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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS07375 [old locus tag: SA1304 ]
  • pan locus tag?: SAUPAN003932000
  • symbol: SA_RS07375
  • pan gene symbol?:
  • synonym:
  • product: heptaprenyl pyrophosphate synthase subunit A

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS07375 [old locus tag: SA1304 ]
  • symbol: SA_RS07375
  • product: heptaprenyl pyrophosphate synthase subunit A
  • replicon: chromosome
  • strand: -
  • coordinates: 1509707..1510279
  • length: 573
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (1509707..1510279) NCBI
  • BioCyc: SA_RS07375 BioCyc
  • MicrobesOnline: see SA1304

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGGAAACAACTGTTAGCAAATTGGAAAGACAAATAGAAGAAAGATTAAAGGGTGTATCA
    GAATATGAATCCATTAATATTAATCATCGGTTAGGTAAGTTACTTGATTCATATGATATT
    CCAGATGTTGCCAAAGTAGCATGCCTCACAATTGACACATCAATGAGACACCTTGATGAC
    ATTACATATAATCATTTGTCTAAACATTCCATTTTGATTGGAGATTTAATTAGTGCACAT
    TTTTATACGCTACTAGCAGAAATCAATGATTTATCATTTCAAAATGAAATTAGTAAAGCA
    ATTGTTGAAATTAATGAATTGAAATCTTCATTACATCATCAAGCTTTAAATGATTATGAA
    ATTTCTCAAGCAATAGTAAAAATTGAAACACTTTTCCCATATATTACGTTATCTCATTTC
    GGTATCAATATTGATGAGTCGGAAATATATAATTATTTATTTGAAGATATGTCTGATTAC
    TATCCATCATACTTCAAGAAATATAATCAAAGTGAAGTAAAGCATTACTTACACGATATC
    CAAAAAAGTTATTTAAAAAGTAGAGGTAATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    573

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS07375 [old locus tag: SA1304 ]
  • symbol: SA_RS07375
  • description: heptaprenyl pyrophosphate synthase subunit A
  • length: 190
  • theoretical pI: 5.27182
  • theoretical MW: 22157.8
  • GRAVY: -0.376316

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SA1304
  • PFAM:
    Terp_synthase (CL0613) HEPPP_synt_1; Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 (PF07307; HMM-score: 34.7)
    and 1 more
    YqbG (CL0643) DUF3199; Protein of unknown function (DUF3199) (PF11436; HMM-score: 8.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003372
    • TAT(Tat/SPI): 0.000409
    • LIPO(Sec/SPII): 0.00047
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • METTVSKLERQIEERLKGVSEYESININHRLGKLLDSYDIPDVAKVACLTIDTSMRHLDDITYNHLSKHSILIGDLISAHFYTLLAEINDLSFQNEISKAIVEINELKSSLHHQALNDYEISQAIVKIETLFPYITLSHFGINIDESEIYNYLFEDMSDYYPSYFKKYNQSEVKHYLHDIQKSYLKSRGN

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]