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NCBI: 06-JUL-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_0618 [new locus tag: NWMN_RS03515 ]
- pan locus tag?: SAUPAN002527000
- symbol: fhuG
- pan gene symbol?: fhuG
- synonym:
- product: ferrichrome transport permease fhuG
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_0618 [new locus tag: NWMN_RS03515 ]
- symbol: fhuG
- product: ferrichrome transport permease fhuG
- replicon: chromosome
- strand: +
- coordinates: 700323..701339
- length: 1017
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 5331909 NCBI
- RefSeq: YP_001331652 NCBI
- BioCyc:
- MicrobesOnline: 3706165 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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961ATGATTAGTTCAAATAATAAACGCAGACAATTGATAGCACTGGCTGTTTTTAGCATTCTA
CTATTTCTAGGTTGTACTTGGAGTATTACCTCAGGTGAATACAACATACCTGTTGAAAGA
TTTTTCAAAACTTTAATTGGACAAGGTGATGCCATTGATGAGTTAATCTTATTAGATTTC
AGGTTACCTCGGATGATGATTACTATTTTGGCTGGCGCAGCGCTTAGTATTAGTGGTGCA
ATAGTGCAAAGTGTCACAAAAAATCCAATAGCTGAACCAGGTATATTAGGTATTAACGCA
GGTGGCGGATTTGCAATCGCATTATTTATTGCAATTGGTAAAATTAATGCTGACAACTTT
GTTTATGTACTGCCGTTAATAAGTATACTAGGTGGTATCACCACTGCATTGATTATTTTT
ATTTTCAGTTTTAATAAAAATGAAGGTGTTACACCTGCGAGTATGGTATTAATAGGTGTA
GGTTTACAAACAGCATTATATGGTGGCTCAATTACAATTATGTCAAAATTTGATGATAAG
CAATCTGATTTCATCGCTGCTTGGTTTGCAGGTAATATTTGGGGTGACGAATGGCCATTT
GTCATTGCATTTTTACCGTGGGTGTTGATTATTATTCCTTACTTACTATTTAAATCGAAT
ACACTAAATATTATTCATACGGGTGATAATATTGCACGAGGTCTAGGTGTAAGGTTAAGC
AGAGAACGTTTAATATTATTCTTTATCGCAGTGATGTTATCATCTGCTGCTGTAGCAGTA
GCAGGTTCAATTTCGTTTATCGGATTAATGGGTCCGCATATTGCCAAACGTATCGTTGGA
CCACGTCACCAGTTGTTTTTACCAATTGCCATTTTAGTAGGGGCATGTTTACTTGTTATA
GCTGATACAATTGGCAAAATTGTATTACAACCAGGTGGGGTTCCAGCAGGTATTGTCGTA
GCAATTATTGGTGCACCGTATTTCTTATATTTAATGTACAAAACGAAAAATGTATAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_0618 [new locus tag: NWMN_RS03515 ]
- symbol: FhuG
- description: ferrichrome transport permease fhuG
- length: 338
- theoretical pI: 9.75188
- theoretical MW: 36278.1
- GRAVY: 0.897633
⊟Function[edit | edit source]
- TIGRFAM: proposed F420-0 ABC transporter, permease protein (TIGR03869; HMM-score: 163.8)and 1 moreEnergy metabolism Electron transport cytochrome c oxidase, subunit IVB (TIGR02908; EC 1.9.3.1; HMM-score: 4.6)
- TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
- PFAM: Membrane_trans (CL0142) FecCD; FecCD transport family (PF01032; HMM-score: 291.9)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 9
- LocateP: Multi-transmembrane
- Prediction by SwissProt Classification: Membrane
- Pathway Prediction: Sec-(SPI)
- Intracellular possibility: 0
- Signal peptide possibility: 0.5
- N-terminally Anchored Score: -1
- Predicted Cleavage Site: No CleavageSite
- SignalP: Signal peptide LIPO(Sec/SPII) length 24 aa
- SP(Sec/SPI): 0.01306
- TAT(Tat/SPI): 0.003282
- LIPO(Sec/SPII): 0.973835
- Cleavage Site: CS pos: 24-25. FLG-CT. Pr: 0.9727
- predicted transmembrane helices (TMHMM): 9
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MISSNNKRRQLIALAVFSILLFLGCTWSITSGEYNIPVERFFKTLIGQGDAIDELILLDFRLPRMMITILAGAALSISGAIVQSVTKNPIAEPGILGINAGGGFAIALFIAIGKINADNFVYVLPLISILGGITTALIIFIFSFNKNEGVTPASMVLIGVGLQTALYGGSITIMSKFDDKQSDFIAAWFAGNIWGDEWPFVIAFLPWVLIIIPYLLFKSNTLNIIHTGDNIARGLGVRLSRERLILFFIAVMLSSAAVAVAGSISFIGLMGPHIAKRIVGPRHQLFLPIAILVGACLLVIADTIGKIVLQPGGVPAGIVVAIIGAPYFLYLMYKTKNV
⊟Experimental data[edit | edit source]
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: fhuA > fhuB > fhuG
⊟Regulation[edit | edit source]
- regulator: Fur* (repression) regulon
Fur* (TF) important in Iron homeostasis; RegPrecise transcription unit transferred from N315 data RegPrecise
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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