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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000353
  • pan locus tag?: SAUPAN002102000
  • symbol: JSNZ_000353
  • pan gene symbol?: —
  • synonym:
  • product: SDR family oxidoreductase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000353
  • symbol: JSNZ_000353
  • product: SDR family oxidoreductase
  • replicon: chromosome
  • strand: -
  • coordinates: 386014..386859
  • length: 846
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAATATTATGTTAACAGGTGCTACAGGTCATTTAGGCACACATATTACAAATCAAGCC
    ATTGCAAATCACATAGATCATTTTCACATTGGTGTTAGAAATGTTGAGAAAGTTCCAGAA
    GATTGGCGTGGAAAAGTTTCTGTTCGACAATTAGATTATTTTAATCCCGAAAGTATGGTA
    GAAGCATTTAAAGGAATGGATACCATTGTATTTATTCCTAGTATTATTCACCCATCATTC
    AAACGTATTCCTGAAGTGGAAAATTTAGTATATGCGGCAAAGCAAAGTGGCGTTGCACAT
    ATCATTTTCATAGGTTATTACGCAGATCAGCATAATAATCCATTCCATATGAGTCCTTAT
    TTTGGTTATGCAGCACGTCTATTGGCAACAAGTGGCATTGACTATACCTATGTAAGAATG
    GCAATGTACATGGATCCACTTAAACCATATTTACCAGAATTGATGAATATGCATAAACTG
    ATTTATCCAGCTGGTGATGGTCGTATTAATTATATTACTAGAAATGATATTGCTAGAGGT
    GTCATTGCTATTATTAAAAATCCAGATACTTGGGGCAAACGCTATTTATTATCAGGCTAC
    AGTTATGATATGAAAGAACTTGCTGCAATTTTATCTGAGGCATCAGGCACAGAAATTAAA
    TATGAACCCGTTTCATTAGAGACATTTGCAGAAATGTACGATGAACCTAAAGGCTTTGGT
    GCATTATTGGCATCAATGTACGACGCAGGAGCAAGAGGACTATTAGACCAAGAATCCAAT
    GATTTCCAACAATTAGTCAATGATCAACCACAGACACTGCAATCATTTTTACAAGAAAAT
    ATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    846

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000353
  • symbol: JSNZ_000353
  • description: SDR family oxidoreductase
  • length: 281
  • theoretical pI: 5.7659
  • theoretical MW: 31800.1
  • GRAVY: -0.209253

⊟Function[edit | edit source]

  • reaction:
    EC 1.6.5.2?  ExPASy
    NAD(P)H dehydrogenase (quinone) NAD(P)H + a quinone = NAD(P)+ + a hydroquinone
  • TIGRFAM:
    ergot alkaloid biosynthesis protein, AFUA_2G17970 family (TIGR03649; HMM-score: 49)
    and 4 more
    Hypothetical proteins Conserved TIGR01777 family protein (TIGR01777; HMM-score: 16.9)
    hopanoid-associated sugar epimerase (TIGR03466; HMM-score: 16.5)
    thioester reductase domain (TIGR01746; HMM-score: 14.5)
    NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family (TIGR04180; HMM-score: 13)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    NADP_Rossmann (CL0063) NAD_binding_10; NAD(P)H-binding (PF13460; HMM-score: 83.7)
    NmrA; NmrA-like family (PF05368; HMM-score: 71.9)
    and 5 more
    Epimerase; NAD dependent epimerase/dehydratase family (PF01370; HMM-score: 24.9)
    RmlD_sub_bind; RmlD substrate binding domain (PF04321; HMM-score: 14.9)
    3Beta_HSD; 3-beta hydroxysteroid dehydrogenase/isomerase family (PF01073; HMM-score: 12.8)
    no clan defined NifT; NifT/FixU protein (PF06988; HMM-score: 11.9)
    NADP_Rossmann (CL0063) NAD_binding_4; Male sterility protein (PF07993; HMM-score: 11.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9971
    • Cytoplasmic Membrane Score: 0.0006
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0022
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.029736
    • TAT(Tat/SPI): 0.000737
    • LIPO(Sec/SPII): 0.002296
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNIMLTGATGHLGTHITNQAIANHIDHFHIGVRNVEKVPEDWRGKVSVRQLDYFNPESMVEAFKGMDTIVFIPSIIHPSFKRIPEVENLVYAAKQSGVAHIIFIGYYADQHNNPFHMSPYFGYAARLLATSGIDYTYVRMAMYMDPLKPYLPELMNMHKLIYPAGDGRINYITRNDIARGVIAIIKNPDTWGKRYLLSGYSYDMKELAAILSEASGTEIKYEPVSLETFAEMYDEPKGFGALLASMYDAGARGLLDQESNDFQQLVNDQPQTLQSFLQENI

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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