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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40
NCBI: 06-JUL-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_0405
- pan locus tag?: SAUPAN000587000
- symbol: NWMN_0405
- pan gene symbol?: —
- synonym:
- product: tandem lipoprotein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_0405
- symbol: NWMN_0405
- product: tandem lipoprotein
- replicon: chromosome
- strand: +
- coordinates: 454844..455317
- length: 474
- essential: unknown
⊟Accession numbers[edit | edit source]
- Gene ID: 5332091 NCBI
- RefSeq: YP_001331439 NCBI
- BioCyc:
- MicrobesOnline: 3705936 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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421ATGTGGTCAATAAAAAGAATTGGAATGTACACAAATGTTATAATTTTGAGCGTTTTTATA
ATAGGTTGTGATAGTTCAAGCAATAATGCAGAAAATCAAAGAGAAGACTCAAAAGAAGAA
CAAATCAAAAAGAGCTTTGCGAAAACGTTAGATATGTACCCTATTAAGAATCTCGAGGAT
TTATATGACAAAGAAGGATATCGTGATGGTGAGTTTGAAAAAGGCGATAAGGGGACGTGG
GTATTGTATTCAGCTATGGTATCACAACCAAAAGGCGAGAGTTTAAAATCACGAGGAATG
ATATTAAAGTTAGATAGAAATAAGAGAACTGCTAAAGGAAGTTATATTATTAGAGAATTG
AAAGAAGATAAAAATCATGATGTTCAAAAAAATGAAAAGAAATATCCAGTGAAATTGGTG
AATAATAGGATAGTTTTGATAAAAGATGTTAAAGACAAAAAGTTAAAAAAATGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_0405
- symbol: NWMN_0405
- description: tandem lipoprotein
- length: 157
- theoretical pI: 10.1157
- theoretical MW: 18296
- GRAVY: -0.864968
⊟Function[edit | edit source]
- TIGRFAM: Staphylococcus tandem lipoproteins (TIGR01742; HMM-score: 227.1)
- TheSEED:
- PFAM: LolA_LolB (CL0048) DUF576; Csa1 family (PF04507; HMM-score: 207.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 0.67
- Signal peptide possibility: -0.5
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: Signal peptide LIPO(Sec/SPII) length 22 aa
- SP(Sec/SPI): 0.00068
- TAT(Tat/SPI): 0.000106
- LIPO(Sec/SPII): 0.998884
- Cleavage Site: CS pos: 22-23. IIG-CD. Pr: 0.9996
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MWSIKRIGMYTNVIILSVFIIGCDSSSNNAENQREDSKEEQIKKSFAKTLDMYPIKNLEDLYDKEGYRDGEFEKGDKGTWVLYSAMVSQPKGESLKSRGMILKLDRNKRTAKGSYIIRELKEDKNHDVQKNEKKYPVKLVNNRIVLIKDVKDKKLKK
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: SaeR (activation) regulon
SaeR (TF) important in Virulence; RegPrecise transcription unit transferred from N315 data RegPrecise
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: no data available
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.