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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL1166 [new locus tag: SACOL_RS05960 ]
  • pan locus tag?: SAUPAN003398000
  • symbol: SACOL1166
  • pan gene symbol?: flr
  • synonym:
  • product: formyl peptide receptor-like 1 inhibitory protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SACOL1166 [new locus tag: SACOL_RS05960 ]
  • symbol: SACOL1166
  • product: formyl peptide receptor-like 1 inhibitory protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1174896..1175297
  • length: 402
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGAAAAAAAATATCACAAAAACTATTATCGCATCTACAGTAATCGCTGCAGGTCTTTTA
    ACTCAAACTAATGATGCTAAAGCTTTCTTTAGTTATGAATGGAAAGGTTTAGAAATCGCA
    AAAAATTTAGCAGATCAAGCTAAAAAGGACGATGAACGTATTGATAAGTTAATGAAAGAG
    TCTGATAAAAATCTAACTCCTTACAAAGCTGAAACTGTTAATGATCTGTACCTTATTGTT
    AAAAAATTAAGCCAAGGTGATGTGAAGAAAGCAGTTGTCAGAATTAAAGATGGTGGTCCT
    AGAGATTACTATACTTTTGACTTAACTCGTCCTTTAGAAGAGAACAGAAAAAATATTAAA
    GTTGTTAAAAACGGTGAAATCGACTCGATTACTTGGTATTAA
    60
    120
    180
    240
    300
    360
    402

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SACOL1166 [new locus tag: SACOL_RS05960 ]
  • symbol: SACOL1166
  • description: formyl peptide receptor-like 1 inhibitory protein
  • length: 133
  • theoretical pI: 9.83172
  • theoretical MW: 15202.4
  • GRAVY: -0.614286

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • FIG017917: hypothetical protein
  • PFAM:
    no clan defined FPRL1_inhibitor; Formyl peptide receptor-like 1 inhibitory protein (PF16104; HMM-score: 236.5)
    and 2 more
    Ubiquitin (CL0072) CHIPS; Chemotaxis-inhibiting protein CHIPS (PF11434; HMM-score: 14.7)
    no clan defined YlzJ; YlzJ-like protein (PF14035; HMM-score: 12.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 3.33
    • Cellwall Score: 3.33
    • Extracellular Score: 3.33
    • Internal Helices: 0
  • LocateP: Secretory(released) (with CS)
    • Prediction by SwissProt Classification: Extracellular
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: -0.17
    • Signal peptide possibility: 1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: NDAKAFFS
  • SignalP: Signal peptide SP(Sec/SPI) length 28 aa
    • SP(Sec/SPI): 0.959873
    • TAT(Tat/SPI): 0.002874
    • LIPO(Sec/SPII): 0.006357
    • Cleavage Site: CS pos: 28-29. AKA-FF. Pr: 0.8854
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKKNITKTIIASTVIAAGLLTQTNDAKAFFSYEWKGLEIAKNLADQAKKDDERIDKLMKESDKNLTPYKAETVNDLYLIVKKLSQGDVKKAVVRIKDGGPRDYYTFDLTRPLEENRKNIKVVKNGEIDSITWY

⊟Experimental data[edit | edit source]

  • experimentally validated: PeptideAtlas
  • protein localization: Cytoplasmic [1]
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
    A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
    PLoS One: 2009, 4(12);e8176
    [PubMed:19997597] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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