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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS12825 [old locus tag: SA2233 ]
  • pan locus tag?: SAUPAN005996000
  • symbol: SA_RS12825
  • pan gene symbol?: —
  • synonym:
  • product: MFS transporter

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS12825 [old locus tag: SA2233 ]
  • symbol: SA_RS12825
  • product: MFS transporter
  • replicon: chromosome
  • strand: -
  • coordinates: 2507787..2509187
  • length: 1401
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (2507787..2509187) NCBI
  • BioCyc: SA_RS12825 BioCyc
  • MicrobesOnline: see SA2233

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGGACACATCAAAACAATTTAGAGGTGACAACCGATTGCTTTTGGGTATCGTTTTAGGG
    GTTATTACCTTTTGGCTATTCGCGCAGTCACTTGTTAATCTTGTTGTCCCATTACAATCA
    ACATATAGTAGTGACGTTGGAACGATAAATATCGCTGTTAGCTTATCTGCCTTATTTGCT
    GGTTTGTTTATCGTAGGTGCTGGTGATGTTGCTGATAAATTTGGTCGCGTCAAAATTACT
    TATGTAGGATTGATATTAAATGTTGTAGGTTCATTACTCATCATCATTACACCTTTGCCA
    GCATTTTTAATTATAGGTAGAATAATTCAAGGTTTGTCTGCAGCATGTATTATGCCATCC
    ACACTTGCTATTATTAACGAATATTATATTGGTACAAGAAGACAACGTGCCTTAAGCTAT
    TGGTCTATTGGTTCTTGGGGTGGTAGTGGTATTTGTACGTTGTTTGGTGGCTTAATGGCT
    ACATATATAGGTTGGCGTTCAATATTTGTTGTTTCAATTCTATTAACATTATTAGCAATG
    TACTTAATCAAACATGCACCTGAGACTAAAGCAGAACCAATCAAAGGTATGAAAGCAGAA
    GCTAAAAAGTTTGACGTTATTGGTTTAGTCATTTTAGTAGTGACGATGTTAAGTTTAAAT
    GTAATCATCACACAGACGTCTCATTTTGGTTTAGTTTCACCGTTAATTCTAGGTTTAATT
    GTTGTGTTTATCTGTTCATTAGTTGGTTTTGTATATTACGAAAATAAAATAAAGCATCCA
    CTTGTTGATTTTTCAATTTTTAAAAATAGAGGATACAGTGGTGCAACTATTTCAAACTTC
    TTATTAAATGGTGTAGCAGGTGGTGCACTTATCGTTATTAACACGTATTATCAACAACAA
    TTAGGATTTAATTCTTCGCAAACGGGTTATATTTCATTAACGTATTTAATAGCAGTGTTG
    TCAATGATTCGTGTAGGTGAAAAGATTTTATCTCAACATGGTCCGAAGCGCCCACTATTA
    CTAGGAAGTGGCTTTACAGTGATTGGGTTAATCTTATTGTCGTTAACATTTTTACCAGAA
    GTGTGGTATATCATATCTAGTATAGTTGGATATTTATTGTTTGGTACTGGTTTAGGATTA
    TATGCTACACCATCAACTGATACAGCAGTTGCTAGTGCGCCAGATGATAAGTCGGGTGTT
    GCTTCAGGCGTATATAAAATGGCGTCATCATTAGGAAATGCATTTGGAGTAGCAGTATCT
    GGTACAGTTTATACTGTGTTAGCAGCTAATTTAAATTTGAACTTAGGTGGTTTCACAGGT
    ATGATGTTTAATGCCTTGCTAGCAATTGTTGCATTTTTAGTCATTTTACTATTAGTTCCT
    AAAAATCAAACGAATTTGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1401

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS12825 [old locus tag: SA2233 ]
  • symbol: SA_RS12825
  • description: MFS transporter
  • length: 466
  • theoretical pI: 9.74613
  • theoretical MW: 49810.8
  • GRAVY: 0.846352

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Toxin production and resistance drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family (TIGR00711; HMM-score: 124.5)
    Metabolism Transport and binding proteins Other drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family (TIGR00711; HMM-score: 124.5)
    and 9 more
    multidrug resistance protein (TIGR00880; HMM-score: 61.1)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids MFS transporter, aromatic acid:H+ symporter (AAHS) family (TIGR00895; HMM-score: 46.9)
    drug resistance transporter, Bcr/CflA subfamily (TIGR00710; HMM-score: 46.1)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-galactonate transporter (TIGR00893; HMM-score: 37.4)
    Metabolism Transport and binding proteins Anions Na(+)-dependent inorganic phosphate cotransporter (TIGR00894; HMM-score: 30.4)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids MFS transporter, sialate:H+ symporter (SHS) family (TIGR00891; HMM-score: 29.7)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids phosphoglycerate transporter family protein (TIGR00881; HMM-score: 24.1)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids oxalate/formate antiporter family transporter (TIGR00890; HMM-score: 20.1)
    Metabolism Transport and binding proteins Cations and iron carrying compounds cation transport protein (TIGR00898; HMM-score: 17.1)
  • TheSEED: see SA2233
  • PFAM:
    MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 160.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 14
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.066585
    • TAT(Tat/SPI): 0.002994
    • LIPO(Sec/SPII): 0.021327
  • predicted transmembrane helices (TMHMM): 14

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MDTSKQFRGDNRLLLGIVLGVITFWLFAQSLVNLVVPLQSTYSSDVGTINIAVSLSALFAGLFIVGAGDVADKFGRVKITYVGLILNVVGSLLIIITPLPAFLIIGRIIQGLSAACIMPSTLAIINEYYIGTRRQRALSYWSIGSWGGSGICTLFGGLMATYIGWRSIFVVSILLTLLAMYLIKHAPETKAEPIKGMKAEAKKFDVIGLVILVVTMLSLNVIITQTSHFGLVSPLILGLIVVFICSLVGFVYYENKIKHPLVDFSIFKNRGYSGATISNFLLNGVAGGALIVINTYYQQQLGFNSSQTGYISLTYLIAVLSMIRVGEKILSQHGPKRPLLLGSGFTVIGLILLSLTFLPEVWYIISSIVGYLLFGTGLGLYATPSTDTAVASAPDDKSGVASGVYKMASSLGNAFGVAVSGTVYTVLAANLNLNLGGFTGMMFNALLAIVAFLVILLLVPKNQTNL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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