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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000400
  • pan locus tag?: SAUPAN002182000
  • symbol: JSNZ_000400
  • pan gene symbol?: —
  • synonym:
  • product: GNAT family N-acetyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000400
  • symbol: JSNZ_000400
  • product: GNAT family N-acetyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 428735..429220
  • length: 486
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGACAAATAATGACACCATCATGTTACGACATTATGTCCCACAAGATTATTCGATGTTA
    GAAGCTTTTCAATTAAGTGAAAGTGATTTGAAGTTTGTTAAAACGCCAGAGGAAAATATT
    ACAGCTGCAATGTCTGATAATGAAAGGTATCCCATCGTTGTAATGGATGGCAAGCAATGT
    GTGGCCTTTTTTACATTACATCGTGGAAAAGGGGTCGCACCATTTAGCGATAACCAAGAT
    GCAGTATTTTTCAGGTCATTTAGTGTTGATCAACGTTATCGTAATAGAGGAATAGGTAAA
    GTGGTAATGGAAAAATTGGCGTCATTTATCACTTCAACATTTCAGGATGTTAATGAGATT
    GTGTTAACGGTTAATACTGACAATCCACATGCCATGGCACTTTATCGCCAACAAGGATAT
    CAATATATGGGAGATAGTATGTTCGTCGGAAGACCTGTTCATATTATGGCGTTAACTATA
    AAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    486

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000400
  • symbol: JSNZ_000400
  • description: GNAT family N-acetyltransferase
  • length: 161
  • theoretical pI: 6.51477
  • theoretical MW: 18438
  • GRAVY: -0.248447

⊟Function[edit | edit source]

  • reaction:
    EC 2.3.1.-?  ExPASy
  • TIGRFAM:
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 37.7)
    and 4 more
    UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (TIGR03585; EC 2.3.1.202; HMM-score: 25.2)
    GNAT-family acetyltransferase TIGR03103 (TIGR03103; HMM-score: 18.2)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs mycothiol synthase (TIGR03448; EC 2.3.1.189; HMM-score: 13.8)
    Cellular processes Cellular processes Adaptations to atypical conditions diaminobutyrate acetyltransferase (TIGR02406; EC 2.3.1.178; HMM-score: 12.9)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 45.3)
    and 8 more
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 32.1)
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 31.8)
    FR47; FR47-like protein (PF08445; HMM-score: 21.2)
    Acetyltransf_15; Putative acetyl-transferase (PF17013; HMM-score: 20.2)
    Acetyltransf_8; Acetyltransferase (GNAT) domain (PF13523; HMM-score: 16.4)
    Acetyltransf_CG; GCN5-related N-acetyl-transferase (PF14542; HMM-score: 15.8)
    Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 15)
    Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 14.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9522
    • Cytoplasmic Membrane Score: 0.001
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0468
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004149
    • TAT(Tat/SPI): 0.000193
    • LIPO(Sec/SPII): 0.000477
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTNNDTIMLRHYVPQDYSMLEAFQLSESDLKFVKTPEENITAAMSDNERYPIVVMDGKQCVAFFTLHRGKGVAPFSDNQDAVFFRSFSVDQRYRNRGIGKVVMEKLASFITSTFQDVNEIVLTVNTDNPHAMALYRQQGYQYMGDSMFVGRPVHIMALTIK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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