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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL0902 [new locus tag: SACOL_RS04630 ]
  • pan locus tag?: SAUPAN002864000
  • symbol: SACOL0902
  • pan gene symbol?: —
  • synonym:
  • product: pathogenicity island protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL0902 [new locus tag: SACOL_RS04630 ]
  • symbol: SACOL0902
  • product: pathogenicity island protein
  • replicon: chromosome
  • strand: +
  • coordinates: 913868..914446
  • length: 579
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGAAAACTGAATCGTACTTTAAAGAATACAACCAATTTGTAATAGATCAACAAAAGGCT
    ATACAAGAATTGAAACAAGAGCGTAATGCATTGGAGAGTAAAATAAAGATAGATAAGTCC
    ACATATAAACAGTTAATCATGGATGGACAAGATGATAAAGCAGATAACCTATATCAAGCA
    ACAGATGCTGATGAAAAGAAACTAAAAGCACTTAATAAACGCTTAGAGACAAAGAAAAGT
    GTGTCGAAAGAAGTTAAATATCAAAAGACAATTGAATTATTAAAACATCAAAGCGAGTTG
    TCATCATTATACGAATCAGAAAAGCAATCAGCTTTAGGTAAATTAAAAAAAGTAGTCGAT
    GCATATAATGAGATCATTGATGAAATAGAAGATATTAATGATAGATATGAAGATGAGCAT
    CAGCAATATGCGAGTATTTATAGTCAAGAACAATTATATGATGATAAAGAGGCTAGGGAA
    GCATTGAATGGCTACTTTAGAGAAAATATATTTACATCATATATTAATGGTAATGATTTG
    CCATACGAACACAATAACAAGTTGTTTTTAAAACGTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    579

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL0902 [new locus tag: SACOL_RS04630 ]
  • symbol: SACOL0902
  • description: pathogenicity island protein
  • length: 192
  • theoretical pI: 5.07976
  • theoretical MW: 22804.2
  • GRAVY: -1.125

⊟Function[edit | edit source]

  • TIGRFAM:
    WXG100 family type VII secretion target (TIGR03930; HMM-score: 13.9)
    Cellular processes Cellular processes Cell division cell division protein FtsL (TIGR02209; HMM-score: 13)
    and 2 more
    two transmembrane protein (TIGR04527; HMM-score: 10.4)
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage major capsid protein, HK97 family (TIGR01554; HMM-score: 6.8)
  • TheSEED  :
    • Hypothetical SAV0796 homolog in superantigen-encoding pathogenicity islands SaPI
    Phages, Prophages, Transposable elements, Plasmids Pathogenicity islands Staphylococcal pathogenicity islands SaPI  Hypothetical SAV0796 homolog in superantigen-encoding pathogenicity islands SaPI
  • PFAM:
    no clan defined CAC1F_C; Voltage-gated calcium channel subunit alpha, C-term (PF16885; HMM-score: 12)
    AB_hydrolase (CL0028) BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal (PF08840; HMM-score: 11.5)
    no clan defined DUF16; Protein of unknown function DUF16 (PF01519; HMM-score: 10.4)
    SlyX; SlyX (PF04102; HMM-score: 10.2)
    and 6 more
    P-loop_NTPase (CL0023) AAA_23; AAA domain (PF13476; HMM-score: 9.3)
    no clan defined DUF501; Protein of unknown function (DUF501) (PF04417; HMM-score: 8.9)
    IncA; IncA protein (PF04156; HMM-score: 8.7)
    DUF5082; Domain of unknown function (DUF5082) (PF16888; HMM-score: 8.7)
    Flagellin_N; Bacterial flagellin N-terminal helical region (PF00669; HMM-score: 8.5)
    CorA; CorA-like Mg2+ transporter protein (PF01544; HMM-score: 5.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00572
    • TAT(Tat/SPI): 0.000455
    • LIPO(Sec/SPII): 0.001189
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKTESYFKEYNQFVIDQQKAIQELKQERNALESKIKIDKSTYKQLIMDGQDDKADNLYQATDADEKKLKALNKRLETKKSVSKEVKYQKTIELLKHQSELSSLYESEKQSALGKLKKVVDAYNEIIDEIEDINDRYEDEHQQYASIYSQEQLYDDKEAREALNGYFRENIFTSYINGNDLPYEHNNKLFLKR

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization: Cytoplasmic [1]
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int J Med Microbiol: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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