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NCBI: 06-JUL-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1067 [new locus tag: NWMN_RS06030 ]
  • pan locus tag?: SAUPAN003398000
  • symbol: NWMN_1067
  • pan gene symbol?: flr
  • synonym:
  • product: formyl peptide receptor-like 1 inhibitory protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_1067 [new locus tag: NWMN_RS06030 ]
  • symbol: NWMN_1067
  • product: formyl peptide receptor-like 1 inhibitory protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1171087..1171488
  • length: 402
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGAAAAAAAATATCACAAAAACTATTATCGCATCTACAGTAATCGCTGCAGGTCTTTTA
    ACTCAAACTAATGATGCTAAAGCTTTCTTTAGTTATGAATGGAAAGGTTTAGAAATCGCA
    AAAAATTTAGCAGATCAAGCTAAAAAGGACGATGAACGTATTGATAAGTTAATGAAAGAG
    TCTGATAAAAATCTAACTCCTTACAAAGCTGAAACTGTTAATGATCTGTACCTTATTGTT
    AAAAAATTAAGCCAAGGTGATGTGAAGAAAGCAGTTGTCAGAATTAAAGATGATGGTCCT
    AGAGATTACTATACTTTTGACTTAACTCGTCCTTTAGAAGAGAACAGAAAAAATATTAAA
    GTTGTTAAAAACGGTGAAATCGACTCGATTACTTGGTATTAA
    60
    120
    180
    240
    300
    360
    402

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_1067 [new locus tag: NWMN_RS06030 ]
  • symbol: NWMN_1067
  • description: formyl peptide receptor-like 1 inhibitory protein
  • length: 133
  • theoretical pI: 9.68102
  • theoretical MW: 15260.4
  • GRAVY: -0.637594

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined FPRL1_inhibitor; Formyl peptide receptor-like 1 inhibitory protein (PF16104; HMM-score: 232.8)
    and 1 more
    Ubiquitin (CL0072) CHIPS; Chemotaxis-inhibiting protein CHIPS (PF11434; HMM-score: 15.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 3.33
    • Cellwall Score: 3.33
    • Extracellular Score: 3.33
    • Internal Helices: 0
  • LocateP: Secretory(released) (with CS)
    • Prediction by SwissProt Classification: Extracellular
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: -0.17
    • Signal peptide possibility: 1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: NDAKAFFS
  • SignalP: Signal peptide SP(Sec/SPI) length 28 aa
    • SP(Sec/SPI): 0.959873
    • TAT(Tat/SPI): 0.002874
    • LIPO(Sec/SPII): 0.006357
    • Cleavage Site: CS pos: 28-29. AKA-FF. Pr: 0.8854
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDDGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]