From AureoWiki
Jump to navigation Jump to search

FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002517
  • pan locus tag?: SAUPAN006195000
  • symbol: ptsG
  • pan gene symbol?: glcB
  • synonym:
  • product: glucose-specific PTS transporter subunit IIBC

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002517
  • symbol: ptsG
  • product: glucose-specific PTS transporter subunit IIBC
  • replicon: chromosome
  • strand: -
  • coordinates: 2521470..2523536
  • length: 2067
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    ATGTTTAAGAAATTGTTTGGACAATTGCAACGTATCGGTAAAGCATTAATGTTACCTGTT
    GCGATTTTACCAGCAGCTGGTATTTTATTAGCGTTTGGTAACGCAATGCACAACGAACAA
    TTAGTAGAAATTGCACCATGGTTAAAAAACGATATCATTGTAATGATTTCGTCGGTCATG
    GAAGCAGCAGGACAAGTTGTATTTGATAACTTGCCATTATTATTTGCAGTTGGTACAGCA
    CTTGGATTAGCAGGAGGAGACGGTGTTGCAGCATTAGCAGCGCTAGTAGGTTACTTAATT
    ATGAATGCAACAATGGGGAAAGTGTTGCACATTACAATTGATGACATTTTCTCATATGCC
    AAAGGGGCAAAAGAATTAAGTCAAGCAGCGAAAGAACCAGCACATGCTTTAGTATTAGGT
    ATTCCAACGTTACAAACGGGTGTGTTTGGCGGTATTATCATGGGTGCTTTAGCAGCATGG
    TGCTACAACAAATTTTATAACATTACACTACCACCATTTTTAGGATTCTTTGCAGGTAAA
    CGATTTGTACCGATTGTGACATCGGTCGTAGCAATTGCAACAGGTGTGGTTTTAAGCTTT
    GCGTGGCCACCAATTCAAGATGGATTAAATAGTTTATCGAATTTCTTATTAAATAAAAAT
    TTAACATTAACAACGTTTATATTCGGTATTATTGAACGCTCATTAATTCCATTTGGTTTA
    CATCATATTTTCTATTCACCATTCTGGTTTGAATTCGGAAGTTATACAAATCACGCAGGT
    GAATTAGTTCGAGGTGACCAACGTATTTGGATGGCACAATTGAAAGATGGCGTACCATTT
    ACTGCTGGTGCATTTACTACTGGTAAATATCCATTTATGATGTTTGGTTTACCAGCGGCA
    GCATTTGCTATTTATAAAAATGCACGACCAGAACGCAAAAAAGTCGTGGGTGGTTTAATG
    TTATCAGCAGGATTAACTGCATTTTTAACTGGTATCACTGAGCCATTAGAATTTTCATTC
    TTATTTGTAGCACCAGTACTTTATGGAATTCACGTATTATTAGCTGGTACATCATTCTTA
    GTAATGCATTTATTAGGCGTTAAAATTGGTATGACATTCTCAGGTGGTTTCATAGATTAT
    ATTTTATATGGTTTATTAAACTGGGATCGTTCACACGCATTATTAGTTATTCCAGTCGGT
    ATTGTATATGCTATCGTGTATTACTTCTTATTCGACTTTGCAATTCGTAAGTTTAAATTG
    AAAACACCAGGTCGTGAAGATGAAGAAACTGAAATTCGTAACTCTAGTGTCGCAAAATTA
    CCATTTGATGTCTTAGATGCAATGGGTGGAAAAGAAAACATTAAACATTTAGATGCATGT
    ATTACACGTCTGCGCGTAGAAGTGGTTGATAAATCAAAAGTAGATGTAGCAGGTATTAAA
    GCTTTAGGCGCATCAGGTGTATTAGAAGTTGGAAACAATATGCAAGCTATCTTTGGTCCA
    AAATCAGATCAAATTAAACATGATATGGCCAAGATTATGAGTGGTGAAATTACGAAACCA
    AGTGAAACGACAGTGACTGAAGAAATGTCAGATGAACCAGTTCACGTAGAAGCACTTGGA
    ACAACAGACATCTATGCACCAGGTATCGGTCAAATCATTCCATTATCAGAAGTACCTGAT
    CAAGTATTCGCTGGTAAAATGATGGGTGATGGTGTTGGCTTTATCCTTGAAAAAGGTGAA
    ATTGTAGCACCGTTTGATGGTACAGTGAAAACAATCTTCCCTACGAAACATGCAATAGGA
    TTAGAATCTGAAAGTGGTGTCGAAGTACTTATTCATATTGGTATCGATACAGTGAAACTG
    AATGGCGAAGGATTCGAAAGTCTGATTAACGTTGATGAAAAAGTAACACAAGGTCAAGCA
    TTAATGAAAGTGAATTTAGCATACTTGAAAGCGCACGCACCAAGCATCGTCACGCCTATG
    ATTATTACAAATCTTGAAAATAAAGAACTTGTCATTGAAGATGTACAAGATGCTGATCCT
    GGTAAATTAATTATGACAGTCAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2067

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_002517
  • symbol: PtsG
  • description: glucose-specific PTS transporter subunit IIBC
  • length: 688
  • theoretical pI: 6.13064
  • theoretical MW: 74391.8
  • GRAVY: 0.432267

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.1.199?  ExPASy
    Protein-N(pi)-phosphohistidine--D-glucose phosphotransferase [Protein]-N(pi)-phospho-L-histidine + D-glucose(Side 1) = [protein]-L-histidine + D-glucose 6-phosphate(Side 2)
  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-specific IIBC component (TIGR02002; EC 2.7.1.69; HMM-score: 850.2)
    and 13 more
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, N-acetylglucosamine-specific IIBC component (TIGR01998; EC 2.7.1.69; HMM-score: 451.9)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific IIBC component (TIGR02004; EC 2.7.1.69; HMM-score: 380.1)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, alpha-glucoside-specific IIBC component (TIGR02005; EC 2.7.1.69; HMM-score: 302.9)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 277.9)
    Signal transduction Signal transduction PTS PTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 277.9)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, IIBC component (TIGR02003; EC 2.7.1.69; HMM-score: 257.6)
    PTS system, beta-glucoside-specific IIABC component (TIGR01995; EC 2.7.1.69; HMM-score: 182.7)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose subfamily, IIA component (TIGR00830; HMM-score: 138.4)
    Signal transduction Signal transduction PTS PTS system, glucose subfamily, IIA component (TIGR00830; HMM-score: 138.4)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 71)
    Signal transduction Signal transduction PTS PTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 71)
    PTS system, sucrose-specific IIBC component (TIGR01996; EC 2.7.1.69; HMM-score: 55.4)
    PTS system, trehalose-specific IIBC component (TIGR01992; EC 2.7.1.69; HMM-score: 28.8)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    PTS_EIIC (CL0493) PTS_EIIC; Phosphotransferase system, EIIC (PF02378; HMM-score: 303.9)
    and 3 more
    Hybrid (CL0105) PTS_EIIA_1; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 (PF00358; HMM-score: 165.7)
    no clan defined PTS_EIIB; phosphotransferase system, EIIB (PF00367; HMM-score: 57.6)
    Hybrid (CL0105) RnfC_N; RnfC Barrel sandwich hybrid domain (PF13375; HMM-score: 17.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0007
    • Cytoplasmic Membrane Score: 0.9977
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0015
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.412118
    • TAT(Tat/SPI): 0.014658
    • LIPO(Sec/SPII): 0.041457
  • predicted transmembrane helices (TMHMM): 9

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFKKLFGQLQRIGKALMLPVAILPAAGILLAFGNAMHNEQLVEIAPWLKNDIIVMISSVMEAAGQVVFDNLPLLFAVGTALGLAGGDGVAALAALVGYLIMNATMGKVLHITIDDIFSYAKGAKELSQAAKEPAHALVLGIPTLQTGVFGGIIMGALAAWCYNKFYNITLPPFLGFFAGKRFVPIVTSVVAIATGVVLSFAWPPIQDGLNSLSNFLLNKNLTLTTFIFGIIERSLIPFGLHHIFYSPFWFEFGSYTNHAGELVRGDQRIWMAQLKDGVPFTAGAFTTGKYPFMMFGLPAAAFAIYKNARPERKKVVGGLMLSAGLTAFLTGITEPLEFSFLFVAPVLYGIHVLLAGTSFLVMHLLGVKIGMTFSGGFIDYILYGLLNWDRSHALLVIPVGIVYAIVYYFLFDFAIRKFKLKTPGREDEETEIRNSSVAKLPFDVLDAMGGKENIKHLDACITRLRVEVVDKSKVDVAGIKALGASGVLEVGNNMQAIFGPKSDQIKHDMAKIMSGEITKPSETTVTEEMSDEPVHVEALGTTDIYAPGIGQIIPLSEVPDQVFAGKMMGDGVGFILEKGEIVAPFDGTVKTIFPTKHAIGLESESGVEVLIHIGIDTVKLNGEGFESLINVDEKVTQGQALMKVNLAYLKAHAPSIVTPMIITNLENKELVIEDVQDADPGKLIMTVK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://aureowiki.med.uni-greifswald.de/index.php?title=JSNZ_002517&oldid=108158"