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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS10135 [old locus tag: NWMN_1773 ]
  • pan locus tag?: SAUPAN001709000
  • symbol: NWMN_RS10135
  • pan gene symbol?:
  • synonym:
  • product: cell wall hydrolase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS10135 [old locus tag: NWMN_1773 ]
  • symbol: NWMN_RS10135
  • product: cell wall hydrolase
  • replicon: chromosome
  • strand: -
  • coordinates: 1984284..1986182
  • length: 1899
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (1984284..1986182) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATGGGATTACCTAATCCAAAAAACAGAAAACCTACAGCTAGTGAAGTAGTAGAGTGGGCT
    TTGTATATCGCTAAAAATAAAATAGCTATTGATGTACCTGGTTCTGGAATGGGAGCACAA
    TGCTGGGATTTACCTAATTATTTACTCGATAAATATTGGGGGTTTAGAACATGGGGAAAT
    GCTGATGCTATGGCTCAAAAATCCAATTATAGAGGTAGAGATTTCAAGATAATTAGAAAT
    ACAAAAGATTTTGTACCACAACCAGGCGACTGGGGTGTTTGGACTGGTGGTTGGGCAGGA
    CATGTAAACATTGTAGTGGGACCATGCACAAAAGACTATTGGTATGGCGTAGATCAAAAC
    TGGTATACAAATAACGCAACAGGAAGTCCACCTTATAAAATTAAACACTCTTATCATGAT
    GGACCAGGTGGAGGGGTTAAATATTTTGTTAGACCACCATATCATCCAGACAAAACTACA
    CCGGCACCTAAACCAGAAGATGATAGTGATGATAACGAAAAAAATAATAAAAAAGTTCCA
    ATTTGGAAAGATGTAACAACTATAAAGTACACTATTTCTAGCCAAGAGGTTAATTATCCA
    GAATATATTTATCACTTTATAGTAGAAGGTAATCGACGACTCGAAAAACCTAAAGGAATA
    ATGATTAGAAACGCACAAACGATGAGCTCGGTAGAAAGTTTATATAACAGTAGGAAGAAA
    TACAAACAGGATGTAGAATATCCCCACTTTTATGTTGATAGACATAATATTTGGGCACCT
    AGAAGAGCTGTATTTGAAGTTCCTAATGAACCTGATTATATAGTTATAGACGTATGTGAA
    GATTATAGTGCGAGTAAAAATGAATTTATTTTTAATGAGATTCACGCAATGGTTGTAGCT
    GTAGATATGATGGCCAAATATGAGATACCTCTAAGTATTGAAAATTTAAAAGTAGACGAC
    AGCATTTGGCGTTCAATGTTGGAACATGTTAATTGGAATATGATTGACAACGGTGTTCCT
    CCTAAAGATAAATACGAAGCATTAGAAAAGGCATTACTTAATATATTTAAAAACAGAGAA
    AAATTATTAAATTCTATAACTAAGCCAACAGTAACAAAATCTAGAATAAAAGTTATGGTA
    GATAATAAAAACGCTGATATAGCGAATGTAAGAGACTCGTCACCAACAGCCAACAATGGT
    TCGGCATCTAAACAACCGCAGATCATAACAGAAACGAGTCCTTATACATTCAAACAAGCA
    CTGGATAAACAAATGGCAAGAGGTAACCCGAAAAAATCTAATGCTTGGGGTTGGGCTAAC
    GCTACACGAGCACAAACGAGTTCAGCAATGAATGTTAAACGAATATGGGAAAGTAACACG
    CAGTGCTACCAAATGCTTAATTTAGGCAAGTATCAAGGTGTTTCAGTTAGCGCACTTAAT
    AAGATACTTAAAGGTAAGGGAACATTGAATAATCAAGGTAAAGCGTTCGCAGAAGCTTGT
    AAAAAGCACAGCATTAATGAAATTTATTTAATCGCGCATGCTTTCTTAGAAAGTGGATAT
    GGAACAAGTAACTTCGCTAACGGAAAAGATGGAGTATACAACTACTTCGGCATTGGTGCT
    TACGACAACAATCCTAACTACGCAATGACGTTTGCAAGGAATAAAGGTTGGACATCTCCA
    GCAAAAGCAATCATGGGCGGTGCTAGCTTCGTAAGAAAGGATTACATCAATAAAGGTCAA
    AACACATTGTACCGAATTAGATGGAATCCTAAGAATCCAGCTACCCACCAATACGCTACT
    GCTATAGAGTGGTGCCAACATCAAGCAAGTACAATCGCTAAGTTATATAAACAAATCGGC
    TTAAAAGGTATCTACTTCACAAGGGATAAATATAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1899

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_RS10135 [old locus tag: NWMN_1773 ]
  • symbol: NWMN_RS10135
  • description: cell wall hydrolase
  • length: 632
  • theoretical pI: 9.77316
  • theoretical MW: 71975.1
  • GRAVY: -0.684335

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    flagellar rod assembly protein/muramidase FlgJ (TIGR02541; HMM-score: 22.5)
  • TheSEED:
  • PFAM:
    Lysozyme (CL0037) Glucosaminidase; Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase (PF01832; HMM-score: 49.2)
    Peptidase_CA (CL0125) CHAP; CHAP domain (PF05257; HMM-score: 29.9)
    no clan definedINCENP_ARK-bind; Inner centromere protein, ARK binding region (PF03941; HMM-score: 12.7)
    Lysozyme (CL0037) SLT_2; Transglycosylase SLT domain (PF13406; HMM-score: 12.5)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.09
    • Cellwall Score: 0.18
    • Extracellular Score: 9.72
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.167
    • Ymax_pos: 11
    • Cmax: 0.133
    • Cmax_pos: 39
    • Smax: 0.329
    • Smax_pos: 2
    • Smean: 0.271
    • D: 0.208
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446446154 NCBI
  • RefSeq: WP_000524009 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MGLPNPKNRKPTASEVVEWALYIAKNKIAIDVPGSGMGAQCWDLPNYLLDKYWGFRTWGNADAMAQKSNYRGRDFKIIRNTKDFVPQPGDWGVWTGGWAGHVNIVVGPCTKDYWYGVDQNWYTNNATGSPPYKIKHSYHDGPGGGVKYFVRPPYHPDKTTPAPKPEDDSDDNEKNNKKVPIWKDVTTIKYTISSQEVNYPEYIYHFIVEGNRRLEKPKGIMIRNAQTMSSVESLYNSRKKYKQDVEYPHFYVDRHNIWAPRRAVFEVPNEPDYIVIDVCEDYSASKNEFIFNEIHAMVVAVDMMAKYEIPLSIENLKVDDSIWRSMLEHVNWNMIDNGVPPKDKYEALEKALLNIFKNREKLLNSITKPTVTKSRIKVMVDNKNADIANVRDSSPTANNGSASKQPQIITETSPYTFKQALDKQMARGNPKKSNAWGWANATRAQTSSAMNVKRIWESNTQCYQMLNLGKYQGVSVSALNKILKGKGTLNNQGKAFAEACKKHSINEIYLIAHAFLESGYGTSNFANGKDGVYNYFGIGAYDNNPNYAMTFARNKGWTSPAKAIMGGASFVRKDYINKGQNTLYRIRWNPKNPATHQYATAIEWCQHQASTIAKLYKQIGLKGIYFTRDKYK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS10135 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]