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Summary[edit source | edit]

  • pan ID?: SAUPAN003858000
  • symbol?: dfrA
  • description?: dihydrofolate reductase

      descriptions from strain specific annotations:

    • dihydrofolate reductase
    • dihydrofolate reductase type 1 from Tn4003
    • dihydrofolate reductase type I
    • trimethoprim-sensitive dihydrofolate reductase
  • strand?: -
  • coordinates?: 4139681..4140160
  • synteny block?: BlockID0029140
  • occurrence?: in 100% of 32 strains

Orthologs[edit source | edit]

    COL:
    SACOL1461 (folA)
    N315:
    SA1259 (dfrA)
    NCTC8325:
    Newman:
    NWMN_1337 (dfrA)
    USA300_FPR3757:
    04-02981:
    SA2981_1380 (dfrA)
    08BA02176:
    C248_1466 (dfrB)
    11819-97:
    MS7_1382 (folA)
    71193:
    ST398NM01_1427
    ECT-R 2:
    ECTR2_1282
    ED133:
    SAOV_1435c
    ED98:
    SAAV_1409 (folA)
    HO 5096 0412:
    SAEMRSA15_12890 (dfrB)
    JH1:
    SaurJH1_1515
    JH9:
    SaurJH9_1486
    JKD6008:
    SAA6008_01394 (dfrA)
    JKD6159:
    SAA6159_01293 (dfrA)
    LGA251:
    SARLGA251_13420 (dfrB)
    M013:
    M013TW_1372
    MRSA252:
    SAR1439 (dfrB)
    MSHR1132:
    SAMSHR1132_12680
    MSSA476:
    SAS1369
    Mu3:
    SAHV_1414 (dfrA)
    Mu50:
    SAV1426 (dfrA)
    MW2:
    MW1316 (dfrA)
    RF122:
    SAB1281c (dfrB)
    ST398:
    SAPIG1427 (folA)
    T0131:
    SAT0131_01506 (guaB)
    TCH60:
    HMPREF0772_11780 (folA)
    TW20:
    SATW20_14270 (dfrB)
    USA300_TCH1516:
    USA300HOU_1363 (dfrB)
    VC40:
    SAVC_06380

Genome Viewer[edit source | edit]

COL chromosome
N315 chromosome
NCTC8325 chromosome
Newman chromosome
USA300_FPR3757 chromosome

Alignments[edit source | edit]

  • alignment of orthologues:
    CLUSTAL format alignment by MAFFT L-INS-i (v7.205)


    COL             MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRN
    N315            MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRN
    NCTC8325        MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRN
    Newman          MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRN
    USA300_FPR3757  MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRN
                    ************************************************************

    COL             VVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRG
    N315            VVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRG
    NCTC8325        VVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRG
    Newman          VVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRG
    USA300_FPR3757  VVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRG
                    ************************************************************

    COL             DTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK
    N315            DTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK
    NCTC8325        DTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK
    Newman          DTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK
    USA300_FPR3757  DTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK
                    ***************************************