PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 06-JUL-2013

⊟Summary

• organism: Staphylococcus aureus Newman
• locus tag: NWMN_0702 [new locus tag: NWMN_RS03980 ]
• pan locus tag^?: SAUPAN002636000
• symbol: NWMN_0702
• pan gene symbol^?: sstA
• synonym:
• product: ferrichrome ABC transporter permease

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: NWMN_0702 [new locus tag: NWMN_RS03980 ]
• symbol: NWMN_0702
• product: ferrichrome ABC transporter permease
• replicon: chromosome
• strand: +
• coordinates: 788526..789497
• length: 972
• essential: unknown other strains

⊟Accession numbers

• Gene ID: 5332209 NCBI
• RefSeq: YP_001331736 NCBI
• BioCyc:
• MicrobesOnline: 3706249 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
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  961
  
  ATGAAGTATTTATTAAAGGGAAATATTTTGCTTCTATTACTAATATTGTTGACAATTATT
  TCGTTGTTCATAGGTGTGAGTGAACTATCAATTAAAGATTTACTACATTTAACTGAGTCA
  CAGCGGAATATTTTATTCTCAAGCCGAATACCAAGGACGATGAGTATTTTAATTGCTGGA
  AGTTCGTTGGCTTTAGCAGGCTTGATAATGCAACAAATGATGCAAAATAAGTTTGTTAGT
  CCGACTACAGCTGGAACGATGGAATGGGCTAAACTAGGTATTTTAATTGCTTTATTGTTC
  TTTCCAACCGGTCATATTTTATTAAAACTAGTATTTGCTGTTATTTGCAGTATTTGCGGT
  ACGTTTTTATTTGTTAAAATCATTGATTTTATAAAAGTGAAAGATGTCATTTTTGTACCG
  CTTTTAGGAATTATGATGGGTGGGATTGTTGCAAGTTTCACAACCTTCATCTCATTGCGC
  ACGAATGCTGTTCAAAGCATTGGTAACTGGCTTAACGGGAACTTTGCCATTATCACAAGT
  GGACGCTATGAAATTTTATATTTAAGTATTCCTCTTTTAGCATTGACATATCTTTTTGCT
  AATCATTTCACGATTGTAGGAATGGGTAAAGACTTTACTAATAATTTAGGTTTGAGTTAC
  GAAAAATTAATTAACATCGCATTGTTTATTACTGCAACTATTACAGCATTGGTAGTGGTG
  ACTGTTGGAACATTACCGTTCTTAGGACTAGTAATACCAAATATTATTTCAATTTATCGA
  GGTGATCATTTGAAAAATGCTATCCCTCATACGATGATGTTAGGTGCCATCTTTGTATTA
  TTTTCTGATATAGTTGGCAGAATTGTTGTTTATCCATATGAAATAAATATTGGTTTAACA
  ATAGGTGTATTTGGAACAATCATTTTCCTTATCTTGCTTATGAAAGGTAGGAAAAATTAT
  GCGCAACAATAA
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⊟Protein

⊟General

• locus tag: NWMN_0702 [new locus tag: NWMN_RS03980 ]
• symbol: NWMN_0702
• description: ferrichrome ABC transporter permease
• length: 323
• theoretical pI: 10.1221
• theoretical MW: 35581.9
• GRAVY: 1.00279

⊟Function

• TIGRFAM:
  proposed F420-0 ABC transporter, permease protein (TIGR03869; HMM-score: 93.3)
• TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
• PFAM:
  Membrane_trans (CL0142) FecCD; FecCD transport family (PF01032; HMM-score: 214.1)
  and 1 more
  no clan defined DUF2367; Uncharacterized conserved protein (DUF2367) (PF10164; HMM-score: 13.7)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 8
• LocateP: Multi-transmembrane
  • Prediction by SwissProt Classification: Membrane
  • Pathway Prediction: Sec-(SPI)
  • Intracellular possibility: 0
  • Signal peptide possibility: 1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.036831
  • TAT(Tat/SPI): 0.000302
  • LIPO(Sec/SPII): 0.035584
• predicted transmembrane helices (TMHMM): 8

⊟Accession numbers

• GI: 151220914 NCBI
• RefSeq: YP_001331736 NCBI
• UniProt: A0A0H3K7I5 UniProt

⊟Protein sequence

• MKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNILFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFPTGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGLSYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGAIFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ

⊟Experimental data

• experimentally validated: data available for NCTC8325
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: NWMN_0702 > NWMN_0703 > NWMN_0704 > NWMN_0705

⊟Regulation

• regulator: Fur* (repression) regulon

  Fur*

  (TF)

  important in Iron homeostasis; RegPrecise

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications