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NCBI: 01-DEC-2025
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: EGJ38_000391 [new locus tag: EGJ38_RS01950 ]
- pan locus tag?: SAUPAN002173000
- symbol: EGJ38_000391
- pan gene symbol?: —
- synonym:
- alternate name: JSNZ_000391
- product: sodium-dependent transporter
⊟Additional information (user-provided)[edit | edit source]
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: EGJ38_000391 [new locus tag: EGJ38_RS01950 ]
- symbol: EGJ38_000391
- product: sodium-dependent transporter
- replicon: chromosome
- strand: +
- coordinates: 419953..421290
- length: 1338
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq: MGT2422392 NCBI
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
⊟Additional information (user-provided)[edit | edit source]
⊟DNA sequence[edit | edit source]
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1321ATGAAAAGACAACAATCACAATGGAAGTCATCAACTGGATTTATTTTAGCTAGTGCGGGT
TCTGCAATCGGTCTTGGTGCCATGTGGAAATTCCCATATATGGCAGGGATTTATGGCGGC
GGTGCCTTTCTAGCTATGTTCTTAATATTCACCATTTTTGTTGGGTTACCATTACTCATT
ATGGAATTCACTGTTGGGAAAATGGGACGGACATATACAACACAAATATATAGTAAATTA
ACTGGTAAAAAATTGCTCAATATCATTGGCTGGAACGGTAATTTGGCCGTGTTTATTTTA
TTTGGCTTCTATAGTGTTATCGGTGGTTGGATTGTCATTTACATCGGACAAGTATTATGG
CAATTAGTTATATTTCAACGCATCAATCATCTCCAAGAAATGAATTTTGAAGCGGTAATA
TCAAATCCTTGGTTAACTGTTCTAGGGCAAGGTATATTCATATTCGCTACGATGATTATT
GTCATGTTAGGTGTTGAAAAAGGATTAGAAAAGGCATCGAAAGTTATGATGCCATTGCTG
TTTGTCTTTTTAATCATCATTGTGATTAAGTCTTTAACATTAGATGGCGCCTTAGAAGGT
GTGAAATTTATTTTACAACCAAGAGTGTCAGAGATTACTGCTGACGGTATCTTGTTTGCG
CTAGGCCAATCATTCTTTACGTTATCATTAGGAACTACAGGTATGATTACTTATGCGAGT
TATGCCTCTAAAGACATGACGATTAAGTCATCAGCTATTTCTATCGTTGTTATGAATATC
TTTGTATCTGTATTGGCAGGTCTAGCTATATTTCCGGCGTTACATAGTTTTGGCTATGAA
CCACAAGAAGGGCCTGGATTATTATTTAAAGTACTGCCAATGGTCTTTAGTCAAATGCAT
CTAGGCACATTATTCTATTTGGGATTCTTAGTGCTGTTCTTATTTGCGGCTTTAACGTCA
TCTATTTCTTTATTAGAATTAAATGTTTCTAACTTCACGAAGAATGACAATACAAAACGT
AAAAAAGTCGCAGTGATCGGTAGTATTTTAGTATTTATCATTAGTATTCCAGCAACCTTA
TCTTTTGGTATCTTAAAAGATGTAAGATTCGGTGCGGGAACGATTTTTGATAATATGGAT
TTCATCGTTTCGAATGTATTGATGCCATTAGGCGCATTAGGTACTACGCTTGTCGTAGGA
CAATTATTAGATAAAAAATTATTACAACAATATTTTGGTAAAGATCGATTTAGATTATTC
AGTGGTTGGTATTACTTAATTAAGTATGCGATGCCTGTCGTTATTATTTTAGTCTTTATC
GTGCAATTATTTAGTTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: EGJ38_000391 [new locus tag: EGJ38_RS01950 ]
- symbol: EGJ38_000391
- description: sodium-dependent transporter
- length: 445
- theoretical pI: 10.1621
- theoretical MW: 49164.7
- GRAVY: 0.849438
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: APC (CL0062) SNF; Sodium:neurotransmitter symporter family (PF00209; HMM-score: 158.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 11
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0.9996
- Cell wall & surface Score: 0
- Extracellular Score: 0.0004
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.00797
- TAT(Tat/SPI): 0.003434
- LIPO(Sec/SPII): 0.083448
- predicted transmembrane helices (TMHMM): 11
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: MGT2422392 NCBI
- UniProt:
⊟Additional information (user-provided)[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKRQQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFLAMFLIFTIFVGLPLLIMEFTVGKMGRTYTTQIYSKLTGKKLLNIIGWNGNLAVFILFGFYSVIGGWIVIYIGQVLWQLVIFQRINHLQEMNFEAVISNPWLTVLGQGIFIFATMIIVMLGVEKGLEKASKVMMPLLFVFLIIIVIKSLTLDGALEGVKFILQPRVSEITADGILFALGQSFFTLSLGTTGMITYASYASKDMTIKSSAISIVVMNIFVSVLAGLAIFPALHSFGYEPQEGPGLLFKVLPMVFSQMHLGTLFYLGFLVLFLFAALTSSISLLELNVSNFTKNDNTKRKKVAVIGSILVFIISIPATLSFGILKDVRFGAGTIFDNMDFIVSNVLMPLGALGTTLVVGQLLDKKLLQQYFGKDRFRLFSGWYYLIKYAMPVVIILVFIVQLFS
⊟Experimental data[edit | edit source]
- experimentally validated: data available for NCTC8325
- protein localization: data available for COL
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: HisR (repression) regulon
HisR (TF) important in Histidine biosynthesis; regulation predicted or transferred from N315 and NCTC 8325 [1]
⊟Additional information (user-provided)[edit | edit source]
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Additional information (user-provided)[edit | edit source]
⊟Other information (user-provided)[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
Curr Res Microb Sci: 2025, 9;100489
[PubMed:41146725] [WorldCat.org] [DOI] (I e)