From AureoWiki
Jump to navigation Jump to search
PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary[edit | edit source]

  • pan ID?: SAUPAN000587000
  • symbol?: —
  • synonym:
  • description?: tandem lipoprotein

      descriptions from strain specific annotations:

    • tandem lipoprotein
    • pseudogene
    • staphylococcal tandem lipoprotein
    • Tandem lipo protein within Pathogenicity island
    • truncated staphylococcal tandem lipoprotein
  • strand?: +
  • coordinates?: 678827..688820
  • synteny block?: BlockID0002880
  • occurrence?: in 24% of 34 strains

⊟Additional information (user-provided)[edit | edit source]

tilA (lpl) : tandem TslA phospholipase immunity lipoprotein paralogue pseudogene [1]

• This locus is highly prone to recombination leading to gene duplication / loss. Gene nomenclature is confusing and appears to be numbered sequentially by position in the genome and is not intended to show homology between strains (e.g. the first instance of tilA/lpl in COL may have the greatest homology with the sixth instance in FPR3757 but the gene names would still be different [i.e. tilA1/lpl1 and tilA6/lpl6 in COL and FPR3757, respectively]). Likewise, pseudogenes are frequent and assigned gene nomenclature in this locus. As appropriate, please append a numeral to the gene names provided here consistent with the number of gene duplications in your genome of interest.

⊟Orthologs[edit | edit source]

    COL:
    —
    N315:
    —
    NCTC8325:
    —
    Newman:
    USA300_FPR3757:
    JSNZ:
    —
    04-02981:
    —
    08BA02176:
    —
    11819-97:
    MS7_0415
    6850:
    —
    71193:
    —
    ECT-R 2:
    —
    ED133:
    —
    ED98:
    —
    HO 5096 0412:
    —
    JH1:
    —
    JH9:
    —
    JKD6008:
    SAA6008_00440
    JKD6159:
    SAA6159_00392 (lpl3)
    LGA251:
    —
    M013:
    M013TW_0399
    MRSA252:
    —
    MSHR1132:
    —
    MSSA476:
    —
    Mu3:
    —
    Mu50:
    —
    MW2:
    —
    RF122:
    —
    ST398:
    —
    T0131:
    SAT0131_00476 (fhs)
    TCH60:
    —
    TW20:
    —
    USA300_TCH1516:
    USA300HOU_0440
    VC40:
    —

⊟Genome Viewer[edit | edit source]

Newman
USA300_FPR3757

⊟Alignments[edit | edit source]

  • alignment of orthologues:

⊟Literature[edit | edit source]

  1. ↑ Stephen R Garrett, Nicole Mietrach, Justin Deme, Alina Bitzer, Yaping Yang, Fatima R Ulhuq, Dorothee Kretschmer, Simon Heilbronner, Terry K Smith, Susan M Lea, Tracy Palmer
    A type VII-secreted lipase toxin with reverse domain arrangement.
    Nat Commun: 2023, 14(1);8438
    [PubMed:38114483] [WorldCat.org] [DOI] (I e)
    Stephen R Garrett, Giuseppina Mariano, Jo Dicks, Tracy Palmer
    Homologous recombination between tandem paralogues drives evolution of a subset of type VII secretion system immunity genes in firmicute bacteria.
    Microb Genom: 2022, 8(8);
    [PubMed:35960642] [WorldCat.org] [DOI] (I p)