From AureoWiki
Jump to: navigation, search
Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40

NCBI: 03-AUG-2016

Summary[edit source | edit]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_03042
  • pan locus tag?: SAUPAN006469000
  • symbol: SAOUHSC_03042
  • pan gene symbol?:
  • synonym:
  • product: integrase/recombinase core subunit

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAOUHSC_03042
  • symbol: SAOUHSC_03042
  • product: integrase/recombinase core subunit
  • replicon: chromosome
  • strand: +
  • coordinates: 2812084..2812434
  • length: 351
  • essential: no DEG

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    TTGCACCTTTTCATTTTATCTTCTCATATATTTAAATCAATTACTTTTGATTGTGGTAAG
    GAGTTCTCAAACTGGAAAACAATATGTAACTGTCACGATATATCTATATTTTTTGCTGAT
    CCAGGCACGCCATCACAGCGAGGTTTAAATGAACATTCTAACGGAATAATTAGACGCAGT
    GGATTAGATAAAGAACTAGATTTCAATTTAGTAACGGATGATCATATCATCAGTGTTGCT
    CAAAAAATCAATCATCATCCTAGAAAATCTTTAGGTTATAGAACACCATTGGAAGTATTT
    ATGAGTTTCATCGAAGATGATAAACTTGTCCAGCTTAATTTGACAATCTAA
    60
    120
    180
    240
    300
    351

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAOUHSC_03042
  • symbol: SAOUHSC_03042
  • description: integrase/recombinase core subunit
  • length: 116
  • theoretical pI: 6.87644
  • theoretical MW: 13316.1
  • GRAVY: -0.198276

Function[edit source | edit]

  • TIGRFAM:
  • TheSEED:  
    Integrase/recombinase, core domain family 
  • PFAM:
    RNase_H (CL0219) rve; Integrase core domain (PF00665; HMM-score: 26.2)
    rve_3; Integrase core domain (PF13683; HMM-score: 26.1)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.182
    • Ymax_pos: 20
    • Cmax: 0.141
    • Cmax_pos: 40
    • Smax: 0.363
    • Smax_pos: 1
    • Smean: 0.276
    • D: 0.219
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MHLFILSSHIFKSITFDCGKEFSNWKTICNCHDISIFFADPGTPSQRGLNEHSNGIIRRSGLDKELDFNLVTDDHIISVAQKINHHPRKSLGYRTPLEVFMSFIEDDKLVQLNLTI

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SAOUHSC_03042 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet.: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit source | edit]