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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS02575 [old locus tag: SACOL0510 ]
  • pan locus tag?: SAUPAN002182000
  • symbol: SACOL_RS02575
  • pan gene symbol?:
  • synonym:
  • product: N-acetyltransferase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS02575 [old locus tag: SACOL0510 ]
  • symbol: SACOL_RS02575
  • product: N-acetyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 509927..510412
  • length: 486
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (509927..510412) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGACAAATAATGACACCATCATGTTACGACATTATGTCCCACAAGATTATTCGATGTTA
    GAAGCTTTTCAATTAAGTGAAAGTGATTTGAAGTTTGTTAAAACGCCAGAGGAAAATATT
    ACAGCTGCAATGTCTGATAATGAAAGGTATCCCATCGTTGTAATGGATGGCAGGCAATGT
    GTGGCCTTTTTTACATTACATCGTGGAAAAGGGGTCGCACCATTTAGCGATAACCAAGAT
    GCAGTATTTTTCAGGTCATTTAGTGTTGATCAACGTTATCGTAATAGAGGAATAGGTAAA
    GTGGTAATGGAAAAATTGGCGTCATTTATCACTTCAACATTTCAGGATATTAATGAGATT
    GTGTTAACGGTTAATACTGACAATCCACATGCCATGGCACTTTATCGCCAACAAGGATAT
    CAATATATGGGAGATAGTATGTTCGTCGGAAGACCTGTTCATATTATGGCGTTAACTATA
    AAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    486

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS02575 [old locus tag: SACOL0510 ]
  • symbol: SACOL_RS02575
  • description: N-acetyltransferase
  • length: 161
  • theoretical pI: 6.51482
  • theoretical MW: 18480
  • GRAVY: -0.250311

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingProtein synthesisRibosomal proteins: synthesis and modificationribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 37.7)
    UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (TIGR03585; EC 2.3.1.202; HMM-score: 24.8)
    GNAT-family acetyltransferase TIGR03103 (TIGR03103; HMM-score: 18)
    MetabolismBiosynthesis of cofactors, prosthetic groups, and carriersGlutathione and analogsmycothiol synthase (TIGR03448; EC 2.3.1.189; HMM-score: 13.6)
  • TheSEED:
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 41)
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 35.2)
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 30.5)
    FR47; FR47-like protein (PF08445; HMM-score: 21.8)
    Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 17.1)
    Acetyltransf_8; Acetyltransferase (GNAT) domain (PF13523; HMM-score: 16.3)
    Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 15.3)
    Acetyltransf_CG; GCN5-related N-acetyl-transferase (PF14542; HMM-score: 15.1)
    Acetyltransf_15; Putative acetyl-transferase (PF17013; HMM-score: 14.5)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.108
    • Ymax_pos: 46
    • Cmax: 0.11
    • Cmax_pos: 23
    • Smax: 0.157
    • Smax_pos: 41
    • Smean: 0.094
    • D: 0.103
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446105814 NCBI
  • RefSeq: WP_000183669 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MTNNDTIMLRHYVPQDYSMLEAFQLSESDLKFVKTPEENITAAMSDNERYPIVVMDGRQCVAFFTLHRGKGVAPFSDNQDAVFFRSFSVDQRYRNRGIGKVVMEKLASFITSTFQDINEIVLTVNTDNPHAMALYRQQGYQYMGDSMFVGRPVHIMALTIK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS02575 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]