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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS14660 [old locus tag: NWMN_2553 ]
  • pan locus tag?: SAUPAN006390000
  • symbol: NWMN_RS14660
  • pan gene symbol?: sasA
  • synonym:
  • product: serine-rich repeat glycoprotein adhesin SasA

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS14660 [old locus tag: NWMN_2553 ]
  • symbol: NWMN_RS14660
  • product: serine-rich repeat glycoprotein adhesin SasA
  • replicon: chromosome
  • strand: -
  • coordinates: 2817522..2824337
  • length: 6816
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (2817522..2824337) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

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    ATGAGTAAAAGACAGAAAGCATTTCATGACAGCTTAGCAAACGAAAAAACAAGAGTAAGA
    CTTTATAAATCTGGAAAAAATTGGGTAAAATCCGGAATTAAAGAAATAGAAATGTTCAAA
    ATTATGGGGCTACCATTTATTAGTCATAGTTTAGTGAGTCAAGATAATCAAAGCATTAGT
    AAAAAAATGACGGGATACGGACTGAAAACTACGGCGGTTATTGGTGGTGCATTCACGGTA
    AATATGTTGCATGACCAGCAAGCTTTTGCGGCTTCTGATGCACCATTAACTTCTGAATTA
    AACACACAAAGTGAAACAGTAGGTAATCAAAACTCAACGACAATCGAAGCATCAACATCA
    ACAGCCGATTCCACAAGTGTAACGAAAAATAGTAGTTCGGTACAAACATCAAATAGTGAC
    ACAGTCTCAAGTGAAAAGTCTGAAAAGGTCACTTCGACAACTAATAGTACAAGCAATCAA
    CAAGAGAAATTGACATCTACATCAGAATCAACATCCTCAAAGAATACTACATCAAGTTCT
    GATACTAAATCTGTAGCTTCAACTTCAAGTACAGAACAACCAATTAATACATCAACAAAT
    CAAAGTACTGCATCAAATAACACTTCACAAAGCACAACGCCATCTTCGGTCAACTTAAAC
    AAAACTAGCACAACGTCAACTAGCACCGCACCAGTAAAACTTCGAACTTTCAGTCGCTTA
    GCTATGTCAACATTTGCGTCAGCAGCGACGACAACCGCAGTAACTGCTAATACAATTACA
    GTTAATAAAGATAACTTAAAACAATATATGACAACGTCAGGTAATGCTACCTATGATCAA
    AGTACCGGTATTGTGACGTTAACACAGGATGCATACAGCCAAAAAGGTGCTATTACATTA
    GGAACACGTATTGACTCTAATAAGAGTTTTCATTTTTCTGGAAAAGTAAATTTAGGTAAC
    AAATATGAAGGGCATGGAAATGGTGGAGATGGTATCGGTTTTGCCTTTTCACCAGGTGTA
    TTAGGTGAAACAGGGTTAAACGGTGCCGCAGTAGGTATTGGTGGCTTAAGTAACGCATTT
    GGCTTCAAATTGGATACGTATCACAATACATCTAAACCAAATTCAGCTGCAAAGGCGAAT
    GCTGACCCATCTAATGTAGCTGGTGGAGGTGCGTTTGGTGCATTTGTAACAACAGATAGT
    TATGGTGTTGCGACAACGTATACATCAAGTTCAACAGCTGATAATGCTGCGAAGTTAAAT
    GTTCAACCTACAAATAACACGTTCCAAGATTTTGATATTAACTATAATGGTGATACAAAG
    GTTATGACTGTCAAATATGCAGGTCAAACATGGACACGTAATATTTCAGATTGGATTGCG
    AAAAGTGGTACGACCAACTTTTCATTATCAATGACAGCCTCAACAGGTGGCGCGACAAAT
    TTACAACAAGTACAATTTGGAACATTCGAATATACAGAGTCTGCTGTTACACAAGTGAGA
    TACGTTGATGTAACAACAGGTAAAGATATTATTCCACCAAAAACATATTCAGGAAATGTT
    GATCAAGTCGTGACAATCGATAATCAGCAATCTGCATTGACTGCTAAAGGATATAACTAC
    ACGTCCGTCGATAGTTCATATGCGTCAACTTATAATGATACAAATAAAACTGTAAAAATG
    ACGAATGCTGGACAATCAGTGACATATTATTTTACTGATGTAAAAGCACCAACTGTAACT
    GTAGGCAATCAAACCATAGAAGTGGGTAAAACAATGAATCCTATTGTATTGACTACAACG
    GATAATGGTACTGGGACTGTGACAAATACAGTTACAGGATTACCAAGCGGATTAAGTTAC
    GATAGTGCAACGAATTCAATCATTGGGACACCAACAAAAATTGGTCAATCAACAGTGACA
    GTTGTGTCTACTGACCAAGCAAATAACAAATCGACGACAACTTTTACAATAAATGTTGTG
    GATACGACAGCACCAACAGTGACACCAATAGGAGATCAATCATCAGAAGTGTATTCACCA
    ATATCCCCGATTAAAATTGCTACGCAAGATAACAGTGGAAATGCGGTGACGAATACAGTG
    ACTGGATTGCCATCCGGACTAACATTTGATAGTACAAATAATACTATTAGTGGTACACCA
    ACAAACATTGGTACAAGTACTATATCAATCGTTTCTACAGATGCGAGCGGTAACAAAACG
    ACGACAACTTTTAAATATGAAGTAACAAGAAATAGCATGAGTGATTCCGTATCAACATCA
    GGAAGTACACAACAATCTCAAAGTGTGTCAACAAGTAAAGCTGACTCACAAAGTGCATCA
    ACGAGTACATCAGGATCGATTGTGGTATCTACATCAGCTAGTACCTCGAAATCGACAAGT
    GTAAGCCTATCTGATTCTGTGAGTGCATCTAAGTCATTAAGCACATCTGAAAGTAATAGT
    GTATCAAGCTCAACAAGCACAAGTTTAGTGAATTCACAAAGTGTATCATCAAGCATGTCG
    GATTCAGCTAGTAAATCAACATCATTAAGCGATTCTATTTCAAACTCTAGCAGTACTGAA
    AAATCCGAAAGTCTATCAACAAGTACATCTGATTCATTGCGTACATCAACATCACTCAGT
    GACTCATTAAGTATGAGTACATCAGGAAGCTTGTCTAAGTCACAAAGCTTATCAACGAGT
    ATATCAGGGTCGTCTAGTACATCAGCATCATTAAGTGACAGTACATCGAATGCAATTAGT
    ACATCAACATCATTGAGCGAGTCAGCTAGCACCTCGGACTCTATCAGTATTTCAAATAGC
    ATAGCCAACTCTCAAAGTGCGTCAACAAGCAAATCAGATTCACAAAGTACATCAATATCA
    TTAAGTACAAGTGATTCAAAATCGATGAGTACATCAGAATCATTGAGCGATTCGACGAGC
    ACAAGTGGTTCTGTTTCTGGATCACTAAGCATAGCAGCATCACAAAGTGTCTCAACAAGT
    ACATCAGACTCGATGAGTACTTCAGAGATAGTAAGTGACTCTATCAGTACAAGTGGGTCA
    TTATCTGCATCAGACAGTAAATCAATGTCCGTAAGTAGTTCAATGAGCACGTCTCAGTCA
    GGTAGTACATCAGAATCATTAAGTGATTCACAAAGTACATCTGATTCTGATAGTAAGTCA
    TTATCACAAAGTACTAGTCAATCAGGTTCAACAAGTACATCAACGTCGACAAGTGCTTCA
    GTACGTACTTCGGAATCACAAAGTACGTCTGGTTCAATGAGTGCAAGTCAATCCGATTCA
    ATGAGCATATCAACGTCGTTTAGTGATTCAACGAGTGATAGCAAATCAGCATCAACTGCA
    TCAAGTGAATCAATATCACAAAGTGCTTCTACGAGCACATCTGGTTCGGTAAGTACTTCG
    ACATCGTTAAGTACAAGTAATTCAGAACGTACATCAACATCTATGAGTGATTCCACAAGC
    TTAAGTACATCAGAGTCTGATTCAATAAGTGAATCAACGTCAACGAGCGACTCTATAAGT
    GAAGCAATATCTGCTTCAGAGAGCACGTTTATATCATTAAGTGAATCAAATAGTACTAGC
    GATTCAGAATCACAAAGTGCATCTGCCTTTTTAAGTGAATCATTAAGTGAAAGTACGTCT
    GAATCAACATCAGAGTCAGTGAGTAGTTCGACAAGTGAGAGTACGTCATTATCAGACAGT
    ACATCAGAATCTGGTAGCACATCAACATCATTAAGTAATTCAACAAGTGGTAGTACGTCC
    ATTTCAACATCGACAAGTATCAGTGAATCAACGTCAACGTTTAAGAGCGAGAGTGTTTCA
    ACATCACTGAGTATGTCAACGAGTACAAGTTTGTCTGACTCTACAAGTTTGTCAACATCA
    TTAAGTGATTCCACAAGTGATAGTAAGTCTGATTCATTAAGTACATCAATGTCGACAAGT
    GATTCAATCAGTACAAGTAAATCTGATTCCATTAGTACATCCACATCATTAAGTGGTTCT
    ACAAGTGAAAGTGAATCCGACTCAACATCATCAAGTGAAAGTAAATCCGATTCAACATCA
    ATGAGCATAAGTATGTCTCAATCAACATCAGGAAGTACAAGTACGTCAACGAGTACAAGT
    TTGTCTGACTCAACGAGTACATCATTGTCACTAAGTGCCTCAATGAATCAAAGCGGAGTA
    GACTCAAACTCAGCAAGCCAAAGTGCCTCAAACTCAACAAGTACAAGCACGAGCGAATCC
    GATTCACAAAGCACATCATCATATACAAGTCAGTCAACAAGCCAAAGTGAATCCACATCG
    ACATCAACGTCACTAAGCGATTCAACAAGTATATCTAAAAGTACGAGTCAATCAGGTTCG
    GTAAGCACATCAGCGTCATTAAGTGGTTCAGAGAGTGAATCTGATTCACAAAGTATCTCA
    ACAAGTGCAAGTGAGTCAACATCAGAAAGTGCGTCAACATCACTCAGTGACTCAACAAGT
    ACAAGTAACTCAGGATCAGCAAGTACGTCAACATCGCTCAGTAACTCAGCAAGCGCAAGT
    GAATCCGATTTGTCGTCAACATCTTTAAGTGATTCAACATCTGCGTCAATGCAAAGCAGT
    GAATCCGATTCACAAAGCACATCAGCATCATTAAGTGATTCGCTAAGTACATCAACTTCA
    AACCGCATGTCGACCATTGCAAGTTTATCTACATCGGTAAGTACATCAGAGTCTGGCTCA
    ACATCAGAAAGTACAAGTGAATCCGATTCAACATCAACATCATTAAGCGATTCACAAAGC
    ACATCAAGAAGTACAAGTGCATCAGGATCAGCAAGTACATCAACATCAACAAGTGACTCT
    CGTAGTACATCAGCTTCAACTAGTACTTCGATGCGTACAAGTACTAGTGATTCACAAAGT
    ATGTCGCTTTCGACAAGTACATCAACAAGTATGAGTGATTCAACGTCATTATCTGATAGT
    GTTAGTGATTCAACATCAGACTCAACAAGTGCGAGTACATCTGGTTCGATGAGTGTGTCT
    ATATCGTTAAGTGATTCGACAAGTACATCAACATCGGCTAGTGAAGTAATGAGCGCAAGC
    ATATCTGATTCACAAAGTATGTCAGAATCTGTAAATGATTCAGAAAGTGTAAGTGAATCT
    AATTCTGAAAGTGACTCTAAATCGATGAGTGGCTCAACAAGTGTCAGTGATTCTGGCTCA
    TTGAGCGTCTCAACGTCATTAAGAAAATCAGAAAGTGTAAGCGAGTCAAGTTCATTGAGT
    TGCTCACAATCGATGAGCGATTCAGTAAGCACAAGCGATTCGTCATCATTAAGTGTATCG
    ACGTCACTAAGAAGTTCAGAAAGCGTGAGTGAATCTGATTCATTAAGTGATTCAAAATCA
    ACAAGTGGTTCGACTTCAACAAGTACATCTGGTTCATTGAGTACCTCAACATCATTAAGT
    GGTTCAGAAAGCGTAAGCGAGTCTACCTCGCTAAGTGATTCAATATCAATGAGTGATTCT
    ACTAGTACAAGTGACTCCGACTCATTAAGTGGATCAATATCTTTAAGTGGTTCCACAAGT
    CTTAGCACTTCGGATTCATTAAGTGATTCAAAATCATTGAGTAGCTCGCAAAGTATGAGT
    GGATCAGAATCAACGTCAACAAGTGTGAGCGATTCGCAGTCAAGCTCAACAAGTAATAGT
