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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2486 [new locus tag: SACOL_RS13025 ]
  • pan locus tag?: SAUPAN006046000
  • symbol: SACOL2486
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL2486 [new locus tag: SACOL_RS13025 ]
  • symbol: SACOL2486
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2542260..2542679
  • length: 420
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGTCGAAAAAGAAAATTTTAATATTAACTAGTATTATGTTAATCATATTAATTAGTGTT
    GCAGGTATCTATTTAAAAGTGAAATATGACGAAAAAGAAAAACAAAAAGCAATATACTAT
    AAAGAACAACAAGCGCGCATTACACTTTATCTCAAGCATAACACTAAAGAACCGAATACA
    ATCAAATCTGTACATTTCACAAACTCGGAAACAAGTCCTATGGGAAGTGCTGTGATTGAA
    GGTTACATAAATGAAAACAAAAAAGATAATTTTACTGCTTATGCTACACCAGAACATAAT
    TATCAATTTGGTGGTGCTATGATAGAAAGTGAAAAATTAAGCGAGTTACTAAAGCCAGCC
    AATCAGTTAAAATCACCAGATGATATAAAAAAAGAACTAAATAAAAAGAAGAGTCACTAA
    60
    120
    180
    240
    300
    360
    420

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL2486 [new locus tag: SACOL_RS13025 ]
  • symbol: SACOL2486
  • description: hypothetical protein
  • length: 139
  • theoretical pI: 9.9502
  • theoretical MW: 15936.4
  • GRAVY: -0.626619

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • FIG01108221: hypothetical protein
  • PFAM:
    no clan defined DUF1433; Protein of unknown function (DUF1433) (PF07252; HMM-score: 128.5)
    and 3 more
    Viral_Beta_CD; Viral Beta C/D like family (PF04530; HMM-score: 16)
    DUF4330; Domain of unknown function (DUF4330) (PF14221; HMM-score: 13.8)
    ABC-2 (CL0181) ABC2_membrane_3; ABC-2 family transporter protein (PF12698; HMM-score: 12)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 3.33
    • Cellwall Score: 3.33
    • Extracellular Score: 3.33
    • Internal Helix: 1
  • LocateP: N-terminally anchored (No CS)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: 0
    • N-terminally Anchored Score: 2
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.316387
    • TAT(Tat/SPI): 0.001491
    • LIPO(Sec/SPII): 0.072354
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSKKKILILTSIMLIILISVAGIYLKVKYDEKEKQKAIYYKEQQARITLYLKHNTKEPNTIKSVHFTNSETSPMGSAVIEGYINENKKDNFTAYATPEHNYQFGGAMIESEKLSELLKPANQLKSPDDIKKELNKKKSH

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: Signal peptide containing [1]
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int J Med Microbiol: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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