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PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

FunGene: 08-OCT-2024

Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002453
  • pan locus tag?: SAUPAN006046000
  • symbol: JSNZ_002453
  • pan gene symbol?:
  • synonym:
  • product: DUF1433 domain-containing protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002453
  • symbol: JSNZ_002453
  • product: DUF1433 domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2453975..2454397
  • length: 423
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGAACAAAAAACATATTTTTATAATTATTGGTGTCATATTATGTATATGTATAGTTGCT
    ACAGTCATTTATTTAAAAGTGAAATATGACGAAAAAGAAAAACAAAAAGCACTTTACTAC
    AAAGAACAACAGGAGCGTATTACACTCTATCTCCAGCATAATACCAAAGAACCCAATACC
    ATCAAATCTGTGCATTTTACAAGTTTAAAGACAGGACCTATGGGCGATGCCGTAATTGAA
    GGTTACATCAATGAAAATAAAGAAGATGATTTTGTTGCATATGGGTCTCCAGAACATAAT
    TATCAATTTGGTGGAAGTTTAATCAAAAGTAAAAATTTAAGCACATTATTAAAACCAGCA
    CATCAAACCAAAACGCCTGATGATATAAAAAAAGAACTAGATTCTAAAAAGAACGACCGC
    TAA
    60
    120
    180
    240
    300
    360
    420
    423

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: JSNZ_002453
  • symbol: JSNZ_002453
  • description: DUF1433 domain-containing protein
  • length: 140
  • theoretical pI: 9.23901
  • theoretical MW: 16118.5
  • GRAVY: -0.606429

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-galactonate transporter (TIGR00893; HMM-score: 14.3)
    Cellular processes Cellular processes Adaptations to atypical conditions phage shock protein B (TIGR02976; HMM-score: 13.3)
    Metabolism Energy metabolism Electron transport cytochrome c oxidase, subunit II (TIGR02866; EC 1.9.3.1; HMM-score: 12.7)
  • TheSEED: data available for COL, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    no clan defined DUF1433; Protein of unknown function (DUF1433) (PF07252; HMM-score: 130.5)
    and 8 more
    Viral_Beta_CD; Viral Beta C/D like family (PF04530; HMM-score: 15.8)
    DUF3377; Domain of unknown function (DUF3377) (PF11857; HMM-score: 15.3)
    DUF1310; Protein of unknown function (DUF1310) (PF07006; HMM-score: 13.3)
    Sigma_reg_N; Sigma factor regulator N-terminal (PF13800; HMM-score: 12.1)
    ABC-2 (CL0181) ABC2_membrane_3; ABC-2 family transporter protein (PF12698; HMM-score: 11.5)
    Peptidase_AD (CL0130) Presenilin; Presenilin (PF01080; HMM-score: 11.4)
    no clan defined PMP1_2; ATPase proteolipid family (PF08114; HMM-score: 10.6)
    DUF6056; Family of unknown function (DUF6056) (PF19528; HMM-score: 10.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.5515
    • Cell wall & surface Score: 0.0014
    • Extracellular Score: 0.447
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.170628
    • TAT(Tat/SPI): 0.002139
    • LIPO(Sec/SPII): 0.071615
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

Protein sequence[edit | edit source]

  • MNKKHIFIIIGVILCICIVATVIYLKVKYDEKEKQKALYYKEQQERITLYLQHNTKEPNTIKSVHFTSLKTGPMGDAVIEGYINENKEDDFVAYGSPEHNYQFGGSLIKSKNLSTLLKPAHQTKTPDDIKKELDSKKNDR

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]