    CAATTTGACTCTATGAGCATCAGTGCATCAGAAAGCGACTCAATGTCTACAAGTGATTCG
    TCTAGCATCAGTGGATCAAATTCAACGAGTACATCACTTTCAACATCTGACTCAATGAGC
    GGAAGCGTATCAGTTTCAACATCGACAAGTTTAAGTGACTCAATATCAGGTTCAACAAGT
    GTAAGTGACTCGAGCTCAACAAGCACATCTACATCATTAAGTGATTCAATGTCACAAAGC
    CAGTCAACAAGTACAAGTGCATCTGGTTCCTTAAGTACATCGATATCAACATCAATGTCA
    ATGAGTGCTAGTACATCGTCATCACAAAGCACATCGGTGTCGACATCATTATCAACATCA
    GACAGTATCAGTGATTCTACTTCAATAAGTATCAGTGGTTCACAAAGTACAGTAGAATCA
    GAATCTACAAGTGATTCAACTTCTATCAGTGACTCAGAATCATTGAGTACATCAGATTCA
    GACTCGACATCGACAAGTACATCGGACTCAACAAGTGGTTCAACTTCAACAAGCATATCT
    GAATCATTAAGTACGTCTGGTTCAGGTTCAACGAGCGTATCTGACTCAACATCAATGAGT
    GAATCTAATTCATCGAGTGTTTCAATGTCACAAGACAAATCCGACTCAACATCAATTAGT
    GACTCAGAATCAGTGTCAACAAGCACATCAACGTCATTGAGCACATCCGATTCGACAAGC
    ACATCCGAATCACTGAGTACATCTATGTCTGGTTCACAAAGCATTTCTGACTCAACATCA
    ACAAGTATGTCCGGCTCAACAAGTACATCTGAATCTAACTCAATGCATCCGTCAGACTCA
    ATGAGTATGCATCATACTCACAGCACGAGCACATCTCGCTTATCAAGTGAAGCAACAACG
    AGCACGAGTGAATCTCAGTCTACATTAAGTGCAACATCTGAAGTGACTAAACATAATGGC
    ACACCAGCACAAAGTGAAAAAAGATTGCCAGATACAGGTGACTCAATAAAACAAAATGGA
    TTACTAGGTGGCGTTATGACATTATTAGTTGGTTTAGGTTTAATGAAGAGAAAGAAAAAG
    AAAGATGAAAATGATCAAGATGATTCTCAAGCATAA
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Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_RS14660 [old locus tag: NWMN_2553 ]
  • symbol: NWMN_RS14660
  • description: serine-rich repeat glycoprotein adhesin SasA
  • length: 2271
  • theoretical pI: 3.97105
  • theoretical MW: 228015
  • GRAVY: -0.539102

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    KxYKxGKxW signal peptide (TIGR03715; HMM-score: 28.4)
    Cell structureCell envelopeOtherLPXTG cell wall anchor domain (TIGR01167; HMM-score: 24.4)
  • TheSEED:
  • PFAM:
    no clan definedGram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 34.2)
    E-set (CL0159) HYR; HYR domain (PF02494; HMM-score: 13.1)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.152
    • Ymax_pos: 14
    • Cmax: 0.13
    • Cmax_pos: 59
    • Smax: 0.308
    • Smax_pos: 3
    • Smean: 0.227
    • D: 0.181
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 445966678 NCBI
