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NCBI: 02-MAR-2017

⊟Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS09010 [old locus tag: SACOL1762 ]
  • pan locus tag?: SAUPAN004365000
  • symbol: SACOL_RS09010
  • pan gene symbol?: tpx
  • synonym:
  • product: 2-Cys peroxiredoxin

⊟Genome View[edit source | edit]

⊟Gene[edit source | edit]

⊟General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS09010 [old locus tag: SACOL1762 ]
  • symbol: SACOL_RS09010
  • product: 2-Cys peroxiredoxin
  • replicon: chromosome
  • strand: -
  • coordinates: 1801857..1802351
  • length: 495
  • essential: unknown

⊟Accession numbers[edit source | edit]

  • Location: NC_002951 (1801857..1802351) NCBI
  • MicrobesOnline:

⊟Phenotype[edit source | edit]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGACTGAAATAACATTCAAAGGTGGACCAATCCACTTAAAAGGTCAACAAATTAATGAA
    GGTGATTTTGCACCTGATTTTACAGTGTTAGATAATGACTTAAATCAAGTAACATTAGCA
    GATTATGCTGGTAAAAAGAAATTAATTAGTGTGGTACCATCAATTGATACAGGTGTTTGT
    GATCAGCAGACTCGCAAATTCAACTCTGATGCTTCTAAAGAAGAGGGGATTGTGCTTACA
    ATTTCAGCAGACTTACCATTCGCACAAAAAAGATGGTGCGCTTCAGCAGGTTTAGACAAT
    GTCATTACATTAAGTGACCACCGTGACTTATCATTTGGTGAAAACTATGGCGTTGTTATG
    GAAGAACTTCGCTTATTAGCTCGTGCAGTATTTGTATTAGATGCAGATAATAAAGTTGTT
    TATAAAGAAATCGTTAGTGAAGGTACTGATTTCCCAGATTTTGATGCTGCTTTAGCTGCA
    TACAAAAATATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    495

⊟Protein[edit source | edit]

Protein Data Bank: 3P7X

⊟General[edit source | edit]

  • locus tag: SACOL_RS09010 [old locus tag: SACOL1762 ]
  • symbol: SACOL_RS09010
  • description: 2-Cys peroxiredoxin
  • length: 164
  • theoretical pI: 4.33649
  • theoretical MW: 18005.2
  • GRAVY: -0.134146

⊟Function[edit source | edit]

  • reaction:
    EC 1.11.1.15?  ExPASy
    Peroxiredoxin2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH
  • TIGRFAM:
    Cellular processesCellular processesDetoxificationperoxiredoxin (TIGR03137; EC 1.11.1.15; HMM-score: 25.2)
    Cellular processesCellular processesAdaptations to atypical conditionsperoxiredoxin (TIGR03137; EC 1.11.1.15; HMM-score: 25.2)
  • TheSEED:
  • PFAM:
    Thioredoxin (CL0172) Redoxin; Redoxin (PF08534; HMM-score: 89.4)
    and 1 more
    AhpC-TSA; AhpC/TSA family (PF00578; HMM-score: 64.6)

⊟Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

⊟Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.111
    • Ymax_pos: 69
    • Cmax: 0.117
    • Cmax_pos: 25
    • Smax: 0.15
    • Smax_pos: 21
    • Smean: 0.092
    • D: 0.104
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit source | edit]

  • GI: 446058398 NCBI
  • RefSeq: WP_000136253 NCBI
  • UniProt:

⊟Protein sequence[edit source | edit]

  • MTEITFKGGPIHLKGQQINEGDFAPDFTVLDNDLNQVTLADYAGKKKLISVVPSIDTGVCDQQTRKFNSDASKEEGIVLTISADLPFAQKRWCASAGLDNVITLSDHRDLSFGENYGVVMEELRLLARAVFVLDADNKVVYKEIVSEGTDFPDFDAALAAYKNI

⊟Experimental data[edit source | edit]

  • experimentally validated: no data available

⊟Expression & Regulation[edit source | edit]

⊟Operon[edit source | edit]

  • SACOL_RS09010 no polycistronic organisation predicted

⊟Regulation[edit source | edit]

  • sigma factor:
  • regulator:

⊟Transcription pattern[edit source | edit]

⊟Protein synthesis (provided by Aureolib)[edit source | edit]

⊟Protein stability[edit source | edit]

  • half-life: no data available

⊟Biological Material[edit source | edit]

⊟Mutants[edit source | edit]

⊟Expression vector[edit source | edit]

⊟lacZ fusion[edit source | edit]

⊟GFP fusion[edit source | edit]

⊟two-hybrid system[edit source | edit]

⊟FLAG-tag construct[edit source | edit]

⊟Antibody[edit source | edit]

⊟Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

⊟Literature[edit source | edit]

⊟References[edit source | edit]

⊟Relevant publications[edit source | edit]

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