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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000384
  • pan locus tag?: SAUPAN002163000
  • symbol: JSNZ_000384
  • pan gene symbol?: mpsA
  • synonym:
  • product: NADH dehydrogenase subunit 5

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000384
  • symbol: JSNZ_000384
  • product: NADH dehydrogenase subunit 5
  • replicon: chromosome
  • strand: +
  • coordinates: 412643..414127
  • length: 1485
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    GTGTTAAGTTTTCAATTGCTATTTTCACTGTTTGTTATTGCGCTTATCATTGCATTGATA
    AGTGGCTTGTTGTTTTTAGCACCAGTTATGCCAATGAGATATATTAAATTACATTTATAC
    ATACTAGTCATGCCAGTATTATTTGCAGTCATTGGCTTTTTCGGTATTCATGGTCAACAT
    GTCTTAGGTCCATTTAAAATAGATCGTTTATCTTGGTTATTAGCTGGCTTTGTAATGGCG
    CTTGGATTTATTATTCAAAAGTTTTCAATGAGATATTTACTAGGTGATCATCATTATAGA
    CATTACTTTCCATTGTTCACTGCGATTACGTCGTTTGCATCTTTAGCATGGATGTCTGAA
    GACTTAAGACTGATGGCACTCTGCTGGGGTATGACATTATTATGTTTAACACTGCTGATG
    AACGTTAATCGTTTTTGGAAAGTGCCACGTGAGTCTGCGAAATTATCAAGCATGACATTT
    TTATGTGGTTGGCTTGCATTCGTTGGAGCAATTGTAACTATTTATATTGCGACTGGCGAG
    TGGCGCGTGCCTCAACATATGTCTAATTCGACATGGTCATTGTTGACGAATGTACTACTT
    GTATTAGCTGTCATGATACCAGCAGCACAATTTCCATTTCATCGATGGTTGATTGAATCT
    GTAACAGCACCAACGCCAGTATCGGCAATTATGCATGCAGGAATTGTGAATGCAGGTGGT
    GTTATTCTAACTCGTTTTGCGCCGATATTTGATAATGGATTTGCGTTATCATTATTACTT
    ATCCTTTCTAGTATTTCTGTATTGTTAGGATCGGGTATTAGCTTGGTTCAAGTGGATTAC
    AAAAGACAGTTAGTCGGCTCTACGATGAGTCAAATGGGCTTTATGTTAGTTCAATGTGCA
    TTGGGTGTATATTCAGCAGCGATTATTCATTTAATATTGCACGGTATTTTTAAAGCAACA
    TTATTTTTACAATCAGGTTCTATCGTGAAGCGATTCAATATTCCAAAACAAGCATCTGCT
    AAAGACGCTTATGGCTGGATTGTCATGGGACGTGTATTAGCTATTATCGTGGCATTTCTA
    TTTTGGATGAGTAGTGACAGAAGTGCATATGAAGTGTTAAGTGCACTCATTCTAGCATGG
    TCATTACTTGTATCTTGGAATCAGATGGTAGCCTTTAGTAAAGGGCGCATGGCACGTCTG
    GTTGGCATGATTTTGATTGCAATTGTGACATTTATCTACATCATCACACATAATTATTTT
    TACGATGTATTGCGAAATATAACAACACATGCGACAACACCGCCTACAGTGAGTGTCATC
    ATTAGTGTTGTCATTTTAATCTTTGGTAGTTTATTAAGTATTTGGGTAGCGCGTCATCGA
    TACTCTAAGACTTTTGCGGTATTGTACGTGTGGTTAGTTAATTTAGGTGAAGCACGCTCG
    AAAGCGATAGAAAGTCATCCGAATTATTTGAAGAAGTATTTATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1485

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000384
  • symbol: JSNZ_000384
  • description: NADH dehydrogenase subunit 5
  • length: 494
  • theoretical pI: 10.3577
  • theoretical MW: 55377.2
  • GRAVY: 0.88502

⊟Function[edit | edit source]

  • reaction:
    EC 1.6.5.9?  ExPASy
    NADH:ubiquinone reductase (non-electrogenic) NADH + ubiquinone = NAD+ + ubiquinol
  • TIGRFAM:
    Metabolism Energy metabolism Electron transport proton-translocating NADH-quinone oxidoreductase, chain L (TIGR01974; EC 1.6.-.-; HMM-score: 136.2)
    and 4 more
    Metabolism Transport and binding proteins Cations and iron carrying compounds monovalent cation:proton antiporter (TIGR00940; HMM-score: 90.7)
    NAD(P)H dehydrogenase, subunit NdhF3 family (TIGR01960; HMM-score: 59.4)
    Metabolism Energy metabolism Electron transport proton-translocating NADH-quinone oxidoreductase, chain M (TIGR01972; HMM-score: 57.6)
    Metabolism Energy metabolism Electron transport proton-translocating NADH-quinone oxidoreductase, chain N (TIGR01770; HMM-score: 24.6)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    ComplexI-N (CL0425) Proton_antipo_M; NADH:quinone oxidoreductase/Mrp antiporter, TM (PF00361; HMM-score: 172.2)
    and 2 more
    no clan defined Proton_antipo_N; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus (PF00662; HMM-score: 24.3)
    FixQ; Cbb3-type cytochrome oxidase component FixQ (PF05545; HMM-score: 14.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 14
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0002
    • Cytoplasmic Membrane Score: 0.9991
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0007
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004434
    • TAT(Tat/SPI): 0.00094
    • LIPO(Sec/SPII): 0.018181
  • predicted transmembrane helices (TMHMM): 14

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MLSFQLLFSLFVIALIIALISGLLFLAPVMPMRYIKLHLYILVMPVLFAVIGFFGIHGQHVLGPFKIDRLSWLLAGFVMALGFIIQKFSMRYLLGDHHYRHYFPLFTAITSFASLAWMSEDLRLMALCWGMTLLCLTLLMNVNRFWKVPRESAKLSSMTFLCGWLAFVGAIVTIYIATGEWRVPQHMSNSTWSLLTNVLLVLAVMIPAAQFPFHRWLIESVTAPTPVSAIMHAGIVNAGGVILTRFAPIFDNGFALSLLLILSSISVLLGSGISLVQVDYKRQLVGSTMSQMGFMLVQCALGVYSAAIIHLILHGIFKATLFLQSGSIVKRFNIPKQASAKDAYGWIVMGRVLAIIVAFLFWMSSDRSAYEVLSALILAWSLLVSWNQMVAFSKGRMARLVGMILIAIVTFIYIITHNYFYDVLRNITTHATTPPTVSVIISVVILIFGSLLSIWVARHRYSKTFAVLYVWLVNLGEARSKAIESHPNYLKKYL

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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