  • RefSeq: WP_000044533 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MSKRQKAFHDSLANEKTRVRLYKSGKNWVKSGIKEIEMFKIMGLPFISHSLVSQDNQSISKKMTGYGLKTTAVIGGAFTVNMLHDQQAFAASDAPLTSELNTQSETVGNQNSTTIEASTSTADSTSVTKNSSSVQTSNSDTVSSEKSEKVTSTTNSTSNQQEKLTSTSESTSSKNTTSSSDTKSVASTSSTEQPINTSTNQSTASNNTSQSTTPSSVNLNKTSTTSTSTAPVKLRTFSRLAMSTFASAATTTAVTANTITVNKDNLKQYMTTSGNATYDQSTGIVTLTQDAYSQKGAITLGTRIDSNKSFHFSGKVNLGNKYEGHGNGGDGIGFAFSPGVLGETGLNGAAVGIGGLSNAFGFKLDTYHNTSKPNSAAKANADPSNVAGGGAFGAFVTTDSYGVATTYTSSSTADNAAKLNVQPTNNTFQDFDINYNGDTKVMTVKYAGQTWTRNISDWIAKSGTTNFSLSMTASTGGATNLQQVQFGTFEYTESAVTQVRYVDVTTGKDIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQSVTYYFTDVKAPTVTVGNQTIEVGKTMNPIVLTTTDNGTGTVTNTVTGLPSGLSYDSATNSIIGTPTKIGQSTVTVVSTDQANNKSTTTFTINVVDTTAPTVTPIGDQSSEVYSPISPIKIATQDNSGNAVTNTVTGLPSGLTFDSTNNTISGTPTNIGTSTISIVSTDASGNKTTTTFKYEVTRNSMSDSVSTSGSTQQSQSVSTSKADSQSASTSTSGSIVVSTSASTSKSTSVSLSDSVSASKSLSTSESNSVSSSTSTSLVNSQSVSSSMSDSASKSTSLSDSISNSSSTEKSESLSTSTSDSLRTSTSLSDSLSMSTSGSLSKSQSLSTSISGSSSTSASLSDSTSNAISTSTSLSESASTSDSISISNSIANSQSASTSKSDSQSTSISLSTSDSKSMSTSESLSDSTSTSGSVSGSLSIAASQSVSTSTSDSMSTSEIVSDSISTSGSLSASDSKSMSVSSSMSTSQSGSTSESLSDSQSTSDSDSKSLSQSTSQSGSTSTSTSTSASVRTSESQSTSGSMSASQSDSMSISTSFSDSTSDSKSASTASSESISQSASTSTSGSVSTSTSLSTSNSERTSTSMSDSTSLSTSESDSISESTSTSDSISEAISASESTFISLSESNSTSDSESQSASAFLSESLSESTSESTSESVSSSTSESTSLSDSTSESGSTSTSLSNSTSGSTSISTSTSISESTSTFKSESVSTSLSMSTSTSLSDSTSLSTSLSDSTSDSKSDSLSTSMSTSDSISTSKSDSISTSTSLSGSTSESESDSTSSSESKSDSTSMSISMSQSTSGSTSTSTSTSLSDSTSTSLSLSASMNQSGVDSNSASQSASNSTSTSTSESDSQSTSSYTSQSTSQSESTSTSTSLSDSTSISKSTSQSGSVSTSASLSGSESESDSQSISTSASESTSESASTSLSDSTSTSNSGSASTSTSLSNSASASESDLSSTSLSDSTSASMQSSESDSQSTSASLSDSLSTSTSNRMSTIASLSTSVSTSESGSTSESTSESDSTSTSLSDSQSTSRSTSASGSASTSTSTSDSRSTSASTSTSMRTSTSDSQSMSLSTSTSTSMSDSTSLSDSVSDSTSDSTSASTSGSMSVSISLSDSTSTSTSASEVMSASISDSQSMSESVNDSESVSESNSESDSKSMSGSTSVSDSGSLSVSTSLRKSESVSESSSLSCSQSMSDSVSTSDSSSLSVSTSLRSSESVSESDSLSDSKSTSGSTSTSTSGSLSTSTSLSGSESVSESTSLSDSISMSDSTSTSDSDSLSGSISLSGSTSLSTSDSLSDSKSLSSSQSMSGSESTSTSVSDSQSSSTSNSQFDSMSISASESDSMSTSDSSSISGSNSTSTSLSTSDSMSGSVSVSTSTSLSDSISGSTSVSDSSSTSTSTSLSDSMSQSQSTSTSASGSLSTSISTSMSMSASTSSSQSTSVSTSLSTSDSISDSTSISISGSQSTVESESTSDSTSISDSESLSTSDSDSTSTSTSDSTSGSTSTSISESLSTSGSGSTSVSDSTSMSESNSSSVSMSQDKSDSTSISDSESVSTSTSTSLSTSDSTSTSESLSTSMSGSQSISDSTSTSMSGSTSTSESNSMHPSDSMSMHHTHSTSTSRLSSEATTSTSESQSTLSATSEVTKHNGTPAQSEKRLPDTGDSIKQNGLLGGVMTLLVGLGLMKRKKKKDENDQDDSQA

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS14660 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]