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04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS11195
  • pan locus tag?:
  • symbol: SACOL_RS11195
  • pan gene symbol?:
  • synonym:
  • product: lytic regulatory protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS11195
  • symbol: SACOL_RS11195
  • product: lytic regulatory protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2199850..2200941
  • length: 1092
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (2199850..2200941) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    TTGTTTACTTACTTTAAATCAGCATTTAAAAATGCTAAACCACAATTATTAATAACATTG
    ATATATGCACTTATAGCATTTGCTGTAATTGCAGTTGTATATTTACTTGCTAATTTCCAG
    CTTGCTAAGTATGCACAAACTATTGCAATTTATTCACAATTTGGGCAAAAACCACCAGTA
    GATGCATATTTAAAAGTTATCGCTGTATTACTTATAGCAGCTGTAGTTTCACTGTTTGTT
    TTAGTTCAAATTTTTATCGGAATTACAAATGTTATGAAACGAGCAATGAGTCATGAAAAA
    GTAAAATTTACCGATTTATTTATTGCATTTAAAAAAGGTAATTATTTAAAGAGCGTTCTG
    ATCGGTCTTGTATCTATAGCAATGATTATCGTTCTTTCACTTCTGACATCATTACTATAC
    AAATTATTTTCTCCAGTATCAGAAATGATTATGAATTCAGTACAATCATCATATGCAGAT
    AGTACACACCTGATTGGTATTGCTATTACAACTCAAAGCATCATAATCATTGTTGTTTTA
    TTGATTAAAGCAATTATTACTTGGTTATTGTTAATACCTATTTTCAACTTTATGACTAGT
    TTCGTTGAATCAACTAACGATAAAGTAAAAACACACTTAGCTAATGGATTTAAAGCAATG
    AAAAATGGTCAAAAAACATTTTTCAAATTTTTCATTGGAATACTATTATTAAACTTAATT
    ATTATTTTATTTAAAACACCTGTTGGTTACTTGATTTCATTTAATACGCAATCACTCTCT
    CAAAGTGTTGCAGAAAATATCATAAGAGTTTATACAGTAATGACAATTATTTTATTCGTT
    GTTATTCATGCAATCATTTTAATGGGTATCGTTCAATATTACTTAAAACGTGGTCAAAAA
    ATTACTAAAGATAAAGTAAAAACAGCTGACAAGAATAAAAAAGTTGTCACTGAACCAAAA
    AATACAAAAGTAGAAAATGATAAAGTGACAACATCTGTTGAAACAAAAACAGAAAAAGCA
    CAAGATTCATTAAATGATAATACAACAAAAACAATGACTTCAGATAAACCAGAAGACAAT
    CAACCAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1092

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS11195
  • symbol: SACOL_RS11195
  • description: lytic regulatory protein
  • length: 363
  • theoretical pI: 10.3916
  • theoretical MW: 40665.4
  • GRAVY: 0.528926

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
  • TheSEED:
  • PFAM:
    no clan definedDUF1510; Protein of unknown function (DUF1510) (PF07423; HMM-score: 15.1)
    DUF4834; Domain of unknown function (DUF4834) (PF16118; HMM-score: 15)
    MLANA; Protein melan-A (PF14991; HMM-score: 14.7)
    DUF975; Protein of unknown function (DUF975) (PF06161; HMM-score: 13.6)
    Mucin; Mucin-like glycoprotein (PF01456; HMM-score: 9.1)
    Abhydrolase_9_N; Alpha/beta-hydrolase family N-terminus (PF15420; HMM-score: 7.6)
    DHHC; DHHC palmitoyltransferase (PF01529; HMM-score: 6.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.178
    • Ymax_pos: 45
    • Cmax: 0.186
    • Cmax_pos: 45
    • Smax: 0.395
    • Smax_pos: 15
    • Smean: 0.199
    • D: 0.186
  • predicted transmembrane helices (TMHMM): 6

Accession numbers[edit source | edit]

  • GI: 446417816 NCBI
  • RefSeq: WP_000495671 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYAQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS11195 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]