PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS10530 [old locus tag: SA1835 ]
• pan locus tag^?: SAUPAN005255000
• symbol: SA_RS10530
• pan gene symbol^?: int
• synonym:
• product: site-specific integrase

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS10530 [old locus tag: SA1835 ]
• symbol: SA_RS10530
• product: site-specific integrase
• replicon: chromosome
• strand: +
• coordinates: 2071100..2072272
• length: 1173
• essential: no DEG

⊟Accession numbers

• Location: NC_002745 (2071100..2072272) NCBI
• BioCyc: SA_RS10530 BioCyc
• MicrobesOnline: see SA1835

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
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  ATGGCAAGTTATGAAAAACGCGGAAATACATGGCGCTATCGTATATCACTAGGAAAAGAC
  GCAGAAACGGGCAAATATAAATATATTTCAAACTCAGGTTTTAAACGCAAATCAGACGCT
  AAACATCACGCTGAAATGGTTGAGCGTCAATTAAGAAATGGCGATTATATCGCACCGTCC
  ACATCTACATTTAAACAGGTTGCTGACGATTGGATATCACAATATGCTAACGAAGTAAAA
  GTAAGTAGTGTCAGAGCACGCGAGAAAGCCATACATCATGCTATAGAACGCTTTAAGAAC
  AAACCAATACAAACTATCAAAAAACACGATTATCAACGTTTTGTAAACGATATAAGCATA
  CAGTATAGCAAGAATTATGTTGATAGCATTGTAACCTCTACAAATATGATATTTAAGTAC
  GCTTATGATATGAAATTAATAAGAATATTGCCTAGCGAGGGTATTAAACGACCTAAAAAG
  AAAGTTAGTGTGGAAGAATTAGAAGATACTGAGATACATAAAAAGTTTCTTGAAAAAGAT
  GAATTATTTCAATTTCTGGAAATTGCCAAAAATCACCATTCGCCACAAAATAGCTTTGAA
  GTGTTTTATACATTAGCATATACAGGCATGCGTGCAGGTGAATTATTGGCATTGAAGTGG
  TCTGATATAGACTTTGAGAATAACACAATCAATATTACAAAGACTTATTACAATCCGAAT
  AACAATAAAAAGCAATATCAAATACTTACGCCAAAAACTGAAAGCTCAATCGGAAAAATT
  TCAGTTGATCCTCATGTGATTAAATTACTCAAAAATTATAAAGTGGATGTACAGGACACA
  TGGAAAAACGAGTTGTATGTAGATAACAATTTCGTTTTTACTGATGTTAACGGCTATCCC
  CTCGTAATTAAGAAACTACAGTTATGGATAAAAGCTATACTTAAAAAGACTAACATAACT
  AATAAACAAATAAGCACTCATTCATTTCGTCATACTCATTGCGCGTTACTTATAGAGGCT
  GGTGTGCATATTAAGGAAATACAAGAACGCTTGCGACACAAAGATATAAACACCACTATG
  AACATCTACGCTAAGATTACGAACTCATACAAAAAAGACGCTTCCCAAAAGTTTAGTAAA
  CTCATGGAAAACGTCTCAAAAGATTTATTTTAA
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⊟Protein

⊟General

• locus tag: SA_RS10530 [old locus tag: SA1835 ]
• symbol: SA_RS10530
• description: site-specific integrase
• length: 390
• theoretical pI: 10.0764
• theoretical MW: 45743
• GRAVY: -0.688205

⊟Function

• TIGRFAM:
  Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerC (TIGR02224; HMM-score: 69)
  Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerD (TIGR02225; HMM-score: 67.7)
  Genetic information processing DNA metabolism DNA replication, recombination, and repair integron integrase (TIGR02249; HMM-score: 56.3)
  Genetic information processing Mobile and extrachromosomal element functions Other integron integrase (TIGR02249; HMM-score: 56.3)
• TheSEED: see SA1835
• PFAM:
  DNA-mend (CL0382) Phage_integrase; Phage integrase family (PF00589; HMM-score: 101.2)
  and 4 more
  l-integrase_N (CL0469) Phage_int_SAM_3; Phage integrase, N-terminal SAM-like domain (PF14659; HMM-score: 41.2)
  MBD-like (CL0081) Arm-DNA-bind_4; Arm DNA-binding domain (PF14657; HMM-score: 35.9)
  no clan defined FRB_dom; FKBP12-rapamycin binding domain (PF08771; HMM-score: 13.4)
  DUF4907; Domain of unknown function (DUF4907) (PF16250; HMM-score: 12.9)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.018334
  • TAT(Tat/SPI): 0.000761
  • LIPO(Sec/SPII): 0.002141
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446101488 NCBI
• RefSeq: WP_000179343 NCBI
• UniProt: see SA1835

⊟Protein sequence

• MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHAEMVERQLRNGDYIAPSTSTFKQVADDWISQYANEVKVSSVRAREKAIHHAIERFKNKPIQTIKKHDYQRFVNDISIQYSKNYVDSIVTSTNMIFKYAYDMKLIRILPSEGIKRPKKKVSVEELEDTEIHKKFLEKDELFQFLEIAKNHHSPQNSFEVFYTLAYTGMRAGELLALKWSDIDFENNTINITKTYYNPNNNKKQYQILTPKTESSIGKISVDPHVIKLLKNYKVDVQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTNITNKQISTHSFRHTHCALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSKLMENVSKDLF

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications