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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS07060 [old locus tag: NWMN_1250 ]
  • pan locus tag?: SAUPAN003712000
  • symbol: NWMN_RS07060
  • pan gene symbol?:
  • synonym:
  • product: secretion protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS07060 [old locus tag: NWMN_1250 ]
  • symbol: NWMN_RS07060
  • product: secretion protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1373771..1374634
  • length: 864
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (1373771..1374634) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_1250

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    TTGGATACACCGAAGAAACAACAATTTGCCTTTAATAATATACAAATGAACATGTCGAAA
    TCAGATGTTGAGAAAACATTAAATAAACCAAAAAGAGTGACATTTAATGAATATGGTACG
    AAGTGGTATACGTATTATGATGACGATTACAATAATTTTATAATGATAAGTTACATGAAA
    GATAAAGTTAATGCGTTATATACAAATCAAAATATAATCACTTCAAAATCAAAAATTAAA
    TACAATACACCTAAATCGGTTGTAAGGCAAAGATTAGGCGAACCAGAAACAGAGATTGTT
    AAAGGTAGAGTGCGTTACGAACAAAATAATAAAGAATATGATGTTTTCCATAAAAATCAC
    ATTTATACGACGGTATTTTATGATAAGCATCGACGTAATAATGTAACAGCTGTTTTACAA
    GTAAGTGATGCTATGGAAAATAGATTAAAAGAACAATATGGAGCACCATCGAAATCGCTT
    GCAGATAGTTTTGAACTACAAAATTTTGATTTAGTTAATGCTGAAAGAAAACAACATCAA
    TTATCTACATTGAAGTATTCTAAACAGAATTCTGAAACTGCACGTAAGCATAGTAAAGAT
    ATGGCCAACAATCATTATTTTGATCATACAAATTTAAAAGGTCAATCACCATTTGATCGA
    TTGAAAAAAGATGGTATTACATTTAACTCAGCCGGAGAGAATTTAGCATATGGTCAAGTT
    AGTAGTATCTATGCACATCAAGGATTAATGAATTCTATTGGTCACAGAAAAAATATTTTA
    AATGATACGTTTAAAATATTAGGTGTTGGTGTTGATTTTAATGATGAAAAACAACCTTTT
    TGGACAGAAAATTATACTGGTTAA
    60
    120
    180
    240
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    360
    420
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    840
    864

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS07060 [old locus tag: NWMN_1250 ]
  • symbol: NWMN_RS07060
  • description: secretion protein
  • length: 287
  • theoretical pI: 9.75257
  • theoretical MW: 33590.3
  • GRAVY: -0.989199

Function[edit | edit source]

  • TIGRFAM:
    uncharacterized protein, YkwD family (TIGR02909; HMM-score: 111.1)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined CAP_assoc_N; CAP-associated N-terminal (PF14504; HMM-score: 121.5)
    and 2 more
    CAP (CL0659) CAP; Cysteine-rich secretory protein family (PF00188; HMM-score: 56.4)
    PepSY (CL0320) SmpA_OmlA; SmpA / OmlA family (PF04355; HMM-score: 11.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.067607
    • TAT(Tat/SPI): 0.001575
    • LIPO(Sec/SPII): 0.004808
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MDTPKKQQFAFNNIQMNMSKSDVEKTLNKPKRVTFNEYGTKWYTYYDDDYNNFIMISYMKDKVNALYTNQNIITSKSKIKYNTPKSVVRQRLGEPETEIVKGRVRYEQNNKEYDVFHKNHIYTTVFYDKHRRNNVTAVLQVSDAMENRLKEQYGAPSKSLADSFELQNFDLVNAERKQHQLSTLKYSKQNSETARKHSKDMANNHYFDHTNLKGQSPFDRLKKDGITFNSAGENLAYGQVSSIYAHQGLMNSIGHRKNILNDTFKILGVGVDFNDEKQPFWTENYTG

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]