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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40

NCBI: 03-AUG-2016

Summary[edit source | edit]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_02182
  • pan locus tag?: SAUPAN005049000
  • symbol: SAOUHSC_02182
  • pan gene symbol?:
  • synonym:
  • product: tail length tape measure protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAOUHSC_02182
  • symbol: SAOUHSC_02182
  • product: tail length tape measure protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2044037..2048689
  • length: 4653
  • essential: no DEG

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    ATGCCTAATCCTATAGGTAATATGGTCATAAAGGTTGATTTAGATGGTTCTGGATTCAAT
    AGAGGTGTGACAGGTTTAAATAGGCAAATGAAAATGGTTTCGCGTGAGCTTTCGGCTAAT
    TTATCACAATTTTCTAGATATGATAATTCATTAGAAAAGTCGAAGATAAAAGTCGAAGGT
    TTGAGTAAAAAACAAAAAGTTCAAGCCCAGATTACTAAAGAGCTGAAAGATAGTTATGAC
    AAACTTAGTAAAGAAACTGGTGAAAACAGTGCAAAGACACAAGCTGCGGCTGCTAAATAC
    AATGAAGCTTACGCTAAATTAAACCAATATGAGCGAGAGTTAAATCAAGCCACACAAGAA
    TTAAAAGACATGCAAAGAGAGCAGAAAGCATTAAATACTGCAATGGGAAAACTTGGTACC
    AACTTTAATAATTTTGGTCCTAAACTTCAAGAAATTGGTAACAGTATGAAAAATGTAGGC
    CGTAACATGACTATGTATGTAACTGCGCCGGTGGTTGCTGGGTTTGCTGTAGCAGCTAAA
    AAAGGTATTGAATTCGATGACAGTATGAGAAAAGTTAAAGCAACTTCAGGTGCTACTGGG
    GAAGAGTTTGAAGCTTTGAAGAAAAAGGCTCGCGAAATGGGTGCAACAACAAAATTTAGT
    GCATCAGATTCGGCTGAAGCATTAAATTACATGGCACTTGCTGGTTGGGATTCTAAGCAA
    ATGATGGAAGGTTTAAGCGGAGTTATGGATTTAGCGGCAGCATCTGGCGAAGAACTGGAA
    GCAGTAAGTGACATTGTTACAGATGGACTAACGGCATTCGGTTTAAAAGCAAAGGATAGT
    GGTCATTTTGCGGACATTTTAGCACAAACTAGCTCGAAGGCAAATACGGATGTTAGAGGG
    CTCGGAGAAGCTTTTAAATATGTCGCTCCTGTAGCAGGTGCGTTAGGTTACACGATTGAA
    GATACATCTATTGCGATAGGTTTAATGAGTAATGCTGGTATCAAAGGTGAAAAAGCAGGT
    ACAGCGTTACGAACAATGTTCACCAATCTTTCAAGTCCAACTAGAGCTATGGGGAATGAA
    ATGGAACGCTTAGGAATATCTATTACAGATAGTAATGGGAAAATGATTCCTATGCGAAAG
    CTTTTAGACCAACTGAGGGAAAAATTTAAACATCTTTCAAAAGACCAACAAGCTAGTTCT
    GCAGCTACAATATTTGGTAAAGAAGCGATGTCAGGAGCATTAGCGATTATAAATGCTTCT
    GATGAAGACTATCAAAAGTTAACCAAATCTATAGATTCATCTACCGGCGCATCTAAAAGA
    ATGGCCGATACAATGGAATCTGGTTTAGGTGGGAAATTAAGAACTTTAAGGTCGCAATTA
    GAAGAACTAGCCTTAACGATTTATGACAGAATAGAACCAGCACTAAAGATTATAGTAAGT
    GCTTTTAGCAAAGTAGTGACATGGGTTACTAAATTACCAACGTCAATTCAATTAGCGGTT
    GTTGGGTTTGGATTATTTGCAGCAGTTTTAGGTCCTTTAGTTTTTATGTTCGGTTTATTT
    ATCAGCGTGATGGGGAATGCAATGACAGTTTTAGGACCCTTGTTAATAAACGTTAATAAA
    GCTGGTGGTTTATTCGCGTTTTTAAGAACTAAAATCGCATCACTTGTTAAACTATTTCCG
