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NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus N315
- locus tag: SA_RS12540 [old locus tag: SA2186 ]
- pan locus tag?: SAUPAN005930000
- symbol: SA_RS12540
- pan gene symbol?: nasF
- synonym:
- product: uroporphyrinogen-III C-methyltransferase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
⊟Accession numbers[edit | edit source]
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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961ATGTCTGTAGATAAATATGGCAAGGTTTACTTGATAGGTGCGGGACCAGGTAATCCGAAT
TATTTGACTAAAAAGGCTGAGCGTTTAATACGTGAAGCGGATGTTATACTATATGATCGA
TTAGTGAATCCGTTAATTTTACAATATGCGAATTTGACTACTGAAATTATCGATGTTGGT
AAAAAGCCGTATGCAAAACACATTCAGCAAGAAAAAATAAATGAATGTATCGTGGAAGCA
GCACGTCGATATAACAAGGTTGTGAGGCTTAAAGGTGGCGACCCAGCAATATTTGGACGA
GTTCAAGAAGAAGTTGACACACTAAACAACTTTAATATTGCGTTTGAAATTGTACCTGGT
GTGACATCTGCGAGTGCTGCAGTTGCTACGATGCAAACAGGATTAACGATGCGTGCTGTT
GCTAAGAGTGTGACATTTTCTACAGGTCACTTTAAAGATTCAGAAGAAAATGAAGTAGAT
GTCAACGCTTTAGTAAATGGTGGTACGTTGGCGATATATATGGGAGTTAAACGTTTAGGG
AAAATTATCGCCCAGATACAACAGTACACAGATATTGATTATCCGATAGCGATTGTCTTT
CAAGCATCGTGTTTTAACGAGTTTGTTGTTAAGGGGCGTTTAAGTAATATTGTTGGGAAA
CTGGAGCATTACGCAATTGAGGCGAAACCAGGTATATGTATTATAGGCGAAGTAGTGGGT
TATACTGAAAATGTCTCAACAACTTCTAATCCGACTCAGCAATTTTATGTAGTAAGTGGT
TCTAGACATGACGCCCTTATGCTCTGTGAACATTTATATGACGAAGGTTATGGCTGTTTG
CTAAACCCAAATGATACATCGAATGGCACATATCATTCGTCGCAATATGATTACTATGAT
GCATTTATTAAGCAGCAAGAAAATGTAACATATATTTCAACCGATCGTGCAGATGCTAAT
ACAGTGTTATGTCACTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SA_RS12540 [old locus tag: SA2186 ]
- symbol: SA_RS12540
- description: uroporphyrinogen-III C-methyltransferase
- length: 325
- theoretical pI: 5.64381
- theoretical MW: 36008.6
- GRAVY: -0.159385
⊟Function[edit | edit source]
- ⊞TIGRFAM: Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin uroporphyrinogen-III C-methyltransferase (TIGR01469; EC 2.1.1.107; HMM-score: 292.4)and 5 more
- TheSEED: see SA2186
- PFAM: no clan defined TP_methylase; Tetrapyrrole (Corrin/Porphyrin) Methylases (PF00590; HMM-score: 154.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MSVDKYGKVYLIGAGPGNPNYLTKKAERLIREADVILYDRLVNPLILQYANLTTEIIDVGKKPYAKHIQQEKINECIVEAARRYNKVVRLKGGDPAIFGRVQEEVDTLNNFNIAFEIVPGVTSASAAVATMQTGLTMRAVAKSVTFSTGHFKDSEENEVDVNALVNGGTLAIYMGVKRLGKIIAQIQQYTDIDYPIAIVFQASCFNEFVVKGRLSNIVGKLEHYAIEAKPGICIIGEVVGYTENVSTTSNPTQQFYVVSGSRHDALMLCEHLYDEGYGCLLNPNDTSNGTYHSSQYDYYDAFIKQQENVTYISTDRADANTVLCH
⊟Experimental data[edit | edit source]
- experimentally validated: data available for NCTC8325
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: NreC*, Rex* see SA2186
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available