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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 03-AUG-2016

Summary[edit source | edit]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_01508
  • pan locus tag?: SAUPAN003953000
  • symbol: SAOUHSC_01508
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAOUHSC_01508
  • symbol: SAOUHSC_01508
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1459227..1460141
  • length: 915
  • essential: no DEG

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGCTTAAAAAAGCAAAATTTATCTTAATGGCAACGATACTACTATCAGGATGTTCAACT
    ACCAATAACGAATCCAACAAAGAAACAAAATCTGTACCAGAAGAAATGGATGCTTCAAAA
    TATGTAGGACAAGGATTCCAACCACCTGCAGAAAAAGATGCGATTGAATTTGCAAAGAAG
    CATAAAGATAAAATTGCTAAGCGAGGCGAACAATTTTTTATGGATAACTTCGGTCTAAAA
    GTTAAAGCTACAAATGTTATAGGTAGTGGCGATGGTGTAGAAGTATTCGTGCATTGTGAT
    GACCACGACATCGTATTTAATGCGAGTATTCCATTTGATAAATCAATTATTGACAGTGAT
    AGCTCATTAAGAAGTAAGGATAAAGGTGATGATATGAGTACTTTAGTTGGTGCAGTACTC
    AGTGGGTTTGAATATCGAGCACAAAAAGAAAAATATGATAAATTATATAAATTTTTCAAA
    GATAATGAAGAGAAATATCAATATACAGGATTTACAAAAGAAGCAATTAATAAGACGCAA
    AATAGTGGTTATGAAAATGAATATTTTTATATTTCGGCCATACCTTATAATTTAGCTGAG
    TATAGAGACTATTTTGAACCATTGTTAAACAAAAGTGACAGTGAATTTTCAAAAGAATTG
    TCAAATGTTAAGAAGCAATTAAAAGATAAGTCTAAAGTTTCGGTAACTACTACTCTATTT
    AGTAAAAAAAAGAACTATACTAAAAAAAGTAACAGTGAAAATGTAATAAAAATGGCAGAA
    GAAATAAAAAAAGATAAAGAGATACCAAACGGTATAGAGCTTAGTATAAAATTTTCGGAC
    AATAAAATAAATACGGTTAAACCAAATTTTAACGGTGAAAGCACTTCAGAATATGGTGTG
    TTTGATCAAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    915

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAOUHSC_01508
  • symbol: SAOUHSC_01508
  • description: hypothetical protein
  • length: 304
  • theoretical pI: 6.80935
  • theoretical MW: 34585.6
  • GRAVY: -0.772697

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Cellular processesCellular processesSporulation and germinationsporulation lipoprotein, YhcN/YlaJ family (TIGR02898; HMM-score: 10.5)
  • TheSEED:  
    FIG01107889: hypothetical protein 
  • PFAM:
    no clan definedDUF1672; Protein of unknown function (DUF1672) (PF07901; HMM-score: 462)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 3.33
    • Cellwall Score: 3.33
    • Extracellular Score: 3.33
    • Internal Helices: 0
  • LocateP: Lipid anchored
    • Prediction by SwissProt Classification: Extracellular
    • Pathway Prediction: Sec-(SPII)
    • Intracellular Possibility: 0
    • Signal Peptide Possibility: 0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: LLSGCST
  • SignalP: Signal peptide length 28 aa
    • Ymax: 0.442
    • Ymax_pos: 28
    • Cmax: 0.278
    • Cmax_pos: 28
    • Smax: 0.945
    • Smax_pos: 6
    • Smean: 0.806
    • D: 0.584
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MLKKAKFILMATILLSGCSTTNNESNKETKSVPEEMDASKYVGQGFQPPAEKDAIEFAKKHKDKIAKRGEQFFMDNFGLKVKATNVIGSGDGVEVFVHCDDHDIVFNASIPFDKSIIDSDSSLRSKDKGDDMSTLVGAVLSGFEYRAQKEKYDKLYKFFKDNEEKYQYTGFTKEAINKTQNSGYENEYFYISAIPYNLAEYRDYFEPLLNKSDSEFSKELSNVKKQLKDKSKVSVTTTLFSKKKNYTKKSNSENVIKMAEEIKKDKEIPNGIELSIKFSDNKINTVKPNFNGESTSEYGVFDQE

Experimental data[edit source | edit]

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. Maren Depke, Stephan Michalik, Alexander Rabe, Kristin Surmann, Lars Brinkmann, Nico Jehmlich, Jörg Bernhardt, Michael Hecker, Bernd Wollscheid, Zhi Sun, Robert L Moritz, Uwe Völker, Frank Schmidt
    A peptide resource for the analysis of Staphylococcus aureus in host-pathogen interaction studies.
    Proteomics: 2015, 15(21);3648-3661
    [PubMed:26224020] [WorldCat.org] [DOI] (I p)
  2. Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet.: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit source | edit]