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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS14150 [old locus tag: SA2472 ]
  • pan locus tag?: SAUPAN006435000
  • symbol: hisZ
  • pan gene symbol?: hisZ
  • synonym:
  • product: ATP phosphoribosyltransferase regulatory subunit

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS14150 [old locus tag: SA2472 ]
  • symbol: hisZ
  • product: ATP phosphoribosyltransferase regulatory subunit
  • replicon: chromosome
  • strand: -
  • coordinates: 2783489..2784307
  • length: 819
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (2783489..2784307) NCBI
  • BioCyc: SA_RS14150 BioCyc
  • MicrobesOnline: see SA2472

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    GTGAATAATTCAGAACAATTAATTGCGTTAAAAGAATCGGAAACAGCATTTTTAAAATAT
    TTTAATAAAGCGGATTATGAGTTAGTTGATTTTAGTGTGGTTGAAAAGTTGGACTGGAAA
    CAATTGAACCATGAGGATTTGCAGCAGATGGGTGAGCGAAATTTTTGGCAACATGAGCAT
    CAAATTTATGCACTTCGAAATGATTTTACAGATCAATTATTGCGTTATTACTCAATGTAT
    CCAACTGCAGCAACAAAAGTGGCATACACAGGTTTAATCATTCGGAATAATGAAGCGGCT
    GTACAAGTGGGTTTGGAAAACTATGCACCATCATTAGCGAATGTACAACAGAGCTTAAAG
    CTATTTATTCAGTTTATTCAACAGCAGTTGAGAGACAACGTGCATTTTGTTGTATTGGGA
    CATTATCAATTGCTTGATGCCTTACTCGATAAATCGTTACAAACACCAGACATACTATCA
    ATGATTGAGGAACGTAATTTATCGGGACTGGTTACATATTTGTCGACTGAACATCCAATC
    GTGCAAATCTTGAAAGAGAATACGCAACAACAATTAAATGTATTGGAACACTATATTCCA
    AATGACCATCCAGCACTCGTTGAATTAAAAATATGGGAACGTTGGTTACATACACAAGGT
    TACAAAGACATCCATTTAGATATTACTGCGCAGCCACCTAGATCCTATTACACAGGCTTA
    TTTATTCAATGTCATTTTGCTGAAAATGAATCTCGAGTTTTAACAGGTGGTTATTACAAA
    GGAAGCATCGAAGGGTTTGGATTAGGATTAACACTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    819

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS14150 [old locus tag: SA2472 ]
  • symbol: HisZ
  • description: ATP phosphoribosyltransferase regulatory subunit
  • length: 272
  • theoretical pI: 5.30976
  • theoretical MW: 31653.6
  • GRAVY: -0.330147

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Amino acid biosynthesis Histidine family ATP phosphoribosyltransferase, regulatory subunit (TIGR00443; HMM-score: 51.8)
  • TheSEED: see SA2472
  • PFAM:
    tRNA_synt_II (CL0040) tRNA-synt_His; Histidyl-tRNA synthetase (PF13393; HMM-score: 67.6)
    and 2 more
    F-box (CL0271) Elongin_A; RNA polymerase II transcription factor SIII (Elongin) subunit A (PF06881; HMM-score: 15.4)
    no clan defined Tape_meas_lam_C; Lambda phage tail tape-measure protein (Tape_meas_lam_C) (PF09718; HMM-score: 13.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001365
    • TAT(Tat/SPI): 0.000159
    • LIPO(Sec/SPII): 0.000287
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNNSEQLIALKESETAFLKYFNKADYELVDFSVVEKLDWKQLNHEDLQQMGERNFWQHEHQIYALRNDFTDQLLRYYSMYPTAATKVAYTGLIIRNNEAAVQVGLENYAPSLANVQQSLKLFIQFIQQQLRDNVHFVVLGHYQLLDALLDKSLQTPDILSMIEERNLSGLVTYLSTEHPIVQILKENTQQQLNVLEHYIPNDHPALVELKIWERWLHTQGYKDIHLDITAQPPRSYYTGLFIQCHFAENESRVLTGGYYKGSIEGFGLGLTL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CodY, HisR* see SA2472

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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