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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS12405 [old locus tag: SA2161 ]
  • pan locus tag?: SAUPAN005889000
  • symbol: SA_RS12405
  • pan gene symbol?: —
  • synonym:
  • product: N-acetyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS12405 [old locus tag: SA2161 ]
  • symbol: SA_RS12405
  • product: N-acetyltransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 2428363..2428698
  • length: 336
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (2428363..2428698) NCBI
  • BioCyc: SA_RS12405 BioCyc
  • MicrobesOnline: see SA2161

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGAGTCCAAAGACGCGCGAAGCAGCTGAAAAAGGATTACCTAATGCCTTATTTACAGTA
    ACCTTGTATGATAAAGATCGGTTAATTGGTATGGGTAGAGTGATTGGCGATGGCGGAACT
    GTTTTTCAAATTGTTGATATTGCTGTTTCGAAAAGTTATCAAGGTCAAGATTACGGCAGT
    CTAATTATGGAACATATTATGAAGTATATTAAAAATGTATCTGTCGAAAGTGCATACGTT
    AGTCTGATCGCAGACTACCCAGCGGATAAATTATATGCAAAATTTGGATTTATGCCTACC
    GAACCAGATTCAGGCGGTATGTATATCAAATACTAA
    60
    120
    180
    240
    300
    336

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS12405 [old locus tag: SA2161 ]
  • symbol: SA_RS12405
  • description: N-acetyltransferase
  • length: 111
  • theoretical pI: 5.84529
  • theoretical MW: 12288.1
  • GRAVY: -0.1

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 30.1)
  • TheSEED: see SA2161
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 46.8)
    Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 41.7)
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 39.2)
    and 5 more
    Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 17.4)
    FR47; FR47-like protein (PF08445; HMM-score: 15.3)
    GNAT_acetyltr_2; GNAT acetyltransferase 2 (PF13718; HMM-score: 15.3)
    Acetyltransf_CG; GCN5-related N-acetyl-transferase (PF14542; HMM-score: 14.8)
    Acetyltransf_9; Acetyltransferase (GNAT) domain (PF13527; HMM-score: 14.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006637
    • TAT(Tat/SPI): 0.000371
    • LIPO(Sec/SPII): 0.000893
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSPKTREAAEKGLPNALFTVTLYDKDRLIGMGRVIGDGGTVFQIVDIAVSKSYQGQDYGSLIMEHIMKYIKNVSVESAYVSLIADYPADKLYAKFGFMPTEPDSGGMYIKY

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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