PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

FunGene: 08-OCT-2024

⊟Summary

• organism: Staphylococcus aureus JSNZ
• locus tag: JSNZ_000655
• pan locus tag^?: SAUPAN002571000
• symbol: JSNZ_000655
• pan gene symbol^?: —
• synonym:
• product: GTP-binding protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: JSNZ_000655
• symbol: JSNZ_000655
• product: GTP-binding protein
• replicon: chromosome
• strand: +
• coordinates: 688621..689547
• length: 927
• essential: unknown other strains

⊟Accession numbers

• Gene ID:
• RefSeq:
• BioCyc:
• MicrobesOnline:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  
  ATGAAAAATAATAAAGATGAAAAAATAAGAATATCCATAATTAACGGATTTTTGGGTAGT
  GGTAAAACCACGTTACTGACACATTATATTAGTGAATTATTAAAAAATGATGAGAAAATT
  AAAATCATCATGAATGAATTCGGTACTTTTGATATTGATAGCAATAGTATTTCAAATGAA
  ATTGAAGTCCATTCATTGATTAATGGTTGTGTTTGTTGCGATCTTAAACAAGAACTTGTC
  TATGAACTAAAAGCCATTGCTTTAAAAGGGGACGTTAATCATGTCATCATAGAAGCGACA
  GGCATTGCGCATCCTTTAGAATTACTAGTTGCATGTCAAGATCCGCAAATCGTTAATTTC
  TTTGAAAAGCCGATTATTTATGGTGTATTAGATGCGACTCGATTTTTGGAACGTCATCAA
  TATACCGAAAATACAGTTTCGCTGATGGAAGATCAGTTGAAACTAAGTGACATGATTATT
  ATTAATAAAATTGATCTTGTAACTGATGACAGTCTTGAGAAAATTGATAAGCAATTAAGT
  ATGATTTGTGCAAGTATTCCAACTTATAAAACAACCTATGGAAAAGTTTTGTTGGAAGAA
  TTGGACTTAACTGTTAAAGACAGAGAGATATCGTCTCATCATCACCATCATCATGGGATT
  AAAAGTATGACTTACACGTTTACAGGTCCGATTGATCGTCAATTGTTTTATCAATTTATA
  ATGAAATTACCGGAATCTGTTCTACGTTTGAAAGGTTATGTGTCATTTAGAGATCAACCA
  AATGCAATTTATGAATTTCAATATGCATATGGTTTACCAGACTATGGAATAATTGGCATG
  CAATTACCATTAACGATTGTTATTATTGGTGAAACTTTAGATACAAATCACATACGTAAT
  CAATTGGATATGCTACAATTTACGTAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  927
  

⊟Protein

⊟General

• locus tag: JSNZ_000655
• symbol: JSNZ_000655
• description: GTP-binding protein
• length: 308
• theoretical pI: 5.3599
• theoretical MW: 35257.5
• GRAVY: -0.0801948

⊟Function

• TIGRFAM:
  Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin cobalamin biosynthesis protein CobW (TIGR02475; HMM-score: 101.8)
  and 3 more
  Genetic information processing Protein fate Protein modification and repair hydrogenase accessory protein HypB (TIGR00073; HMM-score: 22.7)
  Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Molybdopterin molybdopterin-guanine dinucleotide biosynthesis protein B (TIGR00176; HMM-score: 15.7)
  KaiC domain protein, AF_0351 family (TIGR03880; HMM-score: 13.9)
• TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
• PFAM:
  P-loop_NTPase (CL0023) cobW; CobW/HypB/UreG, nucleotide-binding domain (PF02492; HMM-score: 168.2)
  and 14 more
  CobW_C (CL0832) CobW_C; Cobalamin synthesis protein cobW C-terminal domain (PF07683; HMM-score: 53.8)
  P-loop_NTPase (CL0023) MobB; Molybdopterin guanine dinucleotide synthesis protein B (PF03205; HMM-score: 22.8)
  AAA_22; AAA domain (PF13401; HMM-score: 18.8)
  GTP_EFTU; Elongation factor Tu GTP binding domain (PF00009; HMM-score: 18.1)
  AAA_14; AAA domain (PF13173; HMM-score: 17.2)
  RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 15.4)
  no clan defined MMR_HSR1_Xtn; C-terminal region of MMR_HSR1 domain (PF16897; HMM-score: 15.3)
  P-loop_NTPase (CL0023) NPHP3_N; Nephrocystin 3, N-terminal (PF24883; HMM-score: 15)
  no clan defined DUF2824; Protein of unknown function (DUF2824) (PF11039; HMM-score: 14.7)
  P-loop_NTPase (CL0023) ATPase_2; ATPase domain predominantly from Archaea (PF01637; HMM-score: 13.9)
  Arf; ADP-ribosylation factor family (PF00025; HMM-score: 13)
  AAA_19; AAA domain (PF13245; HMM-score: 12.5)
  T2SSE; Type II/IV secretion system protein (PF00437; HMM-score: 12.4)
  NB-ARC; NB-ARC domain (PF00931; HMM-score: 11.5)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9744
  • Cytoplasmic Membrane Score: 0.0249
  • Cell wall & surface Score: 0.0001
  • Extracellular Score: 0.0006
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.009718
  • TAT(Tat/SPI): 0.000283
  • LIPO(Sec/SPII): 0.001616
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq:
• UniProt:

⊟Protein sequence

• MKNNKDEKIRISIINGFLGSGKTTLLTHYISELLKNDEKIKIIMNEFGTFDIDSNSISNEIEVHSLINGCVCCDLKQELVYELKAIALKGDVNHVIIEATGIAHPLELLVACQDPQIVNFFEKPIIYGVLDATRFLERHQYTENTVSLMEDQLKLSDMIIINKIDLVTDDSLEKIDKQLSMICASIPTYKTTYGKVLLEELDLTVKDREISSHHHHHHGIKSMTYTFTGPIDRQLFYQFIMKLPESVLRLKGYVSFRDQPNAIYEFQYAYGLPDYGIIGMQLPLTIVIIGETLDTNHIRNQLDMLQFT

⊟Experimental data

• experimentally validated: data available for NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications