NCBI: 26-AUG-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus N315
- locus tag: SA2124 [new locus tag: SA_RS12205 ]
- pan locus tag?: SAUPAN005820000
- symbol: fosB
- pan gene symbol?: fosB
- synonym:
- product: fosfomycin resistance protein FosB
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SA2124 [new locus tag: SA_RS12205 ]
- symbol: fosB
- product: fosfomycin resistance protein FosB
- replicon: chromosome
- strand: +
- coordinates: 2389328..2389747
- length: 420
- essential: no DEG other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 1125051 NCBI
- RefSeq: NP_375446 NCBI
- BioCyc: see SA_RS12205
- MicrobesOnline: 104472 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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361ATGTTAAAATCTATTAATCATATATGCTTTTCAGTCAGAAATTTAAACGATTCAATACAT
TTTTATAGAGATATTTTACTTGGGAAATTGCTATTGACTGGTAAAAAAACTGCTTATTTT
GAGCTTGCAGGCCTATGGATTGCTTTAAATGAAGAAAAAGATATACCACGTAATGAAATT
CACTTTTCATATACACATATAGCTTTCACTATAGATGACAGCGAATTTAAATATTGGCAT
CAGAGGTTAAAAGATAATAACGTGAATATTTTAGAAGGAAGAGTTAGAGATATTAGAGAT
AGACAATCAATTTACTTTACTGACCCTGATGGTCATAAGCTAGAATTACATACTGGCACA
CTTGAGAACAGATTAAATTATTATAAAGAGGCTAAACCACATATGACATTTTACAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SA2124 [new locus tag: SA_RS12205 ]
- symbol: FosB
- description: fosfomycin resistance protein FosB
- length: 139
- theoretical pI: 8.43846
- theoretical MW: 16647.8
- GRAVY: -0.591367
⊟Function[edit | edit source]
- reaction: EC 2.5.1.-? ExPASy
- ⊞TIGRFAM: Energy metabolism Other lactoylglutathione lyase (TIGR00068; EC 4.4.1.5; HMM-score: 26.1)Central intermediary metabolism Amino sugars lactoylglutathione lyase (TIGR00068; EC 4.4.1.5; HMM-score: 26.1)and 5 more
- TheSEED :
- Fosfomycin resistance protein FosB
- ⊞PFAM: Glyoxalase (CL0104) Glyoxalase; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily (PF00903; HMM-score: 50.6)and 1 more
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors: Mg2+
- effectors:
⊟Localization[edit | edit source]
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MLKSINHICFSVRNLNDSIHFYRDILLGKLLLTGKKTAYFELAGLWIALNEEKDIPRNEIHFSYTHIAFTIDDSEFKYWHQRLKDNNVNILEGRVRDIRDRQSIYFTDPDGHKLELHTGTLENRLNYYKEAKPHMTFYK
⊟Experimental data[edit | edit source]
- experimentally validated: data available for NCTC8325
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available