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NCBI: 10-JUN-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus COL
- locus tag: SACOL1166 [new locus tag: SACOL_RS05960 ]
- pan locus tag?: SAUPAN003398000
- symbol: SACOL1166
- pan gene symbol?: flr
- synonym:
- product: formyl peptide receptor-like 1 inhibitory protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SACOL1166 [new locus tag: SACOL_RS05960 ]
- symbol: SACOL1166
- product: formyl peptide receptor-like 1 inhibitory protein
- replicon: chromosome
- strand: -
- coordinates: 1174896..1175297
- length: 402
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 3238392 NCBI
- RefSeq: YP_186029 NCBI
- BioCyc: see SACOL_RS05960
- MicrobesOnline: 912633 MicrobesOnline
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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361ATGAAAAAAAATATCACAAAAACTATTATCGCATCTACAGTAATCGCTGCAGGTCTTTTA
ACTCAAACTAATGATGCTAAAGCTTTCTTTAGTTATGAATGGAAAGGTTTAGAAATCGCA
AAAAATTTAGCAGATCAAGCTAAAAAGGACGATGAACGTATTGATAAGTTAATGAAAGAG
TCTGATAAAAATCTAACTCCTTACAAAGCTGAAACTGTTAATGATCTGTACCTTATTGTT
AAAAAATTAAGCCAAGGTGATGTGAAGAAAGCAGTTGTCAGAATTAAAGATGGTGGTCCT
AGAGATTACTATACTTTTGACTTAACTCGTCCTTTAGAAGAGAACAGAAAAAATATTAAA
GTTGTTAAAAACGGTGAAATCGACTCGATTACTTGGTATTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SACOL1166 [new locus tag: SACOL_RS05960 ]
- symbol: SACOL1166
- description: formyl peptide receptor-like 1 inhibitory protein
- length: 133
- theoretical pI: 9.83172
- theoretical MW: 15202.4
- GRAVY: -0.614286
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED :
- FIG017917: hypothetical protein
- PFAM: no clan defined FPRL1_inhibitor; Formyl peptide receptor-like 1 inhibitory protein (PF16104; HMM-score: 236.5)and 2 moreUbiquitin (CL0072) CHIPS; Chemotaxis-inhibiting protein CHIPS (PF11434; HMM-score: 14.7)no clan defined YlzJ; YlzJ-like protein (PF14035; HMM-score: 12.2)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 3.33
- Cellwall Score: 3.33
- Extracellular Score: 3.33
- Internal Helices: 0
- LocateP: Secretory(released) (with CS)
- Prediction by SwissProt Classification: Extracellular
- Pathway Prediction: Sec-(SPI)
- Intracellular possibility: -0.17
- Signal peptide possibility: 1
- N-terminally Anchored Score: -1
- Predicted Cleavage Site: NDAKAFFS
- SignalP: Signal peptide SP(Sec/SPI) length 28 aa
- SP(Sec/SPI): 0.959873
- TAT(Tat/SPI): 0.002874
- LIPO(Sec/SPII): 0.006357
- Cleavage Site: CS pos: 28-29. AKA-FF. Pr: 0.8854
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY
⊟Experimental data[edit | edit source]
- experimentally validated: PeptideAtlas
- protein localization: Cytoplasmic [1]
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
PLoS One: 2009, 4(12);e8176
[PubMed:19997597] [WorldCat.org] [DOI] (I e)