGGAGATAGTATGTTCATCGGAAGACCTGTTCATATTATGGCGTTAACTATA
    AAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    486

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS02425 [old locus tag: SA0426 ]
  • symbol: SA_RS02425
  • description: N-acetyltransferase
  • length: 161
  • theoretical pI: 6.51482
  • theoretical MW: 18494
  • GRAVY: -0.248447

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 37.7)
    and 3 more
    UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (TIGR03585; EC 2.3.1.202; HMM-score: 24.9)
    GNAT-family acetyltransferase TIGR03103 (TIGR03103; HMM-score: 18)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs mycothiol synthase (TIGR03448; EC 2.3.1.189; HMM-score: 13.6)
  • TheSEED: see SA0426
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 41)
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 34.9)
    and 7 more
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 30.5)
    FR47; FR47-like protein (PF08445; HMM-score: 21.5)
    Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 17)
    Acetyltransf_8; Acetyltransferase (GNAT) domain (PF13523; HMM-score: 16.3)
    Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 15.3)
    Acetyltransf_CG; GCN5-related N-acetyl-transferase (PF14542; HMM-score: 15.1)
    Acetyltransf_15; Putative acetyl-transferase (PF17013; HMM-score: 14.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003815
    • TAT(Tat/SPI): 0.000171
    • LIPO(Sec/SPII): 0.00045
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTNNDTIMLRHYVPQDYSMLEAFQLSESDLKFVKTPEENITAAMSDNERYPIVVMDGRQCVAFFTLHRGKGVAPFSDNQDAVFFRSFSVDQRYRNRGIGKVVMEKLASFITSTFQDINEIVLTVNTDNPHAMALYRQQGYQYMGDSMFIGRPVHIMALTIK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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