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COLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40
NCBI: 06-JUL-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_0404 [new locus tag: NWMN_RS02285 ]
- pan locus tag?:
- symbol: lpl2nm
- pan gene symbol?: —
- synonym:
- product: tandem lipoprotein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_0404 [new locus tag: NWMN_RS02285 ]
- symbol: lpl2nm
- product: tandem lipoprotein
- replicon: chromosome
- strand: +
- coordinates: 454025..454825
- length: 801
- essential: unknown
⊟Accession numbers[edit | edit source]
- Gene ID: 5332090 NCBI
- RefSeq: YP_001331438 NCBI
- BioCyc:
- MicrobesOnline: 3705935 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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781ATGCGATATCTAAAAAAGCTTGCATGGTTCATAAGTGTTATTATTTTGGGCATTTTTATA
ATAGGTTGTGATAGTTCAAGCGATACTGGGGAAAAAGCAAAAGAAGATTCAAAGGAAGAA
CAAATCAAAAAGAGCTTTGCGAAAACATTAGATATGTATCCAATTAAGAATCTCGAGGAC
TTATATGACGAAGAAGGATATCGAGATAGCGAATTTAAAAAAGGTGACAAAGGGATGTGG
ACGATATATACAGATTTCGCCAAAAGTAATAAACCGGGTGTATTAGATAATGAAGGTATG
ATTTTAAATTTGGATAGAAATACACGTACGGCCAAGGGATATTATTTTGTAGATACTATA
TATGACAATCATGAAAACTCTTATAGTAAAAATTATAGAGTTGAGATGAAAAACAATAAA
ATTATTTTATTAGACAAGGTGGAAGATCAAAAACTTAAAGAAAGAATAGAAAACTTTAAA
TTTTTCGGACAATATGCCGATTTCAAGAGTTTGAAAAGTTACAACAATGGCGACGTTTCA
ATTAATAGTAATGTTCCAAGTTATGACGCGAAATTTAAAATGAGTAATAAAGATGAAAAT
GTTAAGCAATTAAGAAGTCGTTATAACATTCCTACTGAAAAAGCTCCAATATTAAAAATG
CATATTGATGGGGACTTAAAAGGCAGTTCCGTTGGATATAAAAAGTTAGAAATAGACTTT
TCAAAAGAAGAAAATAGCGAATTATCAGTAGTCGATTCATTAAATTTTCAGCCTGCCAAA
AAAAATAAAGATGATGAATGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_0404 [new locus tag: NWMN_RS02285 ]
- symbol: Lpl2nm
- description: tandem lipoprotein
- length: 266
- theoretical pI: 6.58167
- theoretical MW: 30887.6
- GRAVY: -0.853007
⊟Function[edit | edit source]
- TIGRFAM: Staphylococcus tandem lipoproteins (TIGR01742; HMM-score: 385.5)
- TheSEED:
- PFAM: LolA_LolB (CL0048) DUF576; Csa1 family (PF04507; HMM-score: 366.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 3.33
- Cellwall Score: 3.33
- Extracellular Score: 3.33
- Internal Helix: 1
- LocateP: Lipid anchored
- Prediction by SwissProt Classification: Extracellular
- Pathway Prediction: Sec-(SPII)
- Intracellular possibility: 0.17
- Signal peptide possibility: 0
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: IFIIGCD
- SignalP: Signal peptide LIPO(Sec/SPII) length 22 aa
- SP(Sec/SPI): 0.00056
- TAT(Tat/SPI): 0.000046
- LIPO(Sec/SPII): 0.999244
- Cleavage Site: CS pos: 22-23. IIG-CD. Pr: 0.9996
- predicted transmembrane helices (TMHMM): 1
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MRYLKKLAWFISVIILGIFIIGCDSSSDTGEKAKEDSKEEQIKKSFAKTLDMYPIKNLEDLYDEEGYRDSEFKKGDKGMWTIYTDFAKSNKPGVLDNEGMILNLDRNTRTAKGYYFVDTIYDNHENSYSKNYRVEMKNNKIILLDKVEDQKLKERIENFKFFGQYADFKSLKSYNNGDVSINSNVPSYDAKFKMSNKDENVKQLRSRYNIPTEKAPILKMHIDGDLKGSSVGYKKLEIDFSKEENSELSVVDSLNFQPAKKNKDDE
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: SaeR (activation) regulon
SaeR (TF) important in Virulence; RegPrecise transcription unit transferred from N315 data RegPrecise
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: no data available
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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