    ATTTTAGGTGTGTCGATATCAAGTTTAACGTTACCTATAACATTAATTGTAGGTGCATTA
    GTTGGTATTGGCATAGCTTTCTATCAAGCTTATAAACGTTCAGAAACTTTTAGAAATATT
    GTAAATCAGGCAATCTCTGGTGTAGCAAACGCATTTAAAGCAGCTAAACTAGCGTTACAA
    GGTTTCTTTGATTTATTCAAAGGTGATAGTAAAGGCGCGGTTACCCTAGAGAAGATATTT
    CCACCCGAAACTGTAGCAGGAATACAAAATGTAGTTAATACGATTAGAACAACTTTCTTT
    AAAGTAGTTGATGCAATCGTTGGTTTCGCCAAAGAGATAGGCGCTCAATTAGCCTCTTTC
    TGGAAAGAGAACGGCTCAGAAATAACACAAGCTTTGCAAAATATAGCTGGTTTCATTAAA
    GCAACCTTTGAATTTATTTTTAACTTTATTATTAAACCAATCATGTTTGCGATTTGGCAA
    GTGATGCAATTTATTTGGCCGGCGGTTAAAGCTTTGATTGTCAGCACTTGGGAAAATATC
    AAAGGTGTAATACAAGGGGCTATTAATATTATTTTGGGTATTATCAAAGTGTTCTCTAGT
    CTTTTCACAGGAAACTGGCGAGGCGTTTGGGACGGCATTGTAATGATACTGAAAGGTACT
    GTGCAGTTAATTTGGAATTTAATACAACTGTGGTTTGTAGGTAAGATTCTAGGTGTTGTT
    AGATACTTTGGTGGATTGCTTAAAGGTTTAATATCCGGTATCTGGGGTGTTATCAAAGGT
    ATTTTCACAAAATCATTATCTGCAATTTGGAATGCAACGAAAAGTATTTTTGGTTTCTTA
    TACAATAGTGTTAAATCTATTTTCACTAATATGAAAAACTGGTTATCTAGTACGTGGAAT
    AATATCAAAAGCAATACCGTCGGCAAGGCTCATTCGTTATTTACGGGTGTAAGGTCTAAA
    TTCACAAGTTTATGGAATGCGACGAAAGATATATTTACTAAATTAAGAAATTGGATGTCA
    AACATCTGGAACTCTATTAAAGATAACACGGTAGGTATAGCTGGTCGTTTGTGGGATAAA
    GTACGTAATATCTTCGGAAACATGCGTGACGGTTTAAAATCTATCATTGGTAAAATTAAA
    GATCATATCGGCGGTATGGTAGATGCTATTAAAAAAGGACTTAATAAATTAATTGAAGGC
    TTAAACTGGGTCGGTGGTAAGTTAGGTATGGATGAAATACCTAGGTTACACACTGGTACA
    GAGCACACACATACTACTACAAGATTAGTTAAGAACGGTAAGATTGCACGTGATACATTC
    GCTACAGTTGGGGATAAAGGACGTGGAAATGGTCCAAATGGTTTTAGAAATGAAATGATT
    GAATTCCCTAATGGTAAACGTGTAATCACACCTAGTACAGACACTACTGCTTATTTACCT
    AAAGGCTCAAAAGTATACAACGGTGCACAAACTTATTCAATGTTAAACGGAACGCTTCCG
    AGATTTCATTTCGGTACTACTATGTGGAAAGATATTAAATCTAGTGCATCATCGGCATTT
    AACTGGACAAAAGATCAAATAGGTAAAGGCACAAAGTGGCTTGGCGATAAAGTTGGTGAT
    GTCATGGACTTTATCGATAATCCAGGCAAACTTTTAAATTATGTACTTCAAGCGTTTGGA
    GTTGATTTCAGTTCTCTAACTAAAGGTATGGGTATTGCTGGCGATATAACAAAAGCTGCA
    TGGTCTAAGATTAAGAAAAGTGCAATCAAGTGGCTTGAGGATGCTTTCGCAGAGTCGGGT
    GATGGCGGTGTATTAGATATGAGTAAATTACGTTACTTATACGGTCACACTGCTGCTTAT
    ACACGAGAAACCGGACGCCCATTCCATGAAGGTCTGGATTTTGATTACATTTACGAACCT
    GTTCCATCAACCATTAATGGTAGAGCACAAGTTATGCCTGTTCATAATGGTGGTTATGGA
    AAATGGGTGAAAATTGTAAAGGGCGCCTTAGAAGTTATTTATGCACATTTATCTAAATAT
    AAAGTTAAAACTGGTCAACAAGTTAGGGTCGGACAGACTGTTGGTATATCGGGGAATACG
    GGGTTTAGTACAGGACCTCACTTACATTATGAGATGCGTTGGAATGGAAGACATAGAGAC
    CCGTTACCGTGGTTAAGAAAGAATAATGGGGGCGGCAAAAGTACACCCGGTGGTAATGGT
    GCAGCTAATGCTAGACGAGCTATTAAGGCTGCTCAAAATATTTTAGGAGGAAGGTATAAG
    GCGAGTTGGATTACTAACGAGATGATGCGTGTTGCGAGTCGTGAATCCAATTATACAGCT
    AATGCAGTCAATAATTGGGATAGCAACGCAAGAGCTGGTATACCTTCAAGAGGTATGTTC
    CAAATGATAGATCCTTCATTTAGAGCGTACGCAAAGTCGGGTTACAATAATCCTCTCAAC
    CCAACTCATCAAGCTATATCGGCTATGAGATATATTGTGGGTAAATGGGTACCAAGAACA
    GGCTCATGGAGAGCTGCGTTCAAACGCGCTGGTGATTACGCATATGCTACTGGTGGCAAA
    GTCTATAACGGATTGTATCACTTAGGGGAAGAAGGATATCCAGAGTGGATAATACCTACT
    GATCCAAGTAGAGCGAACGAAGCACACAAATTATTAGCTTTAGCTGCTAACGATATTGAT
    AACCGCTCTAAAAATAAGCGACCAAACAACTTACCAAATCCAAGTATAAGTAATAGTGAT
    ACAAACTATATTCATACATTGGAGAATAAACTGGATGCGGTTATTAATTGTTTGGTTAGT
    TTGGTTGAGTCTAATCAAGTTATTGCAGATAAGGATTACGAACCAGTTATTAATAAGTAT
    GTGTTTGAAGATGAGGTAAATAATTCTATCGATAAACGAGAGCGTCACGAATCTACAAGA
    GTTAGATTTAGAAGAGGAGGCACGATAATCTAA
    60
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    2160
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    4020
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    4140
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    4260
    4320
    4380
    4440
    4500
    4560
    4620
    4653

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAOUHSC_02182
  • symbol: SAOUHSC_02182
  • description: tail length tape measure protein
  • length: 1550
  • theoretical pI: 10.36
  • theoretical MW: 169957
  • GRAVY: -0.182258

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingMobile and extrachromosomal element functionsProphage functionsphage tail tape measure protein, TP901 family, core region (TIGR01760; HMM-score: 273.9)
    Cellular processesCellular processesCell divisionchromosome segregation protein SMC (TIGR02168; HMM-score: 31.8)
    Genetic information processingDNA metabolismChromosome-associated proteinschromosome segregation protein SMC (TIGR02168; HMM-score: 31.8)
    Cellular processesCellular processesCell divisionchromosome segregation protein SMC (TIGR02169; HMM-score: 25.6)
    Genetic information processingDNA metabolismChromosome-associated proteinschromosome segregation protein SMC (TIGR02169; HMM-score: 25.6)
    helix-rich protein (TIGR04523; HMM-score: 20.9)
    two transmembrane protein (TIGR04527; HMM-score: 16.6)
    WXG100 family type VII secretion target (TIGR03930; HMM-score: 8.8)
    Genetic information processingProtein synthesistRNA aminoacylationserine--tRNA ligase (TIGR00414; EC 6.1.1.11; HMM-score: 7.5)
