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NCBI: 06-JUL-2013
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_1082 [new locus tag: NWMN_RS06130 ]
- pan locus tag?: SAUPAN003435000
- symbol: eta
- pan gene symbol?: —
- synonym:
- product: exfoliative toxin A
⊟Additional information (user-provided)[edit | edit source]
Please note that NWMN_1082 is falsely annotated as exfoliative toxin A (eta) in the original genome annotation submitted to RefSeq.
For an eta sequence please refer to the GenBank ID M17357 [1]
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: NWMN_1082 [new locus tag: NWMN_RS06130 ]
- symbol: eta
- product: exfoliative toxin A
- replicon: chromosome
- strand: -
- coordinates: 1186112..1187059
- length: 948
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Gene ID: 5330666 NCBI
- RefSeq: YP_001332116 NCBI
- BioCyc:
- MicrobesOnline: 3706633 MicrobesOnline
⊟Phenotype[edit | edit source]
⊟Additional information (user-provided)[edit | edit source]
⊟DNA sequence[edit | edit source]
- 1
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901ATGAGACTTCAAAAAGCACCTCTAGTAACGTCAGGACTAGTCTTAGGATTATTAGGCCTG
GGTAATCTATTAAAAGACTTATCTCTTACTTTAAACGCTGTTTGCGGAATCTTTGCTTTC
TTGATTTGGATTCACCTTTTATGTACTATGATCAAATATTTTAATAATGTGAAAGAACAA
TTAAACAGTCCTCTAGTTTCATCAGTGTTCACAACATTTTTCATGTCTGGCTTTTTAGGT
ACTACTTATTTAAATACATTTTTTAGTAACATAACTTTTATCAATAGCTTAATAACGCCT
ATTTGGATTTTATGCCTTGTGGGAATTATGACGCATATGATTATTTTTTCAATAAAATAT
TTAAAAGATTTTTCACTTGAAAATGTTTATCCTTCGTGGACTGTACTTTTTATTGGTATT
GCTATCGCAGGATTGACGGCACCCGTTAGCGGATATTTTTTCATAGGTCAATTAACAGTA
ATATATGGCTTTGTAGCTACTTGTATTGTCTTACCTATAGTTTTCAAGCGATTAAAAGCA
TTTCCATTGCAGACGTCAATCAAACCGAACACATCGACAATTTGTGCACCATTTTCTTTA
GTCGCTGCAGCATATGTTATAGCTTTTCCTAAGGCGAATGCTTTTATCGTAATTATATTT
TTACTATTAGCTCAAATATTTTATTTTTATATCATTATACAATTGCCTAAATTACTAAAA
GAACCTTTTTCGCCCGTATTTTCAGCTTTCACATTCCCTTTAGTAATCTCAGCAACTGCT
TTAAAGAACAGTTTGCCTGTACTTATGTTTCCAGACATTTGGAAAGGTCTTTTGTTTATC
GAAGTGTTATTAGCCACTGTAATAGTACTTAGAGTCTTTATAGGATATCTTCACTTCTTT
TTAAAAAAGGAAAAACAAGATAAATTTCTTCGTAATGCGTCTCAGTAA60
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948
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NWMN_1082 [new locus tag: NWMN_RS06130 ]
- symbol: Eta
- description: exfoliative toxin A
- length: 315
- theoretical pI: 10.026
- theoretical MW: 35310.5
- GRAVY: 1.01492
⊟Function[edit | edit source]
- TIGRFAM: undecaprenyl-phosphate glucose phosphotransferase (TIGR03023; EC 2.7.8.-; HMM-score: 3.6)
- TheSEED :
- putative permease
- PFAM: no clan defined SLAC1; Voltage-dependent anion channel (PF03595; HMM-score: 51.6)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 10
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0.9991
- Cell wall & surface Score: 0
- Extracellular Score: 0.0009
- LocateP: Multi-transmembrane
- Prediction by SwissProt Classification: Membrane
- Pathway Prediction: Sec-(SPI)
- Intracellular possibility: 0
- Signal peptide possibility: -0.5
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.029806
- TAT(Tat/SPI): 0.000796
- LIPO(Sec/SPII): 0.047632
- predicted transmembrane helices (TMHMM): 10
⊟Accession numbers[edit | edit source]
⊟Additional information (user-provided)[edit | edit source]
⊟Protein sequence[edit | edit source]
- MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLENVYPSWTVLFIGIAIAGLTAPVSGYFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLLLAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFFLKKEKQDKFLRNASQ
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator:
⊟Additional information (user-provided)[edit | edit source]
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Additional information (user-provided)[edit | edit source]
⊟Other information (user-provided)[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ P W O'Toole, T J Foster
Nucleotide sequence of the epidermolytic toxin A gene of Staphylococcus aureus.
J Bacteriol: 1987, 169(9);3910-5
[PubMed:3040667] [WorldCat.org] [DOI] (P p)