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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001468
  • pan locus tag?: SAUPAN003947000
  • symbol: JSNZ_001468
  • pan gene symbol?: recQ2
  • synonym:
  • product: ATP-dependent DNA helicase RecQ

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001468
  • symbol: JSNZ_001468
  • product: ATP-dependent DNA helicase RecQ
  • replicon: chromosome
  • strand: -
  • coordinates: 1513349..1514728
  • length: 1380
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGTTGCATGATATTTTACGAAACAAATTTGGCTTCGAGAATTTTAAACCGGGACAACAG
    GAAATTATAGAAAGTATAATGTCTCAACAACACACTCTAGGTATTCTTCCAACTGGAAGT
    GGAAAGAGTTTGTGTTATCAAATACCTACGTATTTATCAGGTAAGCCGACATTAATTATC
    TCACCGTTAATATCTTTAATGGATGACCAAGTTATGCAGTTGAAAATAAATGGAGAAAAA
    CGTGTAACATGTATTCACTCTGGTATGGATGAAATTGAGAAAAAGCATAATATTAAATGT
    TTACGACATAGCCGCTTCATCTTTCTAAGTCCAGAATTTCTCCTGCAACCGTCAAATTTT
    AAATTAATATCTATGATAGACTTTGGCATGATTGTTTTAGATGAAGCACATTGCCTATCT
    GAATGGGGATATGATTTCAGACCACATTATGCTCTAATAGGAAAAGTAACAAAGCATTTT
    AAAGAAGCGGTTGTCTTAGCATTGACAGCAACTGCACCACCGCATTTACAAGATGATTTG
    ACGGAAATGTTAGCGATTCAATTCAATGTTATTAAAACTACAATGAATCGCCCAAACATA
    AGCTTTAAGCATCTTAATTTTCATGATGATGAAGATAAAATTGAATGGTTGCTGCCGTTT
    CTACAACAGTCGGGACCAACGATTATTTATGTCTCATCGAAAAAGATGTGTCTGAATTTA
    GCGCAACTTATTTATGATTCAGGTTTTCTTACAGGTATTTATCATGGTGATATGAATTAT
    CAAGAGCGACACACAGTTCAACAACAATTTTTAAATAATGATATTCCGATTATAGTCGCA
    ACGAGTGCTTTTGGTATGGGAATTAATAAAAAAGATATTCGCACAATCATTCACTTTCAT
    CTTTCAACAAGTCCTTCTAACTACATTCAAGAAATTGGCCGTGCGGGTCGCGATGGTGAA
    CTAAGTCAGGCAATTAGTTTATTTCAACCGGACGATAAATATATTTTAGAAACGTTATTA
    TTTGCAGATATGATAACAGAAGAAGATGTACAAAATTTCGAAATAGGAGAATTTTTAGCA
    CCCGATAAACAAGACGTTTTGACAACGTTGCGTTCATTCTATAGTATCGGCGCCTTGAAA
    CAGATATTTAAGCAATCATTTAAACGAAAGCAATTAGGATTCTTTCGCATGATTGGCTAT
    TGCAAATTGGATCAATGTAGACGGAAGTATTTATTAGAATTTTTCGGTGAATATCCACCG
    GCACAAGATCGATGTTGTGACAATGATTCTAATATAACTGATATCGCAATTTTAAATAAG
    AAGAAGGTAATTAGAAGTATTGGATTTGATGAAAAGTTGCAAAATTTATTTCTCAGATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001468
  • symbol: JSNZ_001468
  • description: ATP-dependent DNA helicase RecQ
  • length: 459
  • theoretical pI: 7.04877
  • theoretical MW: 52829.8
  • GRAVY: -0.183224

⊟Function[edit | edit source]

  • reaction:
    EC 3.6.4.12?  ExPASy
    DNA helicase ATP + H2O = ADP + phosphate
  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair ATP-dependent DNA helicase RecQ (TIGR01389; EC 3.6.4.12; HMM-score: 346.3)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair ATP-dependent DNA helicase, RecQ family (TIGR00614; EC 3.6.4.12; HMM-score: 339.2)
    and 11 more
    DEXH box helicase, DNA ligase-associated (TIGR04121; EC 3.6.4.-; HMM-score: 44.6)
    helicase/secretion neighborhood putative DEAH-box helicase (TIGR03817; HMM-score: 29.6)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair reverse gyrase (TIGR01054; EC 3.6.4.12,5.99.1.3; HMM-score: 22.5)
    CRISPR-associated helicase Cas3 (TIGR01587; HMM-score: 20.8)
    DNA phosphorothioation system restriction enzyme (TIGR04095; HMM-score: 17.3)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair ATP-dependent DNA helicase RecG (TIGR00643; EC 3.6.4.12; HMM-score: 16.8)
    CRISPR-associated helicase Cas3, subtype CYANO (TIGR03158; HMM-score: 13.7)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair transcription-repair coupling factor (TIGR00580; EC 3.6.1.-; HMM-score: 13.3)
    glutaredoxin-like protein NrdH (TIGR02194; HMM-score: 12.6)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair putative DnaQ family exonuclease/DinG family helicase (TIGR01407; HMM-score: 12.3)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit B (TIGR00631; EC 3.1.25.-; HMM-score: 11.9)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    P-loop_NTPase (CL0023) DEAD; DEAD/DEAH box helicase (PF00270; HMM-score: 94.5)
    Helicase_C; Helicase conserved C-terminal domain (PF00271; HMM-score: 94.5)
    and 2 more
    ResIII; Type III restriction enzyme, res subunit (PF04851; HMM-score: 40.5)
    no clan defined RecQ_Zn_bind; RecQ zinc-binding (PF16124; HMM-score: 35.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9394
    • Cytoplasmic Membrane Score: 0.0332
    • Cell wall & surface Score: 0.001
    • Extracellular Score: 0.0264
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.015277
    • TAT(Tat/SPI): 0.000755
    • LIPO(Sec/SPII): 0.000709
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MLHDILRNKFGFENFKPGQQEIIESIMSQQHTLGILPTGSGKSLCYQIPTYLSGKPTLIISPLISLMDDQVMQLKINGEKRVTCIHSGMDEIEKKHNIKCLRHSRFIFLSPEFLLQPSNFKLISMIDFGMIVLDEAHCLSEWGYDFRPHYALIGKVTKHFKEAVVLALTATAPPHLQDDLTEMLAIQFNVIKTTMNRPNISFKHLNFHDDEDKIEWLLPFLQQSGPTIIYVSSKKMCLNLAQLIYDSGFLTGIYHGDMNYQERHTVQQQFLNNDIPIIVATSAFGMGINKKDIRTIIHFHLSTSPSNYIQEIGRAGRDGELSQAISLFQPDDKYILETLLFADMITEEDVQNFEIGEFLAPDKQDVLTTLRSFYSIGALKQIFKQSFKRKQLGFFRMIGYCKLDQCRRKYLLEFFGEYPPAQDRCCDNDSNITDIAILNKKKVIRSIGFDEKLQNLFLR

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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