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NCBI: 06-JUL-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1379 [new locus tag: NWMN_RS07765 ]
  • pan locus tag?: SAUPAN003930000
  • symbol: hepT
  • pan gene symbol?: hepT
  • synonym:
  • product: heptaprenyl diphosphate synthase component II

⊟Additional information (user-provided)[edit | edit source]

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_1379 [new locus tag: NWMN_RS07765 ]
  • symbol: hepT
  • product: heptaprenyl diphosphate synthase component II
  • replicon: chromosome
  • strand: -
  • coordinates: 1545756..1546724
  • length: 969
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    GTGATTAACGTGGCAAAGTTAAACATGAACAATGAAATTAAGAAAGTGGAACAACGACTT
    GAAAAGGCAATAAAAAGTAAAGATTCTGTATTAGAACAGGCATCATTACACTTATTGTCT
    TCTGGTGGTAAAAGAGTACGCCCAGCATTTGTTATTCTGAGTAGCCAATTTGGCAAAGAT
    GAACAAACGTCTGAACAAACGTATCAAGTTGCAGTCGCATTAGAGTTAATTCATATGGCA
    ACACTTGTTCATGATGACGTTATTGATAAAAGCGACAAGCGTCGAGGCAAGTTAACCATA
    TCAAAGAAATGGGATCAGACAACTGCTATTTTAACTGGGAATTTTTTATTGGCATTAGGA
    CTTGAACACTTAATGGCCGTTAAAGATAATCGTGTACATCAATTGATATCTGAATCTATC
    GTTGATGTTTGTAGAGGGGAACTTTTCCAATTTCAAGACCAATTTAACAGTCAACAGACA
    ATTATTAATTATTTACGACGTATCAATCGCAAAACAGCACTGTTAATTCAAATATCAACT
    GAAGTTGGTGCAATTACTTCTCAATCTGATAAAGAGACTGTACGAAAATTGAAAATGATT
    GGTCATTATATAGGTATGAGCTTCCAAATCATTGATGATGTATTAGACTTCACAAGTACC
    GAAAAGAAATTAGGTAAGCCGGTCGGAAGTGATTTGCTTAATGGTCATATTACGTTACCG
    ATTTTATTAGAAATGCGTAAAAATCCAGACTTCAAATTGAAAATCGAACAGTTACGTCGT
    GATAGTGAACGCAAAGAATTTGAAGAATGTATCCAAATCATTAGAAAATCTGACAGCATC
    GATGAGGCTAAGGCAGTAAGTTCGAAGTATTTAAGTAAAGCTTTGAATTTGATTTCTGAG
    TTACCAGATGGACATCCGAAATCACTACTTTTAAGTTTGACGAAAAAAATGGGTTCAAGA
    AACACGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    969


⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: NWMN_1379 [new locus tag: NWMN_RS07765 ]
  • symbol: HepT
  • description: heptaprenyl diphosphate synthase component II
  • length: 322
  • theoretical pI: 9.89584
  • theoretical MW: 36469
  • GRAVY: -0.331988

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone heptaprenyl diphosphate synthase component II (TIGR02748; EC 2.5.1.30; HMM-score: 378.9)
    and 1 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone solanesyl diphosphate synthase (TIGR02749; EC 2.5.1.-; HMM-score: 242.6)
  • TheSEED  :
    • Heptaprenyl diphosphate synthase component II (EC 2.5.1.30)
    Fatty Acids, Lipids, and Isoprenoids Isoprenoids Isoprenoid scratch  Heptaprenyl diphosphate synthase component II (EC 2.5.1.30)
    and 3 more
    Fatty Acids, Lipids, and Isoprenoids Isoprenoids Isoprenoinds for Quinones  Heptaprenyl diphosphate synthase component II (EC 2.5.1.30)
    Fatty Acids, Lipids, and Isoprenoids Isoprenoids Polyprenyl Diphosphate Biosynthesis  Heptaprenyl diphosphate synthase component II (EC 2.5.1.30)
    Regulation and Cell signaling Regulation and Cell signaling - no subcategory Sex pheromones in Enterococcus faecalis and other Firmicutes  Heptaprenyl diphosphate synthase component II (EC 2.5.1.30)
  • PFAM:
    Terp_synthase (CL0613) polyprenyl_synt; Polyprenyl synthetase (PF00348; HMM-score: 238.2)
    and 4 more
    HEPPP_synt_1; Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 (PF07307; HMM-score: 28.5)
    bHLH (CL0827) bHLH_INO2; INO2 bHLH domain (PF23179; HMM-score: 17.7)
    no clan defined Baculo_p33; Baculovirus P33 (PF05214; HMM-score: 16.5)
    NADP_Rossmann (CL0063) Pyr_redox_3; Pyridine nucleotide-disulphide oxidoreductase (PF13738; HMM-score: 14.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8848
    • Cytoplasmic Membrane Score: 0.105
    • Cell wall & surface Score: 0.0012
    • Extracellular Score: 0.009
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00786
    • TAT(Tat/SPI): 0.001301
    • LIPO(Sec/SPII): 0.000528
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MINVAKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILSSQFGKDEQTSEQTYQVAVALELIHMATLVHDDVIDKSDKRRGKLTISKKWDQTTAILTGNFLLALGLEHLMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIINYLRRINRKTALLIQISTEVGAITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILLEMRKNPDFKLKIEQLRRDSERKEFEECIQIIRKSDSIDEAKAVSSKYLSKALNLISELPDGHPKSLLLSLTKKMGSRNT

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Additional information (user-provided)[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Other information (user-provided)[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]


⊟Relevant publications[edit | edit source]

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