NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS12620
• pan locus tag^?:
• symbol: SA_RS12620
• pan gene symbol^?: —
• synonym:
• product: amino acid ABC transporter permease

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS12620
• symbol: SA_RS12620
• product: amino acid ABC transporter permease
• replicon: chromosome
• strand: -
• coordinates: 2470101..2470820
• length: 720
• essential: unknown

⊟Accession numbers

• Location: NC_002745 (2470101..2470820) NCBI
• MicrobesOnline:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  
  ATGTTTCTAAATCTAAATAGCGAACAACAACATGCGCTAGATGCTGCAAAACAAGCTTTC
  GGACCTATGCTAGAAGGTTTGGTCAAATATTCAATTCCTATTACATTAGTTACATTTGTT
  TTAGGATTGATTATTGCATTATTTACAGCATTAATGCGAATTTCAACGAGTAAAATTTTA
  AGAAGTATTTCACGTGTCTATGTATCTATTATTCGAGGAACACCAATGATAGTACAACTA
  TTTATCATATTTTATGGTATTCCAGAATTAGGTAGATTATTAACAAATGACGCTGACAAC
  CAATGGACATTGGCACCTGTAGTGGCTGCTATTATTGGTTTATCATTAAATGTAGGTGCG
  TATGCTTCGGAAATTATTCGTGGCGGTATTATTTCTATACCGAAAGGACAAACAGAAGCT
  GCATATTCCATCGGTATGACGTATGGTCAAACGATACAACGTATCATTTTACCGCAGGCA
  ATTCGAGTGTCGATTCCTGCACTAGGTAATACATTTTTAAGTTTAATCAAAGATACATCA
  TTATTAGGATTTATTTTAGTGGCTGAAATGTTTAGAAAAGCTCAAGAAGTTGCGTCTACA
  ACATATGAATATTTAACAATTTATGTGTTAGTTGCGCTAATGTACTGGGTGGTATGCTTT
  ATTATTTCAATTATCCAAGGTATCTATGAATCTTATATTGAAAGAGGGTATCGCTCATGA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  

⊟Protein

⊟General

• locus tag: SA_RS12620
• symbol: SA_RS12620
• description: amino acid ABC transporter permease
• length: 239
• theoretical pI: 9.13859
• theoretical MW: 26442.2
• GRAVY: 0.682427

⊟Function

• TIGRFAM:
  ectoine/hydroxyectoine ABC transporter, permease protein EhuC (TIGR03004; HMM-score: 159.4)
  ectoine/hydroxyectoine ABC transporter, permease protein EhuD (TIGR03003; HMM-score: 138.3)
  and 7 more
  MetabolismTransport and binding proteinsAmino acids, peptides and aminesamino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family (TIGR01726; HMM-score: 84)
  MetabolismTransport and binding proteinsAnionsphosphate ABC transporter, permease protein PstA (TIGR00974; HMM-score: 23.7)
  MetabolismTransport and binding proteinsAnionsphosphate ABC transporter, permease protein PstC (TIGR02138; HMM-score: 20.9)
  MetabolismTransport and binding proteinsAnionsphosphonate ABC transporter, permease protein PhnE (TIGR01097; HMM-score: 17.5)
  Cellular processesCellular processesChemotaxis and motilityflagellar biosynthetic protein FliQ (TIGR01402; HMM-score: 15.1)
  Cellular processesCellular processesPathogenesistype III secretion protein, HrpO family (TIGR01403; HMM-score: 4.8)
  Genetic information processingProtein fateProtein and peptide secretion and traffickingtype III secretion protein, HrpO family (TIGR01403; HMM-score: 4.8)
• TheSEED:
• PFAM:
  BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 86.7)
  and 5 more
  no clan definedBac_export_3; Bacterial export proteins, family 3 (PF01313; HMM-score: 15.7)
  DUF3377; Domain of unknown function (DUF3377) (PF11857; HMM-score: 12.6)
  WSS_VP; White spot syndrome virus structural envelope protein VP (PF12175; HMM-score: 11.9)
  Tetraspannin (CL0347) DUF4064; Protein of unknown function (DUF4064) (PF13273; HMM-score: 10)
  Oxa1 (CL0376) DUF106; Integral membrane protein DUF106 (PF01956; HMM-score: 9.5)

⊟Structure, modifications & interactions

• domains:
• modifications:
• cofactors:
• effectors:
• protein partners:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 4
• LocateP:
• SignalP: no predicted signal peptide
  • Ymax: 0.118
  • Ymax_pos: 19
  • Cmax: 0.109
  • Cmax_pos: 19
  • Smax: 0.168
  • Smax_pos: 15
  • Smean: 0.114
  • D: 0.117
• predicted transmembrane helices (TMHMM): 4

⊟Accession numbers

• GI: 446401721 NCBI
• RefSeq: WP_000479576 NCBI
• UniProt:

⊟Protein sequence

• MFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKILRSISRVYVSIIRGTPMIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIILPQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS

⊟Experimental data

• experimentally validated: no data available

⊟Expression & Regulation

⊟Operon

• SA_RS12620 no polycistronic organisation predicted

⊟Regulation

• sigma factor:
• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Other Information

You are kindly invited to share additional interesting facts.