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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0041 [new locus tag: SA_RS00350 ]
  • pan locus tag?: SAUPAN000106000
  • symbol: xylR
  • pan gene symbol?: xylR
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA0041 [new locus tag: SA_RS00350 ]
  • symbol: xylR
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 49752..50882
  • length: 1131
  • essential: no DEG

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATAAATGATAATGAAAAAAGAGTGCTAAGGGAAATTTATAACCATCATAATATTTCGCGT
    ACTCAAATATCTAAAAATCTTGAGATTAATAAGGCAACGATTTCTAGTATTTTGAATAAG
    TTAAAGTATAAATCTCTTGTTAATGAGGTTGGTGAGGGTGATAGCACGAAGAGTGGTGGT
    AGAAAACCTATTCTTCTGAAGGTTAATCATCTTTATGGTTATTTTATTTCTTTGGATTTA
    ACTTATAGTTCTGTTGAAGTGATGTACAATTATTTTGATGGTAATGTCATTAAGCATGAA
    TCTTATGATTTACCTGATGAAAAGGTTAGTAGTATATTAAGCATAATAAAAAAACATATT
    GATATTCAGGAGAAACTTGATACTTATAACGGACTATTAGGTGTGTCTGTTTCTATACAT
    GGAGTTGTGGATAATGAGCAGCATGTGACATATTTACCATTCCATGAAACTGAAGGAATT
    TCAATTGCTAAGAAAATAAAAGAAATTACTAATGTTCCAGTCGTAGTTGAAAATGAAGCG
    AATCTTTCAGCGTTATATGAACGTAATTTTAATCATAATTTATCCTACAATAATCTTATT
    GCTTTAAGTATACATAAAGGTATTGGTGCTGGGCTTATTATTAATAATCAATTGTATCGT
    GGTGCAAATGGGGAAGCGGGTGAAATTGGAAAAACACTTGTCTCAAAAGTTAGCGATAAT
    GTGGAGATCTTTCATAAGATTGAAGATATTTTTTCACAAGAAGCTTTACTGCATAATTTA
    AGTAATCAACTAAATGAGAAGATGACGCTTAGCAAATTAATTCAATTTTATAATGAAAAA
    AATCCAGTCGTAGTTGAAGAAATGGAACAATTTATAAATAAAATTGCTGTTTTAATACAT
    AATTTAAACACCCAGTTTAATCCGAATGCAATTTACATTAACTGTCCATTGTTCAATGAA
    ATGCCTGAAATATTAGAAGCAATTAAGAACCAGTTCAAACAATATTCACGTAACGAAATT
    CAAATAAAGTTAACATCTAATGTCAAATTTGCAACTTTGCTAGGTGGTACATTAGCAATT
    ATCCAAAAAGTACTACAGATTAATGATATTTACTTAGATATAAAAGCATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1131

Protein[edit source | edit]

Protein Data Bank: 4IJA

General[edit source | edit]

  • locus tag: SA0041 [new locus tag: SA_RS00350 ]
  • symbol: XylR
  • description: hypothetical protein
  • length: 376
  • theoretical pI: 6.71195
  • theoretical MW: 42671.5
  • GRAVY: -0.22234

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Unknown functionGeneralROK family protein (putative glucokinase) (TIGR00744; HMM-score: 76.2)
    Signal transductionRegulatory functionsDNA interactionsCRISPR locus-related DNA-binding protein (TIGR01884; HMM-score: 16.5)
    Signal transductionRegulatory functionsDNA interactionsTyrR family helix-turn-helix domain (TIGR04381; HMM-score: 12.4)
  • TheSEED:  
    Putative ROK-family transcriptional regulator 
  • PFAM:
    Actin_ATPase (CL0108) ROK; ROK family (PF00480; HMM-score: 117.5)
    HTH (CL0123) MarR; MarR family (PF01047; HMM-score: 27.3)
    MarR_2; MarR family (PF12802; HMM-score: 21.5)
    HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 20.5)
    Fe_dep_repress; Iron dependent repressor, N-terminal DNA binding domain (PF01325; HMM-score: 19.7)
    TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 19.3)
    TFIIE_alpha; TFIIE alpha subunit (PF02002; HMM-score: 17.1)
    HTH_27; Winged helix DNA-binding domain (PF13463; HMM-score: 16.7)
    Penicillinase_R; Penicillinase repressor (PF03965; HMM-score: 13.8)
    HTH_36; Helix-turn-helix domain (PF13730; HMM-score: 13.7)
    HTH_3; Helix-turn-helix (PF01381; HMM-score: 13.3)
    Rrf2; Transcriptional regulator (PF02082; HMM-score: 12.9)
    Sigma70_r4; Sigma-70, region 4 (PF04545; HMM-score: 12.6)
    HTH_5; Bacterial regulatory protein, arsR family (PF01022; HMM-score: 12.4)
    no clan definedTraC_F_IV; F pilus assembly Type-IV secretion system for plasmid transfer (PF11130; HMM-score: 11.3)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.127
    • Ymax_pos: 54
    • Cmax: 0.113
    • Cmax_pos: 54
    • Smax: 0.211
    • Smax_pos: 43
    • Smean: 0.128
    • D: 0.128
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 15925748 NCBI
  • RefSeq: NP_373281 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MNDNEKRVLREIYNHHNISRTQISKNLEINKATISSILNKLKYKSLVNEVGEGDSTKSGGRKPILLKVNHLYGYFISLDLTYSSVEVMYNYFDGNVIKHESYDLPDEKVSSILSIIKKHIDIQEKLDTYNGLLGVSVSIHGVVDNEQHVTYLPFHETEGISIAKKIKEITNVPVVVENEANLSALYERNFNHNLSYNNLIALSIHKGIGAGLIINNQLYRGANGEAGEIGKTLVSKVSDNVEIFHKIEDIFSQEALLHNLSNQLNEKMTLSKLIQFYNEKNPVVVEEMEQFINKIAVLIHNLNTQFNPNAIYINCPLFNEMPEILEAIKNQFKQYSRNEIQIKLTSNVKFATLLGGTLAIIQKVLQINDIYLDIKA

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]