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NCBI: 06-JUL-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_1406 [new locus tag: NWMN_RS07935 ]
- pan locus tag?: SAUPAN004031000
- symbol: NWMN_1406
- pan gene symbol?: fur
- synonym:
- product: iron uptake regulatory protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_1406 [new locus tag: NWMN_RS07935 ]
- symbol: NWMN_1406
- product: iron uptake regulatory protein
- replicon: chromosome
- strand: -
- coordinates: 1574730..1575179
- length: 450
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 5330834 NCBI
- RefSeq: YP_001332440 NCBI
- BioCyc:
- MicrobesOnline: 3706958 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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421TTGGAAGAACGATTAAATCGCGTTAAGCAACAATTACAACAATCATCATATAAGCTAACG
CCACAACGCGAAGCTACTGTTAGAGTTCTAATTGAAAATGAAAAAGATCATCTAAGTGCT
GAAGACGTATATCTGAAAGTAAAAGATAAAGCGCCTGAAATTGGCTTGGCGACAGTATAC
AGAACGTTAGAGTTGTTAGCTGAACTAAAAGTTGTCGACAAAATTAACTTTGGTGATGGC
GTCGCTCGTTTTGATTTAAGAAAAGAAGGCGCAAAACATTTCCACCATCATTTAGTATGT
ATGGAATGTGGTCGTGTAGATGAAATCGATGAAGATTTGTTACCAGAAGTTGAAAATCGA
GTTGAAAATGAGTTCAATTTTAAAATTTTAGATCATCGTTTAACTTTCCATGGTGTGTGT
GAAACGTGCCAAGCTAAAGGTAAAGGATAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_1406 [new locus tag: NWMN_RS07935 ]
- symbol: NWMN_1406
- description: iron uptake regulatory protein
- length: 149
- theoretical pI: 6.15861
- theoretical MW: 17243.6
- GRAVY: -0.575168
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
- PFAM: HTH (CL0123) FUR; Ferric uptake regulator family (PF01475; HMM-score: 131.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effector: Iron ion (Fe2+)
- genes regulated by Fur*, TF important in Iron homeostasisRegPrecisetranscription units transferred from N315 data RegPrecise
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular possibility: 1
- Signal peptide possibility: -1
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001453
- TAT(Tat/SPI): 0.000154
- LIPO(Sec/SPII): 0.000214
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MEERLNRVKQQLQQSSYKLTPQREATVRVLIENEKDHLSAEDVYLKVKDKAPEIGLATVYRTLELLAELKVVDKINFGDGVARFDLRKEGAKHFHHHLVCMECGRVDEIDEDLLPEVENRVENEFNFKILDHRLTFHGVCETCQAKGKG
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- data available for N315
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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