    Genetic information processingProtein fateProtein and peptide secretion and traffickingtype I secretion membrane fusion protein, HlyD family (TIGR01843; HMM-score: 7.3)
    conserved hypothetical protein (TIGR02231; HMM-score: 7.1)
  • TheSEED:  
    Phages, Prophages, Transposable elements, PlasmidsPhages, ProphagesPhage tail proteins 2 Phage tail length tape-measure protein 
  • PFAM:
    no clan definedPhageMin_Tail; Phage-related minor tail protein (PF10145; HMM-score: 192.4)
    Hybrid (CL0105) Peptidase_M23; Peptidase family M23 (PF01551; HMM-score: 74.9)
    no clan definedDUF4200; Domain of unknown function (DUF4200) (PF13863; HMM-score: 19.7)
    Baculo_PEP_C; Baculovirus polyhedron envelope protein, PEP, C terminus (PF04513; HMM-score: 19.2)
    TMP_2; Prophage tail length tape measure protein (PF06791; HMM-score: 16.4)
    DUF1664; Protein of unknown function (DUF1664) (PF07889; HMM-score: 16.2)
    Reo_sigma (CL0326) Reo_sigmaC; Reovirus sigma C capsid protein (PF04582; HMM-score: 15.1)
    BCLiA (CL0551) APG6; Autophagy protein Apg6 (PF04111; HMM-score: 14.2)
    P-loop_NTPase (CL0023) DUF3584; Protein of unknown function (DUF3584) (PF12128; HMM-score: 13.4)
    no clan definedTup_N; Tup N-terminal (PF08581; HMM-score: 12.4)
    P-loop_NTPase (CL0023) AAA_13; AAA domain (PF13166; HMM-score: 12.4)
    Fusion_gly (CL0595) Corona_S2; Coronavirus S2 glycoprotein (PF01601; HMM-score: 12)
    no clan definedFib_alpha; Fibrinogen alpha/beta chain family (PF08702; HMM-score: 11.8)
    DUF948; Bacterial protein of unknown function (DUF948) (PF06103; HMM-score: 11.3)
    FTA4; Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 (PF13093; HMM-score: 11)
    UPF0565; Uncharacterised protein family UPF0565 (PF10561; HMM-score: 10.5)
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein (PF07926; HMM-score: 10.4)
    Exonuc_VII_L; Exonuclease VII, large subunit (PF02601; HMM-score: 9.7)
    Tropomyosin-lke (CL0452) Tropomyosin; Tropomyosin (PF00261; HMM-score: 9.6)
    no clan definedLaminin_II; Laminin Domain II (PF06009; HMM-score: 9.4)
    Snapin_Pallidin; Snapin/Pallidin (PF14712; HMM-score: 9.4)
    DUF2203; Uncharacterized conserved protein (DUF2203) (PF09969; HMM-score: 9)
    GOLD-like (CL0521) EMP24_GP25L; emp24/gp25L/p24 family/GOLD (PF01105; HMM-score: 8.9)
    no clan definedCollagen_mid; Bacterial collagen, middle region (PF15984; HMM-score: 8.6)
    Syntaxin-6_N; Syntaxin 6, N-terminal (PF09177; HMM-score: 7.3)
    Spc7; Spc7 kinetochore protein (PF08317; HMM-score: 6.8)
    ALIX_LYPXL_bnd; ALIX V-shaped domain binding to HIV (PF13949; HMM-score: 6.7)
    Prominin; Prominin (PF05478; HMM-score: 6.3)
    DUF4407; Domain of unknown function (DUF4407) (PF14362; HMM-score: 6)
    IFT57; Intra-flagellar transport protein 57 (PF10498; HMM-score: 5.4)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.03
    • Cytoplasmic Membrane Score: 8.77
    • Cellwall Score: 0.22
    • Extracellular Score: 0.97
    • Internal Helices: 2
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.125
    • Ymax_pos: 47
    • Cmax: 0.115
    • Cmax_pos: 53
    • Smax: 0.212
    • Smax_pos: 35
    • Smean: 0.124
    • D: 0.124
  • predicted transmembrane helices (TMHMM): 6

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MPNPIGNMVIKVDLDGSGFNRGVTGLNRQMKMVSRELSANLSQFSRYDNSLEKSKIKVEGLSKKQKVQAQITKELKDSYDKLSKETGENSAKTQAAAAKYNEAYAKLNQYERELNQATQELKDMQREQKALNTAMGKLGTNFNNFGPKLQEIGNSMKNVGRNMTMYVTAPVVAGFAVAAKKGIEFDDSMRKVKATSGATGEEFEALKKKAREMGATTKFSASDSAEALNYMALAGWDSKQMMEGLSGVMDLAAASGEELEAVSDIVTDGLTAFGLKAKDSGHFADILAQTSSKANTDVRGLGEAFKYVAPVAGALGYTIEDTSIAIGLMSNAGIKGEKAGTALRTMFTNLSSPTRAMGNEMERLGISITDSNGKMIPMRKLLDQLREKFKHLSKDQQASSAATIFGKEAMSGALAIINASDEDYQKLTKSIDSSTGASKRMADTMESGLGGKLRTLRSQLEELALTIYDRIEPALKIIVSAFSKVVTWVTKLPTSIQLAVVGFGLFAAVLGPLVFMFGLFISVMGNAMTVLGPLLINVNKAGGLFAFLRTKIASLVKLFPILGVSISSLTLPITLIVGALVGIGIAFYQAYKRSETFRNIVNQAISGVANAFKAAKLALQGFFDLFKGDSKGAVTLEKIFPPETVAGIQNVVNTIRTTFFKVVDAIVGFAKEIGAQLASFWKENGSEITQALQNIAGFIKATFEFIFNFIIKPIMFAIWQVMQFIWPAVKALIVSTWENIKGVIQGAINIILGIIKVFSSLFTGNWRGVWDGIVMILKGTVQLIWNLIQLWFVGKILGVVRYFGGLLKGLISGIWGVIKGIFTKSLSAIWNATKSIFGFLYNSVKSIFTNMKNWLSSTWNNIKSNTVGKAHSLFTGVRSKFTSLWNATKDIFTKLRNWMSNIWNSIKDNTVGIAGRLWDKVRNIFGNMRDGLKSIIGKIKDHIGGMVDAIKKGLNKLIEGLNWVGGKLGMDEIPRLHTGTEHTHTTTRLVKNGKIARDTFATVGDKGRGNGPNGFRNEMIEFPNGKRVITPSTDTTAYLPKGSKVYNGAQTYSMLNGTLPRFHFGTTMWKDIKSSASSAFNWTKDQIGKGTKWLGDKVGDVMDFIDNPGKLLNYVLQAFGVDFSSLTKGMGIAGDITKAAWSKIKKSAIKWLEDAFAESGDGGVLDMSKLRYLYGHTAAYTRETGRPFHEGLDFDYIYEPVPSTINGRAQVMPVHNGGYGKWVKIVKGALEVIYAHLSKYKVKTGQQVRVGQTVGISGNTGFSTGPHLHYEMRWNGRHRDPLPWLRKNNGGGKSTPGGNGAANARRAIKAAQNILGGRYKASWITNEMMRVASRESNYTANAVNNWDSNARAGIPSRGMFQMIDPSFRAYAKSGYNNPLNPTHQAISAMRYIVGKWVPRTGSWRAAFKRAGDYAYATGGKVYNGLYHLGEEGYPEWIIPTDPSRANEAHKLLALAANDIDNRSKNKRPNNLPNPSISNSDTNYIHTLENKLDAVINCLVSLVESNQVIADKDYEPVINKYVFEDEVNNSIDKRERHESTRVRFRRGGTII

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet.: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit source | edit]