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FunGene: 08-OCT-2024
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: JSNZ_002586
- pan locus tag?: SAUPAN006303000
- symbol: JSNZ_002586
- pan gene symbol?: —
- synonym:
- product: hypothetical protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: JSNZ_002586
- symbol: JSNZ_002586
- product: hypothetical protein
- replicon: chromosome
- strand: +
- coordinates: 2592061..2592477
- length: 417
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID:
- RefSeq:
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361ATGCGTTTAAAAGTATTGTTCCATTTCATTGCTGCTATTTTCATATCATTCATGTTGCTA
TGGATGACCATGTTGTTTGACTTAATAAGCAATCAATCACATTTAAAAGCTTTATTATTG
AATTTAGATTTTCTAATTCCTTCTGACAATACACCATATATTCTAGAAATAATATGTCAC
TTACTAATTGGTAGCGTCATTTATTTTGTATTTGTGTTGGTGTTTCATACTTCTAAAAGG
CTTTACTATCTATGTTATATCCCTTTATTTTTCTTATTTATAGCATTGTATCCCTTTTTA
GTATTTATTGCGCAACGTCCAATTTTTCAATTTAGTGTGACAGAATTAATCGGTTGGATT
ATTACACATATTTTCTTTATGTCATTAATGGCGTTAGTCATACCTAGAATAAAATAA60
120
180
240
300
360
417
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: JSNZ_002586
- symbol: JSNZ_002586
- description: hypothetical protein
- length: 138
- theoretical pI: 9.11151
- theoretical MW: 16376
- GRAVY: 1.2913
⊟Function[edit | edit source]
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 4
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0.0004
- Cytoplasmic Membrane Score: 0.9993
- Cell wall & surface Score: 0
- Extracellular Score: 0.0003
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.047783
- TAT(Tat/SPI): 0.000325
- LIPO(Sec/SPII): 0.011171
- predicted transmembrane helices (TMHMM): 4
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
- MRLKVLFHFIAAIFISFMLLWMTMLFDLISNQSHLKALLLNLDFLIPSDNTPYILEIICHLLIGSVIYFVFVLVFHTSKRLYYLCYIPLFFLFIALYPFLVFIAQRPIFQFSVTELIGWIITHIFFMSLMALVIPRIK
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulators: CodY (repression) regulon, SigB (activation) regulon
CodY (TF) important in Amino acid metabolism; transcription unit predicted or transferred from N315 and NCTC8325 SigB (sigma factor) controlling a large regulon involved in stress/starvation response and adaptation; transcription unit predicted or transferred from N315 and NCTC8325 [1] [2] [3] other strains
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Markus Bischoff, Paul Dunman, Jan Kormanec, Daphne Macapagal, Ellen Murphy, William Mounts, Brigitte Berger-Bächi, Steven Projan
Microarray-based analysis of the Staphylococcus aureus sigmaB regulon.
J Bacteriol: 2004, 186(13);4085-99
[PubMed:15205410] [WorldCat.org] [DOI] (P p) - ↑ Jan Pané-Farré, Beate Jonas, Konrad Förstner, Susanne Engelmann, Michael Hecker
The sigmaB regulon in Staphylococcus aureus and its regulation.
Int J Med Microbiol: 2006, 296(4-5);237-58
[PubMed:16644280] [WorldCat.org] [DOI] (P p) - ↑ Bettina Schulthess, Dominik A Bloes, Patrice François, Myriam Girard, Jacques Schrenzel, Markus Bischoff, Brigitte Berger-Bächi
The σB-dependent yabJ-spoVG operon is involved in the regulation of extracellular nuclease, lipase, and protease expression in Staphylococcus aureus.
J Bacteriol: 2011, 193(18);4954-62
[PubMed:21725011] [WorldCat.org] [DOI] (I p)